| 2. |
- Pizarro, Ana Beatriz, et al.
(författare)
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Workplace interventions to reduce the risk of SARS-CoV-2 infection outside of healthcare settings
- 2022
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Ingår i: Cochrane Database of Systematic Reviews. - 1465-1858. ; 5:5, s. CD015112-
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Forskningsöversikt (refereegranskat)abstract
- Background: Although many people infected with SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) experience no or mild symptoms, some individuals can develop severe illness and may die, particularly older people and those with underlying medical problems. Providing evidence-based interventions to prevent SARS-CoV-2 infection has become more urgent with the spread of more infectious SARS-CoV-2 variants of concern (VoC), and the potential psychological toll imposed by the coronavirus disease 2019 (COVID-19) pandemic. Controlling exposures to occupational hazards is the fundamental method of protecting workers. When it comes to the transmission of viruses, such as SARS-CoV-2, workplaces should first consider control measures that can potentially have the most significant impact. According to the hierarchy of controls, one should first consider elimination (and substitution), then engineering controls, administrative controls, and lastly, personal protective equipment (PPE). Objectives: To assess the benefits and harms of interventions in non-healthcare-related workplaces to reduce the risk of SARS-CoV-2 infection relative to other interventions, or no intervention. Search methods: We searched MEDLINE, Embase, Web of Science, Cochrane COVID-19 Study Register, the Canadian Centre for Occupational Health and Safety (CCOHS), Clinicaltrials.gov, and the International Clinical Trials Registry Platform to 14 September 2021. We will conduct an update of this review in six months. Selection criteria: We included randomised control trials (RCT) and planned to include non-randomised studies of interventions. We included adult workers, both those who come into close contact with clients or customers (e.g. public-facing employees, such as cashiers or taxi drivers), and those who do not, but who could be infected by co-workers. We excluded studies involving healthcare workers. We included any intervention to prevent or reduce workers' exposure to SARS-CoV-2 in the workplace, defining categories of intervention according to the hierarchy of hazard controls, i.e. elimination; engineering controls; administrative controls; personal protective equipment. Data collection and analysis: We used standard Cochrane methods. Our primary outcomes were incidence rate of SARS-CoV-2 infection (or other respiratory viruses), SARS-CoV-2-related mortality, adverse events, and absenteeism from work. Our secondary outcomes were all-cause mortality, quality of life, hospitalisation, and uptake, acceptability, or adherence to strategies. We used the Cochrane RoB 2 tool to assess the risk of bias, and GRADE methods to assess the certainty of evidence for each outcome. Main results: Elimination of exposure interventions. We included one study examining an intervention that focused on elimination of hazards. This study is an open-label, cluster-randomised, non-inferiority trial, conducted in England in 2021. The study compared standard 10-day self-isolation after contact with an infected person to a new strategy of daily rapid antigen testing and staying at work if the test is negative (test-based attendance). The trialists hypothesised that this would lead to a similar rate of infections, but lower COVID-related absence. Staff (N = 11,798) working at 76 schools were assigned to standard isolation, and staff (N = 12,229) at 86 schools to the test-based attendance strategy. The results between test-based attendance and standard 10-day self-isolation were inconclusive for the rate of symptomatic PCR-positive SARS-COV-2 infection rate ratio ((RR) 1.28, 95% confidence interval (CI) 0.74 to 2.21; 1 study, very low-certainty evidence)). The results between test-based attendance and standard 10-day self-isolation were inconclusive for the rate of any PCR-positive SARS-COV-2 infection (RR 1.35, 95% CI 0.82 to 2.21; 1 study, very low-certainty evidence). COVID-related absenteeism rates were 3704 absence days in 566,502 days-at-risk (6.5 per 1000 days at risk) in the control group and 2932 per 539,805 days-at-risk (5.4 per 1000 days at risk) in the intervention group (RR 0.83; 95% CI 0.55 to 1.25). The certainty of the evidence was downgraded to low, due to imprecision. Uptake of the intervention was 71 % in the intervention group, but not reported for the control intervention. The trial did not measure other outcomes, SARS-CoV-2-related mortality, adverse events, all-cause mortality, quality of life, and hospitalisation. We found one ongoing RCT about screening in schools, using elimination of hazard strategies. Personal protective equipment. We found one ongoing non-randomised study on the effects of closed face shields to prevent COVID-19 transmission. Other intervention categories. We did not find studies in the other intervention categories. Authors' conclusions: We are uncertain whether a test-based attendance policy affects rates of PCR-postive SARS-CoV-2 infection (any infection; symptomatic infection) compared to standard 10-day self-isolation amongst school and college staff. Test-based attendance policy may result in little to no difference in absence rates compared to standard 10-day self-isolation. As a large part of the population is exposed in the case of a pandemic, an apparently small relative effect that would not be worthwhile from the individual perspective may still affect many people, and thus, become an important absolute effect from the enterprise or societal perspective. The included study did not report on any other primary outcomes of our review, i.e. SARS-CoV-2-related mortality and adverse events. No completed studies were identified on any other interventions specified in this review, but two eligible studies are ongoing. More controlled studies are needed on testing and isolation strategies, and working from home, as these have important implications for work organisations.
