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| 2. |
- Abbafati, Cristiana, et al.
(författare)
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- 2020
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Tidskriftsartikel (refereegranskat)
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| 3. |
- Bidgoli, Ali M., et al.
(författare)
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NeuroPIM : Felxible Neural Accelerator for Processing-in-Memory Architectures
- 2023
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Ingår i: Proceedings - 2023 26th International Symposium on Design and Diagnostics of Electronic Circuits and Systems, DDECS 2023. - : Institute of Electrical and Electronics Engineers Inc.. - 9798350332773 ; , s. 51-56
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Konferensbidrag (refereegranskat)abstract
- The performance of microprocessors under many modern workloads is mainly limited by the off-chip memory bandwidth. The emerging process-in-memory paradigm present a unique opportunity to reduce data movement overheads by moving computation closer to memory. State-of-the-art processing-in-memory proposals stack a logic layer on top of one or multiple memory layers in a 3D fashion and leverage the logic layer to build near-memory processing units. Such processing units are either application-specific accelerators or general-purpose cores. In this paper, we present NeuroPIM, a new processing-in-memory architecture that uses a neural network as the memory-side general-purpose accelerator. This design is mainly motivated by the observation that in many real-world applications, some program regions, or even the entire program, can be replaced by a neural network that is learned to approximate the program's output. NeuroPIM benefits from both the flexibility of general-purpose processors and superior performance of application-specific accelerators. Experimental results show that NeuroPIM provides up to 41% speedup over a processor-side neural network accelerator and up to 8x speedup over a general-purpose processor.
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| 4. |
- Kinyoki, DK, et al.
(författare)
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Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
- 2020
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Ingår i: Nature medicine. - : Springer Science and Business Media LLC. - 1546-170X .- 1078-8956. ; 26:5, s. 750-759
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Tidskriftsartikel (refereegranskat)abstract
- A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic.
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| 5. |
- Naghdi, Shahab, et al.
(författare)
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A starch-based pH-sensing and ammonia detector film containing betacyanin of paperflower for application in intelligent packaging of fish
- 2021
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Ingår i: International Journal of Biological Macromolecules. - : Elsevier BV. - 0141-8130 .- 1879-0003. ; 191, s. 161-170
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Tidskriftsartikel (refereegranskat)abstract
- An easy-to-use food packaging label with pH and ammonia sensitivity was developed by adding betacyanin (5, 10 and 15 mg per g of starch) from flowers of paperflower (Bougainvillea glabra) to potato starch film made using the solvent casting method. The betacyanin was well dispersed into the starch matrix and formed new interactions with it as revealed by FTIR. The film containing 15 mg/g of betacyanin showed a color change from light pink to yellow as a response to pH adjustment of between 2 to 13. It was also able to detect the presence of ammonia in a range of 0.1 and 0.01 mg of ammonia per ml of water. Surface hydrophobicity and water vapor barrier capacity of the starch film increased by addition of the betacyanin, yet their mechanical strength decreased in the presence of the betacyanin. The ability of the film in the real-time indication of fish quality as a label was also evaluated during the storage of Caspian sprat at 4 °C. A visual change in the color of the packaging label from pink to yellow in parallel with the increase in the total volatile basic nitrogen (TVB-N), microbial count of the fish samples was detected. The starch/betacyanin film could be a novel intelligent label for application in food packaging.
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| 6. |
- Naghdi, Shahab, et al.
(författare)
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Extraction of sulfated polysaccharide from Skipjack tuna (Katsuwonus pelamis) viscera using alcalase enzyme and rainbow trout (Oncorhynchus mykiss) visceral semi-purified alkaline proteases
- 2023
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Ingår i: Sustainable Chemistry and Pharmacy. - : Elsevier BV. - 2352-5541. ; 32
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Tidskriftsartikel (refereegranskat)abstract
- Fisheries produce a considerable amount of by-products per ton of processed fish, which ranges from 350 to 600 kg. Currently, most of these by-products are used as fish and shrimp meal or as fertilizer, even though they contain significant amounts of quality proteins (enzymes), polysaccharides, and polyunsaturated fats. The present study deals with the extraction of crude alkaline proteases (AP) from rainbow trout (Oncorhynchus mykiss) viscera. The enzyme precipitated at 30–60% saturation displayed the highest yield, purity, and activity compared to other saturation ranges. The maximum activity of AP was obtained at 60 °C and pH 7. AP, ultrasound-AP, Alcalase, and ultrasound-Alcalase were used to isolate sulfated polysaccharides (SPs) from Skipjack tuna (Katsuwonus pelamis) viscera. The extraction yields showed no significant difference between all extracted SPs (p > 0.05). APU-Viscera-SP, AlU-Viscera-SP, and Al-Viscera-SP contained the most sugar (62.22%), sulfate (15.93%), uronic acid (8.84%), and protein (12.69%), respectively. Also, all SPs showed a mixed composition of monosaccharides, including xylose, mannose, rhamnose, GalA (galacturonic acid) and glucuronic acid (GlcA). AP-Viscera-SP, AlU-Viscera-SP, and AlU-Viscera-SP exhibited the highest antioxidant activity in DPPH, ABTS, and metal chelating tests. The highest inhibitor zone against L. monocytogenes, S. aureus, B. cereus, S. enterica, E. coli, and S. typhimurium were in APU-Viscera-SP, and AlU-Viscera-SP, respectively. Overall, the obtained results demonstrated that fish viscera could be a good source of alkaline protease. Besides, this obtained alkaline protease can also be used to extract sulfated polysaccharides with bioactive and functional properties from fish viscera byproducts.
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| 7. |
- Naghdi, Shahab, et al.
