| 1. |
- Bhattacharya, S., et al.
(författare)
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Evolution of collectivity and evidence of octupole correlations in Br 73
- 2019
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Ingår i: Physical Review C. - 2469-9985. ; 100:1
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Tidskriftsartikel (refereegranskat)abstract
- High-spin states in the Br73 nucleus have been populated via the Cr50(Si28,αp)Br73 fusion evaporation reaction with a beam energy of 90 MeV. The deexciting gamma rays were detected using the Indian National Gamma Array (INGA). Using the γ-γ coincidence technique, two new bands and eight new interconnecting transitions have been added. The strong interconnecting E1 transitions, between positive and negative parity bands, ensure the existence of octupole correlations at low spin. Line shapes have been observed for 17 transitions, which were analyzed by the Doppler-shift attenuation method to determine the lifetime of excited states of the yrast negative parity band and its signature partner band along with the positive parity band. The deduced transitional quadrupole moments Qt for the ground state band decrease with increasing spin, with their values ranging from 2.88 to 1.00 eb. A similar trend in the quadrupole moment has also been observed for the signature partner as well as for the positive parity band. This decrease in Qt with increasing spin for these bands is interpreted in terms of the cranked Nilsson-Strutinsky model and total Routhian surface calculations, which indicate possible band termination at higher spin.
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| 2. |
- Valassi, E., et al.
(författare)
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High mortality within 90 days of diagnosis in patients with Cushing's syndrome: results from the ERCUSYN registry
- 2019
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Ingår i: European Journal of Endocrinology. - : Oxford University Press (OUP). - 0804-4643 .- 1479-683X. ; 181:5, s. 461-472
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Patients with Cushing's syndrome (CS) have increased mortality. The aim of this study was to evaluate the causes and time of death in a large cohort of patients with CS and to establish factors associated with increased mortality. Methods: In this cohort study, we analyzed 1564 patients included in the European Registry on CS (ERCUSYN); 1045 (67%) had pituitary-dependent CS, 385 (25%) adrenal-dependent CS, 89 (5%) had an ectopic source and 45 (3%) other causes. The median (IQR) overall follow-up time in ERCUSYN was 2.7 (1.2-5.5) years. Results: Forty-nine patients had died at the time of the analysis; 23 (47%) with pituitary-dependent CS, 6 (12%) with adrenal-dependent CS, 18 (37%) with ectopic CS and two (4%) with CS due to other causes. Of 42 patients whose cause of death was known, 15 (36%) died due to progression of the underlying disease, 13 (31%) due to infections, 7 (17%) due to cardiovascular or cerebrovascular disease and 2 due to pulmonary embolism. The commonest cause of death in patients with pituitary-dependent CS and adrenal-dependent CS were infectious diseases (n = 8) and progression of the underlying tumor (n = 10) in patients with ectopic CS. Patients who had died were older and more often males, and had more frequently muscle weakness, diabetes mellitus and ectopic CS, compared to survivors. Of 49 deceased patients, 22 (45%) died within 90 days from start of treatment and 5 (10%) before any treatment was given. The commonest cause of deaths in these 27 patients were infections (n = 10; 37%). In a regression analysis, age, ectopic CS and active disease were independently associated with overall death before and within 90 days from the start of treatment. Conclusion: Mortality rate was highest in patients with ectopic CS. Infectious diseases the commonest cause of death soon after diagnosis, emphasizing the need for careful vigilance at that time, especially in patients presenting with concomitant diabetes mellitus.
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| 3. |
- Hartley, D. J., et al.
(författare)
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Persistence of collective behavior at high spin in the N=88 nucleus Tb-153
- 2015
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Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 91:5
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in the N = 88 nucleus Tb-153 were observed up to spin similar to 40 in an experiment utilizing the Gammasphere array. The Tb-153 states were populated in a weak alpha 4n evaporation channel of the Cl-37 + Sn-124 reaction. Two previously known sequences were extended to higher spins, and a new decoupled structure was identified. The pi h(11/2) band was observed in the spin region where other N = 88 isotopes exhibit effects of prolate to oblate shape changes leading to band termination along the yrast line, whereas Tb-153 displays a persistent collective behavior. However, minor perturbations of the very highest state in both signatures of this h(11/2) band are observed, which perhaps signal the start of the transition towards band termination.