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| 3. |
- Rhodes, Emma, 1990-
(författare)
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Evolution of a silicic magma reservoir in the upper crust : Reyðarártindur pluton, Southeast Iceland
- 2022
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Field observations of extinct and exposed magma reservoirs shed light on processes operating in the roots of presently active volcanoes. The Reyðarártindur pluton, Southeast Iceland is an example of a fossil shallow magma reservoir that fed eruptions. The different chapters in this thesis examine the accumulation of magma, and processes occurring during the development and evolution of the magma reservoir from different methodological perspectives. A final model for the evolution of the Reyðarártindur pluton is then presented.The majority of the pluton consists of one voluminous rock unit, the Main Granite, that formed by rapid magma emplacement. However, a local zone of geochemically distinct, but related further Granite Enclaves and Quartz Monzonite Enclaves attest to variations in the composition of the underlying source reservoir. Space for the ca. 2.5 km3 of magma in the pluton was made by piecemeal floor subsidence, which began with multiple dykes that then propagated laterally to form flat-roofed intrusions at different depths. During the first stages of magma emplacement, shattering, sintering and sanidinite-facies contact metamorphism affected a ca. 10 m thick zone of the basalt host rock at the magma reservoir roof. The resulting hornfels was stronger than the original altered basalt, and contained zero porosity and permeability. It thus formed a ‘cap-rock’ to the magma reservoir, limiting heat, volatile and fluid transfer until fractured and faulted at a later stage. The magma reservoir erupted at least once, causing local subsidence of the roof, which would have been observable at the Earth’s surface. Recharge of the magma reservoir by the same Quartz Monzonite and further Granite as exposed in the Reyðará River led to overpressure and eruption. We envisage that cooling and sealing of the piecemeal subsidence network preceded eruption, causing overpressure with magma recharge. The eruptive lifetime of the magma reservoir was limited to ca. 1000 years. This timeframe is much less than the duration of silicic magmatism in a typical Icelandic central volcano, or at other rhyolite-erupting volcanoes worldwide, which is in the order of hundreds of thousands to millions of years. Hence, the Reyðarártindur pluton likely represents a small, ephemeral part of a wider magmatic plumbing system that feeds a central volcano.The results from these studies can provide volcano-monitoring personnel with scenarios for magma emplacement, and processes leading to eruption, which they can then use as a framework for interpreting detectable signals of magma movement and volcanic unrest.
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| 4. |
- Rhodes, Emma, 1990-, et al.
(författare)
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Rapid formation and eruption of a silicic magma chamber
- 2022
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Shallow magmatic reservoirs have been identified at many volcanoes worldwide. However, questions still remain regarding their size, dynamics and longevity. The Reyðarártindur Pluton exposed in Southeast Iceland provides a superb example to investigate the above questions. Here, we use field mapping, sampling, geochemistry, 3D pluton shape modelling and a numerical thermal model to reconstruct the assembly and eruptive history of the shallow magma body.In 3D, the c. 2.5 km3 pluton has a castle-like shape characterised by flat roof segments that are vertically offset along steep faults. The exposed pluton is constructed largely of a single rock unit, the Main Granite (69.9 to 77.6 wt.% SiO2). Two additional units occur only as enclaves: the Granite Enclaves (67.4 to 70.2 wt.% SiO2), and the Quartz Monzonite Enclaves (61.8 to 67.3 wt.% SiO2). However, geochemistry clearly indicates that the units are related and hence were likely derived from the same source reservoir. In two locations, the pluton roof displays depressions associated with large dykes. Within these two dykes the rock is partially to wholly tuffisitic, and geochemical compositions range from quartz monzonite to granite. We interpret these dykes as eruption-feeding conduits from the pluton. Additionally, we speculate that the mingling of magmatic units with compositional ranges from quartz monzonite to granite within the conduits indicates that injection of new magma into the reservoir triggered eruption. Rapid pluton construction is indicated by ductile contacts between units in the pluton and a thermal model calculates the top 75 m would have rheologically locked up within 1000 years. Hence, we argue that the pluton was a short-lived part of the wider magmatic system that fed the associated volcano, and that timeframes from emplacement to eruption were limited to 1000 years.Rhodes, E. Barker, A. K. Burchardt, S. et al. (2021). Rapid assembly and eruption of a shallow silicic magma reservoir, Reyðarártindur Pluton, Southeast Iceland. G-Cubed. DOI: 10.1029/2021GC009999
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