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Träfflista för sökning "WFRF:(Poulsen G) srt2:(2020-2024)"

Sökning: WFRF:(Poulsen G) > (2020-2024)

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  • Bousquet, J, et al. (författare)
  • Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies
  • 2020
  • Ingår i: Clinical and translational allergy. - : Wiley. - 2045-7022. ; 10:1, s. 58-
  • Tidskriftsartikel (refereegranskat)abstract
    • There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPARγ:Peroxisome proliferator-activated receptor, NFκB: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2α:Elongation initiation factor 2α). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT1R axis (AT1R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity.
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  • Aad, G., et al. (författare)
  • Measurement of the jet mass in high transverse momentum Z(→bb‾)γ production at s=13TeV using the ATLAS detector
  • 2021
  • Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 812
  • Tidskriftsartikel (refereegranskat)abstract
    • The integrated fiducial cross-section and unfolded differential jet mass spectrum of high transverse momentum Z→bb‾ decays are measured in Zγ events in proton–proton collisions at s=13TeV. The data analysed were collected between 2015 and 2016 with the ATLAS detector at the Large Hadron Collider and correspond to an integrated luminosity of 36.1fb−1. Photons are required to have a transverse momentum pT>175GeV. The Z→bb‾ decay is reconstructed using a jet with pT>200GeV, found with the anti-kt R=1.0 jet algorithm, and groomed to remove soft and wide-angle radiation and to mitigate contributions from the underlying event and additional proton–proton collisions. Two different but related measurements are performed using two jet grooming definitions for reconstructing the Z→bb‾ decay: trimming and soft drop. These algorithms differ in their experimental and phenomenological implications regarding jet mass reconstruction and theoretical precision. To identify Z bosons, b-tagged R=0.2 track-jets matched to the groomed large-R calorimeter jet are used as a proxy for the b-quarks. The signal yield is determined from fits of the data-driven background templates to the different jet mass distributions for the two grooming methods. Integrated fiducial cross-sections and unfolded jet mass spectra for each grooming method are compared with leading-order theoretical predictions. The results are found to be in good agreement with Standard Model expectations within the current statistical and systematic uncertainties. © 2020 The Author
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  • Dramburg, S, et al. (författare)
  • EAACI Molecular Allergology User's Guide 2.0
  • 2023
  • Ingår i: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. - 1399-3038. ; 3434 Suppl 28, s. e13854-
  • Tidskriftsartikel (refereegranskat)
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