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| 4. |
- Paul, E. S., et al.
(författare)
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Recent Results at Ultrahigh Spin: Terminating States and Beyond in Mass 160 Rare-earth Nuclei
- 2015
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Ingår i: Acta Physica Polonica. Series B: Elementary Particle Physics, Nuclear Physics, Statistical Physics, Theory of Relativity, Field Theory. - 0587-4254. ; 46:3, s. 487-496
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Tidskriftsartikel (refereegranskat)abstract
- A classic region of band termination at high spin occurs in rare-earth nuclei with around ten valence nucleons above the Gd-146 closed core. Results are presented here for such non-collective oblate (gamma = 60 degrees) terminating states in odd-Z Ho-155, odd-odd Ho-156, and even-even Er-156, where they are compared with neighbouring nuclei. In addition to these particularly favoured states, the occurrence of collective triaxial strongly deformed (TSD) bands, bypassing the terminating states and extending to over 65 (h) over bar, is reviewed.
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| 5. |
- Rees, J. M., et al.
(författare)
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High-spin terminating states in the N=88 Ho-155 and Er-156 isotones
- 2015
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Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 91:5
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Tidskriftsartikel (refereegranskat)abstract
- The Sn-124(Cl-37, 6n gamma) fusion-evaporation reaction at a bombarding energy of 180 MeV has been used to significantly extend the excitation level scheme of Ho-155(67)88. The collective rotational behavior of this nucleus breaks down above spin I similar to 30 and a fully aligned noncollective (band terminating) state has been identified at I-pi = 79/2(-). Comparison with cranked Nilsson-Strutinsky calculations also provides evidence for core-excited noncollective states at I-pi = 87/2(-) and (89/2(+)) involving particle-hole excitations across the Z = 64 shell gap. A similar core-excited state in Er-156(68)88 at I-pi = (46(+)) is also presented.
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| 6. |
- Wadsworth, R., et al.
(författare)
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Terminating states in the positive-parity structures of As 67
- 2018
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Ingår i: Physical Review C. - 2469-9985. ; 98:2
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Tidskriftsartikel (refereegranskat)abstract
- The energy levels and γ-ray decay scheme of the positive-parity states in the Tz=12 nucleus As67 have been studied by using the Ca40(Ar36,2αp)As67 reaction at a beam energy of 145 MeV. Two new band structures have been identified which can be connected to the previously known levels. The results for these bands are compared with configuration-dependent cranked Nilsson-Strutinsky calculations. The good level of agreement between theory and experiment suggests that these structures can be interpreted in terms of configurations that involve three g92 particles and that both possess noncollective terminating states.
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| 7. |
- Albers, M., et al.
(författare)
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Single-particle and collective excitations in Ni 62
- 2016
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Ingår i: Physical Review C - Nuclear Physics. - 0556-2813. ; 94:3
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Tidskriftsartikel (refereegranskat)abstract
- Background: Level sequences of rotational character have been observed in several nuclei in the A=60 mass region. The importance of the deformation-driving πf7/2 and νg9/2 orbitals on the onset of nuclear deformation is stressed. Purpose: A measurement was performed in order to identify collective rotational structures in the relatively neutron-rich Ni62 isotope. Method: The Mg26(Ca48,2α4nγ)Ni62 complex reaction at beam energies between 275 and 320 MeV was utilized. Reaction products were identified in mass (A) and charge (Z) with the fragment mass analyzer (FMA) and γ rays were detected with the Gammasphere array. Results: Two collective bands, built upon states of single-particle character, were identified and sizable deformation was assigned to both sequences based on the measured transitional quadrupole moments, herewith quantifying the deformation at high spin. Conclusions: Based on cranked Nilsson-Strutinsky calculations and comparisons with deformed bands in the A=60 mass region, the two rotational bands are understood as being associated with configurations involving multiple f7/2 protons and g9/2 neutrons, driving the nucleus to sizable prolate deformation.
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| 8. |
- Bridel, Claire, et al.
