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- Nguyen, Thanh N, et al.
(författare)
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Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.
- 2023
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Ingår i: Neurology. - 1526-632X. ; 100:4
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Tidskriftsartikel (refereegranskat)abstract
- Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020).We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases.There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1-4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4-5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6-0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31-1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82-2.97], 5,656/195,539) of all stroke hospitalizations.There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.This study is registered under NCT04934020.
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- Gillespie, S. A., et al.
(författare)
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Identification of sub- μ s isomeric states in the odd-odd nucleus Au 178
- 2021
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Ingår i: Physical Review C. - 2469-9985. ; 103:4
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Tidskriftsartikel (refereegranskat)abstract
- The neutron-deficient gold (Z=79) isotopes in the vicinity of the neutron midshell N=104 provide prolific examples of shape coexistence and isomerism at low excitation energy. They can be probed via a number of different experimental techniques. In this study, two new isomeric states with half-lives of 294(7) and 373(9) ns have been observed in the neutron-deficient odd-odd nuclide Au178 (N=99) in an experiment at the RITU gas-filled separator at JYFL, Jyväskylä. This result was achieved due to the use of a segmented planar germanium detector with a high efficiency at low energies. By applying the recoil-decay tagging technique, they were assigned to decay to two different long-lived α-decaying states in Au178.
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- Prajapati, Rajaram, et al.
(författare)
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Streams, sewage, and shallow groundwater : stream-aquifer interactions in the Kathmandu Valley, Nepal
- 2021
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Ingår i: Sustainable Water Resources Management. - : Springer Science and Business Media LLC. - 2363-5037 .- 2363-5045. ; 7:5
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Tidskriftsartikel (refereegranskat)abstract
- The Kathmandu Valley in Nepal is facing a water quantity and quality crisis due to rapid urbanization and haphazard water and wastewater planning and management. Annually, groundwater extractions in the Kathmandu Valley exceed capture, resulting in groundwater table declines. Streams are often important sources of recharge to (or destination of discharges from) aquifers. However, stream-aquifer interactions in the Kathmandu Valley are poorly understood. To improve this understanding, we performed topographic surveys of water levels, and measured water quality, in streams and adjacent hand-dug wells (shallow aquifer). In pre-monsoon, 12% (2018) and 44% (2019) of wells had water levels higher than adjacent streams, indicating mostly a loss of stream water to the aquifer. However, in post-monsoon, 69% (2018) and 70% (2019) of wells had water levels higher than adjacent streams, indicating that monsoon rainfall contributes to shallow aquifer recharge which, at least temporarily, causes streams to transition from losing to gaining. Concentrations of all water quality parameters (electrical conductivity, ammonia, alkalinity, and hardness) were higher in the pre-monsoon compared to post-monsoon in both streams and wells. There was no recurring trend in water level difference longitudinally from upstream to downstream. However, water quality in streams and wells depleted from upstream to downstream. While we clearly observed seasonal refilling of the shallow aquifer, the role of the deep aquifer in seasonal storage processes deserve future research attention.
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- Saha, Anindya, et al.
(författare)
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Search for particle acceleration in two massive Wolf-Rayet stars using uGMRT observations
- 2023
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Ingår i: Monthly Notices of the Royal Astronomical Society. - 0035-8711 .- 1365-2966. ; 526:1, s. 750-757
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Tidskriftsartikel (refereegranskat)abstract
- Large wind kinetic power of Wolf-Rayet (WR) stars make them ideal targets in low radio frequencies to search for non-thermal emission due to relativistic particle acceleration. In this paper, we present observations of two WR stars, WR 114 and WR 142, in Band 4 (550-950 MHz) and Band 5 (1050-1450 MHz) using the upgraded Giant Meterwave Radio Telescope. Neither star is detected in the observed frequency bands, nor extended emission associated with them. The upper limit to the free-free radio emission from the stellar wind enables us to constrain the mass-loss rate of WR 114 to; this is a factor three smaller than previously estimated using spectroscopic modelling. If we further assume that the WR stars are binaries, the non-detection of synchrotron emission from the putative wind collision region implies that the stars are either in very wide binary systems away from periastron, or that the stars are in close binary systems with an orbital separation <70 AU for WR 114 and <20 AU for WR 142. The non-detection of low-frequency radio emission from these two systems thus provides evidence that narrows their nature, though it does not rule them out as bona fide particle-accelerating colliding-wind binaries.
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