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Tidskriftsartikel (refereegranskat)
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- Basu, P, et al.
(författare)
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Erratum
- 2018
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Ingår i: International journal of cancer. - : Wiley. - 1097-0215 .- 0020-7136. ; 143:1, s. E1-E1
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Tidskriftsartikel (refereegranskat)
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- Cannone, N., et al.
(författare)
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Effects of active layer seasonal dynamics and plant phenology on CO2 land-atmosphere fluxes at polygonal tundra in the High Arctic, Svalbard
- 2019
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Ingår i: Catena. - : Elsevier BV. - 0341-8162. ; 174, s. 142-153
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Tidskriftsartikel (refereegranskat)abstract
- Terrestrial Arctic ecosystems play a key role in the global carbon (C) cycle, as they store a large amount of organic matter in permafrost. Among regions with continuous permafrost, Svalbard has one of the warmest permafrost and may provide a template of the environmental responses of Arctic regions to future climate change. We analyze the CO2 fluxes at a polygonal tundra site in Adventdalen (Svalbard) during one full growing season across a vegetation and environmental gradient to understand how the interaction of different abiotic (thaw depth, ground surface temperature (GST), soil moisture, photosynthetic active radiation - PAR) and biotic (leaf area index (LAI), and plant phenology) factors affect the CO2 fluxes and identify the drivers of Net Ecosystem Exchange (NEE) and Ecosystem Respiration (ER). Three distinct periods (early, peak, and late) characterized the growing season based on plant phenology and the main environmental conditions. Comparing early, peak and late season, both NEE and ER exhibited specific patterns: ER shown high values since the early season, only slightly increased at peak, and then decreased drastically in the late season, with GST being the most important driver of ER. The drivers of NEE changed during the season: thaw depth, PAR and GST during the early season, LAI at peak, and PAR during the late season. These data allow to highlight that the thawing and freezing of the upper part of the active layer during the early and late season controls ER, possibly due to the response of microbial respiration in the upper part of the soil. Especially during the late season, despite the fully developed active layer (reaching its highest thawing depth), the freezing of the uppermost 2 cm of soil induced the drastic decrease of the respiratory efflux. In addition, the seasonal C balance of our plots indicated a seasonal source at our plots, in apparent contrast with previous eddy covariance (EC) measurements from a wetter area nearby. This difference implies that drier ecosystems act as sources while wetter ecosystems are sinks, suggesting that a drying trend in polygonal tundra could switch these ecosystems from CO2 sinks to sources in a feedback to future climate change.
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- Senore, C, et al.
(författare)
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Performance of colorectal cancer screening in the European Union Member States: data from the second European screening report
- 2019
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Ingår i: Gut. - : BMJ. - 1468-3288 .- 0017-5749. ; 68:7, s. 1232-1244
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Tidskriftsartikel (refereegranskat)abstract
- To present comparative data about the performance of colorectal cancer (CRC) screening programmes in the European Union Member States (EU MSs).DesignCross-sectional study. We analysed key performance indicators—participation rate, positivity rate (PR), detection rate (DR) and positive predictive value for adenomas and CRC—based on the aggregated quantitative data collected for the second EU screening report. We derived crude and pooled (through a random effects model) estimates to describe and compare trends across different MSs/regions and screening protocols.ResultsParticipation rate was higher in countries adopting faecal immunochemical test (FIT) (range: 22.8%–71.3%) than in those using guaiac faecal occult blood test (gFOBT) (range 4.5%–66.6%), and it showed a positive correlation (ρ=0.842, p<0.001) with participation in breast cancer screening in the same areas. Screening performance showed a large variability. Compliance with referral for colonoscopy (total colonoscopy (TC)) assessment ranged between 64% and 92%; TC completion rate ranged between 92% and 99%. PR and DR of advanced adenomas and CRC were higher in FIT, as compared with gFOBT programmes, and independent of the protocol among men, older subjects and those performing their first screening.ConclusionsThe variability in the results of quality indicators across population-based screening programmes highlights the importance of continuous monitoring, as well as the need to promote quality improvement efforts, as recommended in the EU guidelines. The implementation of monitoring systems, ensuring availability of data for the entire process, together with initiatives aimed to enhance reproducibility of histology and quality of endoscopy, represent a priority in screening programmes management.
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