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- Rumpunen, Kimmo, et al.
(författare)
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Antioxidative protection of dietary rosehips and polyphenol active lactobacilli in mice subjected to intestinal oxidative stress by ischemia reperfusion
- 2009
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Ingår i: Microbial Ecology in Health and Disease. - : Informa UK Limited. - 0891-060X .- 1651-2235. ; 21, s. 193-202
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Tidskriftsartikel (refereegranskat)abstract
- Background and aim: Ischemia-reperfusion (I/R) in the intestines activates leukocytes and reactive oxygen species (ROS) and leads to lipid peroxidation and DNA damage. Rosehips have a high content of polyphenols and might prevent lipid peroxidation. SomeLactobacillusspecies are capable of degrading polyphenols to simpler and non-toxic constituents, sometimes with enhanced antioxidative capacity.Methods: A mixture of eight polyphenol activeLactobacillusstrains (LAB) were administered in feed together with rosehips ofRosa canina(RC) orRosa pimpinellifolia(RP) to mice to clarify the influence on I/R-induced injury of the intestinal tract. I/R injury was induced by holding the superior mesenteric artery clamped for 30 min followed by reperfusion for 240 min. Tissue and content from colon and cecum were analyzed.Results: Administration of LAB or RP significantly decreased malondialdehyde (MDA) levels in colonic tissue (p=0.007 andp=0.035, respectively). RC contained significantly higher concentrations of monomer and dimer aglycones, glycosides, and catechin than RP, while cyanidin-3-O-glycoside was significantly higher in RP. There was a tendency towards higher values of phenolics in the mice fed either of the two rose species in combination with bacterial mixture than the mice fed the rose species alone. Total antioxidative capacity and total phenolic content were higher in the groups fed rosehips in combination with LAB than rosehips alone, although these differences were not significant.Conclusion: LAB showed metabolic activity towards polyphenols in rosehips. There is an indication that LAB together with rosehips, especiallyR. pimpinellifolia, may prevent and suppress I/R injury in the intestines.Read More:http://informahealthcare.com/doi/abs/10.3109/08910600903429045
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- Rumpunen, Kimmo
(författare)
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Myter och vetande om kunskapens frukt
- 2009
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Ingår i: Livskvalitet öster om leden : tankar om att steka ål, äta socker och bygga hus men också om frukten, supen, bakterien, hälsan & döden. - 9789197782906 ; , s. 97-106
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Bokkapitel (populärvet., debatt m.m.)
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- Rumpunen, Kimmo, et al.
(författare)
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Odla rabarber
- 2009
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Ingår i: Fakta. Trädgård / fritid. - 1102-1969.
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Annan publikation (populärvet., debatt m.m.)
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- Åkerström, Andreas, et al.
(författare)
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Effects of Sampling Time and Nitrogen Fertilization on Anthocyanidin Levels in Vaccinium myrtillus Fruits
- 2009
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Ingår i: Journal of Agricultural and Food Chemistry. - : American Chemical Society (ACS). - 0021-8561 .- 1520-5118. ; 57, s. 3340-3345
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Tidskriftsartikel (refereegranskat)abstract
- Vaccinium myrtillus berries (bilberries) contain antioxidants, in particular anthocyanins, which are secondary metabolites that have proven health-promoting effects. Bilberries were collected at the Svartberget research forest in northern Sweden from plots with no, low, and high applications of NH(4)NO(3) on three replicated dates in each year from 2005-2007, and their anthocyanidin contents were analyzed by high performance liquid chromatography. Their mean total anthocyanidin contents Were 9.0, 6.2, and 22.7 mg/g DW in 2005, 2006, and 2007, respectively. The values were significantly higher in 2005 than in 2006 and significantly higher in 2007 than in both previous years, across all three sampling dates. In addition, anthocyanidin contents were significantly affected by sampling date in all years (P < 0.001); they were linearly correlated with the thermal sum in 2005 and 2007 but rose between the first and second sampling occasions and subsequently declined in 2006. No significant effect of nitrogen fertilization on total anthocyanidin levels was detected in any of the studied years. The results indicate that climatic factors and yearly fluctuations influence anthocyanidin biosynthesis and degradation more strongly than nitrogen availability. To our knowledge, this is the first time this effect of sampling time on anthocyanins in mature bilberries has been shown.
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