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- Veszelei, M, et al.
(författare)
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Optical constants of sputter-deposited Ti-Ce oxide and Zr-Ce oxide films
- 1998
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Ingår i: APPLIED OPTICS. - : OPTICAL SOC AMER. - 0003-6935. ; 37:25, s. 5993-6001
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Tidskriftsartikel (refereegranskat)abstract
- Films of Ti oxide, Zr oxide, Ce oxide, Ti-Ce oxide, and Zr-Ce oxide were made by means of reactive de magnetron sputtering in a multitarget arrangement. The films were characterized by x-ray diffraction and electrochemical measurements, both technique
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| 9. |
- Sundberg, Christian, et al.
(författare)
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Tumor cell and connective tissue cell interactions in human colorectal adenocarcinoma : Transfer of platelet-derived growth factor-AB/BB to stromal cells
- 1997
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Ingår i: American Journal of Pathology. - 0002-9440 .- 1525-2191. ; 151:2, s. 479-492
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Tidskriftsartikel (refereegranskat)abstract
- Mechanisms underlying stimulation of platelet-derived growth factor (PDGF) beta-receptors expressed on connective tissue cells in human colorectal adenocarcinoma were investigated in this study. PDGF-AB/BB, but not PDGF receptors, was expressed by tumor cells in situ, as well as in tumor cell isolates of low passage from human colorectal adenocarcinoma. In an experimental co-culture system, conditioned medium from tumor cells only marginally activated PDGF beta-receptors expressed on fibroblasts. In contrast, co-culturing of the two cell types led to a marked PDGF beta-receptor activation. Functional PDGF-AB/BB was found to be associated with heparinase-I-sensitive components on the tumor cell surface. PDGF-AB/BB, isolated from heparinase-I-sensitive cell surface components, induced a marked activation of PDGF beta-receptors. Furthermore, co-culturing tumor cells together with fibroblasts led to a sustained activation of PDGF beta-receptors expressed on fibroblasts. Double immunofluorescence staining of tissue sections from human colorectal adenocarcinoma, combined with computer-aided image analysis, revealed that nonproliferating tumor cells were the predominant cellular source of PDGF-AB/BB in the tumor stroma. In addition, PDGF-AB/BB-expressing tumor cells were found juxtapositioned to microvascular cells expressing activated PDGF beta-receptors. Confocal microscopy revealed a cytoplasmic and cell-membrane-associated expression of PDGF-AB/BB in tumor cells situated in the stroma. In contrast, epithelial cells situated in normal or tumorous acinar structures revealed only a cell-membrane-associated PDGF-AB/BB expression. The is vitro and in situ results demonstrate that tumor cells not only facilitate but also have the ability to modulate connective tissue cell responsiveness to PDGF-AB/BB in a paracrine fashion, through direct cell-cell interactions in human colorectal adenocarcinoma.
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| 10. |
- von, Rottkay K, et al.
(författare)
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Influence of stoichiometry on electrochromic cerium-titanium oxide compounds
- 1998
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Ingår i: SOLID STATE IONICS. - : ELSEVIER SCIENCE BV. - 0167-2738. ; 115, s. 425-430
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- CeO2-TiO2 finds use as passive counter-electrode in electrochromic devices. Thin films were produced by de-sputtering in a wide range of compositions. Influence of total pressure and oxygen partial pressure on the optical constants of TiO2 was investigate
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