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| 3. |
- Shaw, Philip, et al.
(författare)
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Genre across cultures
- 2004
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Ingår i: World Englishes. - 0883-2919 .- 1467-971X. ; 23:3, s. 385-401
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Biegert, Jens, et al.
(författare)
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Control of the frequency chirp rate of high harmonic pulses
- 2004
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Ingår i: Springer Series in Chemical Physics. - 0172-6218. ; 79, s. 204-206
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Tidskriftsartikel (refereegranskat)abstract
- We measured the frequency chirp rate of harmonics 13 to 23 in argon by cross-correlation with a short femtosecond probe pulse. We directly measured the negative chirp due to the atomic dipole phase and demonstrated that an additional chirp on the pump pulse was transferred to the qth harmonic as q times the fundamental chirp.
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| 5. |
- Buckland, Philip I., et al.
(författare)
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A Database for Egyptian Entomology
- 2004
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Ingår i: Bulletin of the Entomological Society of Egypt. - 1110-0885. ; 81
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Tidskriftsartikel (refereegranskat)abstract
- EGBUGS, the Egyptian incarnation of the BUGS Coleopteran Ecology Package is a simple yet highly valuable aid to research and education in the fields of entomology and palaeoentomology. The ability to rapidly look up species habitat and distribution data compiled from various sources in itself saves hours of library and internet searching. Added to this is the ability to query habitat data and produce ecologically defined subsets of the EGBUGS dataset, and rapidly summarise the ecology of species found at a particular site, which again are tasks that would take hours to perform manually. It is hoped that the system will greatly benefit those working in the aforementioned fields, and even inspire others to engage in similar activities. The program can be freely downloaded from the BUGS2000 WWW site at http://www.bugs2000.org, and the authors would be grateful for comments, revisions and new data for entry.
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| 6. |
- Dopson, Mark, et al.
(författare)
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Characterization of Ferroplasma isolates and Ferroplasma acidarmanus sp. nov., extreme acidophiles from acid mine drainage and industrial bioleaching environments.
- 2004
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Ingår i: Appl Environ Microbiol. - 0099-2240 .- 1098-5336. ; 70:4, s. 2079-88
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Tidskriftsartikel (refereegranskat)abstract
- Three recently isolated extremely acidophilic archaeal strains have been shown to be phylogenetically similar to Ferroplasma acidiphilum Y(T) by 16S rRNA gene sequencing. All four Ferroplasma isolates were capable of growing chemoorganotrophically on yeast extract or a range of sugars and chemomixotrophically on ferrous iron and yeast extract or sugars, and isolate "Ferroplasma acidarmanus" Fer1(T) required much higher levels of organic carbon. All four isolates were facultative anaerobes, coupling chemoorganotrophic growth on yeast extract to the reduction of ferric iron. The temperature optima for the four isolates were between 35 and 42 degrees C and the pH optima were 1.0 to 1.7, and "F. acidarmanus" Fer1(T) was capable of growing at pH 0. The optimum yeast extract concentration for "F. acidarmanus" Fer1(T) was higher than that for the other three isolates. Phenotypic results suggested that isolate "F. acidarmanus" Fer1(T) is of a different species than the other three strains, and 16S rRNA sequence data, DNA-DNA similarity values, and two-dimensional polyacrylamide gel electrophoresis protein profiles clearly showed that strains DR1, MT17, and Y(T) group as a single species. "F. acidarmanus" Fer1(T) groups separately, and we propose the new species "F. acidarmanus" Fer1(T) sp. nov.
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| 7. |
- Dopson, Mark, et al.
(författare)
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Growth in sulfidic mineral environments : metal resistance mechanisms in acidophilic micro-organisms.
- 2003
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Ingår i: Microbiology. - : Microbiology Society. - 1350-0872 .- 1465-2080. ; 149:8, s. 1959-1970
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Tidskriftsartikel (refereegranskat)abstract
- Acidophilic micro-organisms inhabit some of the most metal-rich environments known, including both natural and man-made ecosystems, and as such are ideal model systems for study of microbial metal resistance. Although metal resistance systems have been studied in neutrophilic micro-organisms, it is only in recent years that attention has been placed on metal resistance in acidophiles. The five metal resistance mechanisms identified in neutrophiles are also present in acidophiles, in some cases utilizing homologous proteins, but in many cases the degree of resistance is greater in acidophiles. This review summarizes the knowledge of acidophile metal resistance and presents preliminary in silico studies on a few known metal resistance systems in the sequenced acidophile genomes.
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| 9. |
- Liu, Jian, et al.
(författare)
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Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria
- 2004
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Ingår i: Neuron. - : Cell Press. - 0896-6273 .- 1097-4199. ; 43:1, s. 5-17
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Tidskriftsartikel (refereegranskat)abstract
- One cause of amyotrophic lateral sclerosis (ALS) is mutation in ubiquitously expressed copper/zinc superoxide dismutase (SOD1), but the mechanism of toxicity to motor neurons is unknown. Multiple disease-causing mutants, but not wild-type SOD1, are now demonstrated to be recruited to mitochondria, but only in affected tissues. This is independent of the copper chaperone for SOD1 and dismutase activity. Highly preferential association with spinal cord mitochondria is seen in human ALS for a mutant SOD1 that accumulates only to trace cytoplasmic levels. Despite variable proportions that are successfully imported, nearly constant amounts of SOD1 mutants and covalently damaged adducts of them accumulate as apparent import intermediates and/or are tightly aggregated or crosslinked onto integral membrane components on the cytoplasmic face of those mitochondria. These findings implicate damage from action of spinal cord-specific factors that recruit mutant SOD1 to spinal mitochondria as the basis for their selective toxicity in ALS.
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