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- Rees, D C, et al.
(författare)
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Born to clot : the European burden.
- 1999
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Ingår i: British Journal of Haematology. - 0007-1048 .- 1365-2141. ; 105:2, s. 564-6
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Tidskriftsartikel (refereegranskat)abstract
- Venous thrombosis is a common problem, predominantly afflicting people of European origin. This European predisposition has been explained to some extent by the recent characterization of factor V Leiden, and the G20210A prothrombin variant. Although it is clear that factor V Leiden is largely confined to Europeans, the world distribution of the prothrombin variant is not known. We have analysed samples from 22 different non-European countries and shown that this prothrombin variant is very rare outside Europe: one case occurring in India. The reason for the confined distribution of these two mutations is unclear.
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