(författare)
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Fish Protein Hydrolysate from Sulfated Polysaccharides Extraction Residue of Tuna Processing By-Products with Bioactive and Functional Properties
- 2023
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Ingår i: Global Challenges. - : Wiley. - 2056-6646. ; 7:4
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Tidskriftsartikel (refereegranskat)abstract
- The ethanol-induced precipitation after enzymatic hydrolysis commonly used for sulfated polysaccharide extraction from marine resources wastes a large amount of proteins. Here, possible extraction of fish protein hydrolysates (FPH) from the ethanol residue of sulfated polysaccharide precipitation from head, bone, and skin of skipjack tuna is investigated. Antioxidant, antibacterial, angiotensin I-converting enzyme (ACE) inhibitory activities and functional properties of the recovered FPHs are also evaluated. A degree of hydrolysis of 40.93, 38.13, and 37.23 is achieved for FPH from head, bone, and skin, respectively. FPH from the head presents the highest antioxidant and ACE inhibitory activity as well as foam/emulsion capacity among all the FPHs. The FPHs are all able to inhibit three Gram-positive bacteria and three Gram-negative bacteria to varying degrees and have a water solubility >65%. Altogether, the results demonstrate great potential for recovery of bioactive/functional peptides from the residue of sulfated polysaccharide extraction process enabling efficient biorefining of aquatic resources.
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| 8. |
- Naghdi, Shahab, et al.
(författare)
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Parallel Extraction of Sulfated polysaccharides and Protein Hydrolysate from Skipjack Tuna Head and Their Bioactive and Functional Properties
- 2023
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Ingår i: Food and Bioprocess Technology. - : Springer Science and Business Media LLC. - 1935-5130 .- 1935-5149. ; 16:6, s. 1258-1279
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Tidskriftsartikel (refereegranskat)abstract
- A new process for parallel extraction of sulfated polysaccharides (SPs) and fish protein hydrolysate (FPH) from tuna head was developed. The effect of type of enzymes (Alcalase, Protamex, and Pancreatin) on the structural, functional, and bioactivity of both SPs and FPHs was also investigated. Initially, SPs were extracted, then the remaining ethanol from polysaccharide precipitation was used to obtain hydrolyzed proteins. Protamex produced SPs with the highest carbohydrate content (50.17%) while Alcalase prompted the highest content of uronic acid/sulfate. The degree of hydrolysis of the FPHs varied by the used enzyme but their amino acid composition fulfilled human requirements. Both SPs and FPHs had antioxidant activity but their efficiency was governed by the type of enzyme and oxidation mechanism. SPs had good metal chelation while FPHs showed good radical scavenging. Recovered FPHs had substantially higher antibacterial activity than the SPs and showed the highest inhibition against E. coli in concentration of 1 mg/mL. Altogether, parallel extraction of SPs and FPHs could be a promising biorefinery approach for more efficient utilization of tuna head.
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| 9. |
- Naghdi, Shahab, et al.
(författare)
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Ultrasonic-assisted enzymatic extraction of sulfated polysaccharide from Skipjack tuna by-products
- 2023
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Ingår i: Ultrasonics Sonochemistry. - : Elsevier BV. - 1873-2828 .- 1350-4177. ; 95
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Tidskriftsartikel (refereegranskat)abstract
- The effect of ultrasound pretreatment on extraction efficiency of sulfate polysaccharides (SPs) using alcalase from different by-products of Skipjack tuna including head, bone and skin was evaluated. Structural, functional, antioxidant and antibacterial properties of the recovered SPs using the ultrasound-enzyme and enzymatic method were also investigated. Ultrasound pretreatment significantly increased the extraction yield of SPs from all the three by-products compared with the conventional enzymatic method. All extracted SPs showed high antioxidant potential in terms of ABTS, DPPH and ferrous chelating activities where the ultrasound treatment enhanced antioxidant activities of the SPs. The SPs exerted strong inhibiting activity against various Gram-positive and Gram-negative bacteria. The ultrasound treatment remarkably increased antibacterial activity of the SPs against L. monocytogenes but its effect on other bacteria was dependent on the source of the SPs. Altogether, the results suggest that ultrasound pretreatment during enzymatic extraction of SPs from tuna by-products can be a promising approach to improve extraction yield but also bioactivity of the extracted polysaccharides.
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| 10. |
- Pezeshk, Samaneh, et al.
(författare)
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Impact of pH-shift processing combined with ultrasonication on structural and functional properties of proteins isolated from rainbow trout by-products
- 2021
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Ingår i: Food Hydrocolloids. - : Elsevier BV. - 0268-005X. ; 118
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Tidskriftsartikel (refereegranskat)abstract
- The effects of alkaline and acid solubilization pHs (11, 11.5, 3.5 and 2.5) combined with ultrasonication (100, and 400 W for 0, 5, 10 and 20 min) on protein recovery from rainbow trout by-product and its structural and functional properties were investigated. The combination of pH-shift processing with ultrasonication increased protein solubilization and total yield compared with the classic pH-shift processing. The combination also significantly reduced particle size, tryptophan fluorescence intensity, and reactive sulfhydryl groups content of the protein isolates. The secondary structure of the proteins was also influenced by ultrasonication with decreasing in α-helix and increasing in β-sheet, β-turn and random coil content. However, SDS-PAGE demonstrated no difference in the molar masses of the proteins. Emulsifying and foaming properties of the proteins improved by applying the combined method. However, the level of improvements was governed by solubilization pH as well as ultrasound exposure power and time. Altogether, pH-shift processing combined with ultrasonication increased protein recovery from the fish by-products while the structural changes induced with the combination improved functional properties of the recovered proteins.
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