(författare)
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Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology : A Systematic Review and Meta-analysis
- 2019
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Ingår i: JAMA Neurology. - : American Medical Association (AMA). - 2168-6149 .- 2168-6157. ; 76:9, s. 1035-1048
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Forskningsöversikt (refereegranskat)abstract
- Importance Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number of neurological conditions compared with healthy controls (HC) and is a candidate biomarker for neuroaxonal damage. The influence of age and sex is largely unknown, and levels across neurological disorders have not been compared systematically to date.Objectives To assess the associations of age, sex, and diagnosis with NfL in CSF (cNfL) and to evaluate its potential in discriminating clinically similar conditions.Data Sources PubMed was searched for studies published between January 1, 2006, and January 1, 2016, reporting cNfL levels (using the search terms neurofilament light and cerebrospinal fluid) in neurological or psychiatric conditions and/or in HC.Study Selection Studies reporting NfL levels measured in lumbar CSF using a commercially available immunoassay, as well as age and sex.Data Extraction and Synthesis Individual-level data were requested from study authors. Generalized linear mixed-effects models were used to estimate the fixed effects of age, sex, and diagnosis on log-transformed NfL levels, with cohort of origin modeled as a random intercept.Main Outcome and Measure The cNfL levels adjusted for age and sex across diagnoses.Results Data were collected for 10 059 individuals (mean [SD] age, 59.7 [18.8] years; 54.1% female). Thirty-five diagnoses were identified, including inflammatory diseases of the central nervous system (n = 2795), dementias and predementia stages (n = 4284), parkinsonian disorders (n = 984), and HC (n = 1332). The cNfL was elevated compared with HC in a majority of neurological conditions studied. Highest levels were observed in cognitively impaired HIV-positive individuals (iHIV), amyotrophic lateral sclerosis, frontotemporal dementia (FTD), and Huntington disease. In 33.3% of diagnoses, including HC, multiple sclerosis, Alzheimer disease (AD), and Parkinson disease (PD), cNfL was higher in men than women. The cNfL increased with age in HC and a majority of neurological conditions, although the association was strongest in HC. The cNfL overlapped in most clinically similar diagnoses except for FTD and iHIV, which segregated from other dementias, and PD, which segregated from atypical parkinsonian syndromes.Conclusions and Relevance These data support the use of cNfL as a biomarker of neuroaxonal damage and indicate that age-specific and sex-specific (and in some cases disease-specific) reference values may be needed. The cNfL has potential to assist the differentiation of FTD from AD and PD from atypical parkinsonian syndromes.
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| 9. |
- Petrache, C. M., et al.
(författare)
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Search for the terminating 27(-) state in Nd-140
- 2015
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 92:3
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Tidskriftsartikel (refereegranskat)abstract
- In the search for the fully aligned 27(-) state in Nd-140 predicted by cranked Nilsson-Strutinsky calculations, new close-to-spherical high-spin states have been discovered. Both the close-to-spherical and the triaxial calculated states are in good agreement with the experimental results, supporting the existence of shape coexistence up to very high spins. Shell-model calculations using a newly developed effective interaction for the 50 <= N, Z <= 82 mass region are in good agreement with the observed spherical states. The comparison between the experimental and calculated level energies allowed the relative energy to be established between several proton and neutron orbitals at high energy and spins.
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| 10. |
- Saha, S., et al.
(författare)
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Observation of rotation about the longest principal axis in Zr 89
- 2019
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Ingår i: Physical Review C. - 2469-9985. ; 99:5
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Tidskriftsartikel (refereegranskat)abstract
- High-spin states in Zr89 were populated in the Se80(C13,4n) reaction, and γ-ray coincidences were measured using the Indian National Gamma Array. The level scheme of Zr89 has been extended up to spin I=49/2 with the observation of a new dipole band. Directional correlation and polarization asymmetries of the γ rays have been measured to determine spin and parity of the levels. Line shapes of several transitions have been analyzed to determine lifetimes of the levels. Possible configurations of the band have been discussed using the cranked Nilsson-Strutinsky model. The calculations suggest a triaxial shape of the nucleus at high spins, and the band may represent rotation of the nucleus about the longest axis.
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