SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Pettersson Linda) srt2:(1999)"

Sökning: WFRF:(Pettersson Linda) > (1999)

  • Resultat 1-2 av 2
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Sigurd, Bengt, et al. (författare)
  • Svensk språkforskning under 1900-talet
  • 1999
  • Ingår i: Svenskans beskrivning 24 : Förhandlingar vid Tjugofjärde sammankomsten för svenskans beskrivning - Förhandlingar vid Tjugofjärde sammankomsten för svenskans beskrivning. - 9173733164 ; , s. 227-240
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • The development of Swedish linguistics during the 20th century reflects international development. The century started with focus on language history described according to the theory of sound laws. It is reasonable to call the period around the turn of the century the Golden Age of Nordic philology; characterized by the work of Adolf Noreen; Axel Kock and Elof Hellquist who clarified the basic development of Swedish and solved the etymologies of most Swedish words. Lexicography; onomastics and dialectology became Swedish specialties and were institutionalized. Around 1950 structuralism was introduced in Sweden; mainly by Bertil Malmberg who gained a chair in phonetics at Lund. Phonetics developed into a Swedish specialty by integrating technical aspects thanks to the work of Gunnar Fant. Noam Chomsky and generative grammar had a great influence in Sweden and Swedish syntax became an interesting field for young linguists who began publishing in English. Language learning research and psycholinguistics were also stimulated by generative grammar. Communication became a key concept for studies of interaction; dialogue and pragmatics. Computational linguistics made it possible to establish frequency dictionaries and large data bases for corpus linguistics. By the turn of the century 2000 the status of Swedish has been in question as the language seems to be threatened both by the involvement in EU and by the immigrant languages in Sweden. In a pessimistic perspective Swedish linguists will have to study the decline and fall of Swedish; in a more optimistic to study the survival of Swedish in a globalized world.
  •  
2.
  • Zeidman, Ruth, et al. (författare)
  • Novel and classical protein kinase C isoforms have different functions in proliferation, survival and differentiation of neuroblastoma cells
  • 1999
  • Ingår i: International Journal of Cancer. - 0020-7136. ; 81:3, s. 494-501
  • Tidskriftsartikel (refereegranskat)abstract
    • To elucidate the possibility of utilizing protein kinase C (PKC) isoforms as target genes in neuroblastoma therapy, 5 neuroblastoma cell lines and neuroblastoma tumor specimens were examined for PKC isoform expression pattern and the cell lines were analyzed for sensitivity to PKC inhibition. All cell lines [IMR-32, LAN-2, LAN-5, SH-SY5Y and SK-N-BE(2)] expressed alpha, betaII, delta and epsilon isoforms of PKC, while no PKCeta or theta protein was detected in any cell line. PKCgamma was found only in LAN-2 cells. PKCalpha, betaII and delta were detected in 5 neuroblastoma tumors and PKCepsilon in 4 out of 5 tumors. Exposure to the PKC inhibitors GF109203X, Go 6976 or Go 6983 caused a decrease whereas activation of PKC with 12-O-tetradecanoyl phorbol 13-acetate caused an increase in the number of neuroblastoma cells. The effect of Go 6976 was due to both inhibited proliferation and to increased apoptosis. While GF109203X suppressed neurite outgrowth induced by a growth factor combination, Go 6976 potentiated neurite outgrowth. Our data suggest a role for classical PKC isoforms in neuroblastoma growth and survival and for novel isoforms in neurite outgrowth.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-2 av 2

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy