| 1. |
- Aad, G., et al.
(författare)
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- 2013
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Stoor, Krister, 1959-
(författare)
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Svenska kyrkan och jojken
- 2016. - 1
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Ingår i: De historiska relationerna mellan Svenska kyrkan och samerna. - Skellefteå : Artos & Norma bokförlag. - 9789175807959 ; , s. 711-734
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Bokkapitel (refereegranskat)abstract
- Jojken är ett muntligt uttryck bland samer som funnits sedan urminnes tider. Att jojka var ett sätt att berätta och beskriva djur, människor, händelser, supranormala relationer etc. Eftersom jojken också användes som verktyg för nåjder eller personer med liknande kunskaper för att nå andra medium, blev jojken stämplad av kyrkan under 1600-talet som ett djävulens verk. Under lång tid var detta uttryckssätt förbjudet och straffbart. Men jojken försvann inte. Den levde sitt liv i det inofficiella rummet, långt borta ifrån den styrande eliten som oftast fanns vid kusten. Syndastämpeln som kyrkan så skickligt implanterat blev så småningom samernas egen syn på jojk på många håll. Trots det, när man studerar äldre inspelningar från början av 1910-talet och anteckningar från slutet av 1800-talet, ser man att många präster, särskilt i norra Västerbotten och södra Norrbotten varit mer än aktiva att dokumentera jojk. De har även blivit tillägnade egna melodier, det förnämsta man som jojkutövare någonsin kan skänka någon. Till och med bland læstadianska predikanter har det förekommit att man accepterat jojkning. "Jojkning är inte syndigt, blott man inte jojkar syndigt, liksom det ej heller är syndigt att dricka tvenne supar när det är kallt." Studien granskar jojkens roll hos den samiska befolkningen i relation till kyrkans folk, med fokus på 1900-talets utveckling.
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| 3. |
- de las Fuentes, Lisa, et al.
(författare)
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Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
- 2021
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Ingår i: Molecular Psychiatry. - : Springer Nature. - 1359-4184 .- 1476-5578. ; 26:6, s. 2111-2125
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Tidskriftsartikel (refereegranskat)abstract
- Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses accounting for gene-educational attainment interactions using two variables, “Some College” (yes/no) and “Graduated College” (yes/no). Interactions were evaluated using both a 1 degree of freedom (DF) interaction term and a 2DF joint test of genetic and interaction effects. Analyses were performed for systolic BP, diastolic BP, mean arterial pressure, and pulse pressure. We pursued genome-wide interrogation in Stage 1 studies (N = 117 438) and follow-up on promising variants in Stage 2 studies (N = 293 787) in five ancestry groups. Through combined meta-analyses of Stages 1 and 2, we identified 84 known and 18 novel BP loci at genome-wide significance level (P < 5 × 10-8). Two novel loci were identified based on the 1DF test of interaction with educational attainment, while the remaining 16 loci were identified through the 2DF joint test of genetic and interaction effects. Ten novel loci were identified in individuals of African ancestry. Several novel loci show strong biological plausibility since they involve physiologic systems implicated in BP regulation. They include genes involved in the central nervous system-adrenal signaling axis (ZDHHC17, CADPS, PIK3C2G), vascular structure and function (GNB3, CDON), and renal function (HAS2 and HAS2-AS1, SLIT3). Collectively, these findings suggest a role of educational attainment or SES in further dissection of the genetic architecture of BP.
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| 4. |
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| 5. |
- Lundgren, Henrik, et al.
(författare)
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Coping with Communication Gray Zones in IEEE 802.11b based Ad hoc Networks
- 2002
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Ingår i: Proceedings of the 5th ACM international workshop on Wireless mobile multimedi. - 1581134746
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Konferensbidrag (refereegranskat)abstract
- Our experiments with IEEE 802.11b based wireless ad hoc networks show that neighbor sensing with broadcast messages introduces "communication gray zones": in such zones data messages cannot be exchanged although the HELLO messages indicate neighbor reach
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| 6. |
- Nelson, Kenneth
(författare)
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Lower unemployment benefits and old-age pensions is a major setback in social policy
- 2017
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Ingår i: Sociologisk forskning. - : Sveriges Sociologförbund. - 0038-0342 .- 2002-066X. ; 54:4, s. 287-291
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Tidskriftsartikel (refereegranskat)abstract
- The Swedish welfare state has been subject to a substantial re-organization in recent decades, not always recognized in the international literature. Almost every area of social policy have changed, often in the downward direction and with potential far-reaching consequences for the social sustainability of the Swedish welfare state. In this research note, I discuss significant changes to Swedish social policy and place the reorganization of the Swedish welfare state in an international perspective. Focus is on old-age pensions and unemployment benefits. Both areas are characterized by significant changes.
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| 7. |
- Pecori, Riccardo, et al.
(författare)
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ADAR1-mediated RNA editing promotes B cell lymphomagenesis
- 2023
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Ingår i: iScience. - : Cell Press. - 2589-0042. ; 26:6
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Tidskriftsartikel (refereegranskat)abstract
- Diffuse large B cell lymphoma (DLBCL) is one of the most common types of aggressive lymphoid malignancies. Here, we explore the contribution of RNA editing to DLBCL pathogenesis. We observed that DNA mutations and RNA editing events are often mutually exclusive, suggesting that tumors can modulate pathway outcomes by altering sequences at either the genomic or the transcriptomic level. RNA editing targets transcripts within known disease-driving pathways such as apoptosis, p53 and NF-kappa B signaling, as well as the RIG-I-like pathway. In this context, we show that ADAR1-mediated editing within MAVS transcript positively correlates with MAVS protein expression levels, associating with increased interferon/NF-kappa B signaling and T cell exhaustion. Finally, using targeted RNA base editing tools to restore editing within MAVS 3 ' UTR in ADAR1-deficient cells, we demonstrate that editing is likely to be causal to an increase in downstream signaling in the absence of activation by canonical nucleic acid receptor sensing.
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| 8. |
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| 9. |
- Saccullo, Michael, 1984
(författare)
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Alcohol Flexible Dual-Fuel Direct Injection Engine
- 2020
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Laws concerning emissions from HD internal combustion engines are becoming increasingly stringent in terms of local emissions and emissions concerning global warming such as lowering tailpipe CO2. New engine technologies are needed to satisfy these new requirements and to reduce fossil fuel dependency and increase renewable fuels in the transportation sector. One way to achieve both objectives can be to partially replace fossil fuels with alternatives that are sustainable with respect to emissions of greenhouse gases and engine out particulates. Also a decrease in NOx can be achieved. Suitable candidates are ethanol or methanol. The thesis presented here summarizes results from publications and additional results presented here with the aim to investigate the possible advantages of combusting low carbon alcohol fuels in dual-fuel configuration in a HD Diesel engine - in particular, the potential to greatly reduce particulate emissions and thereby bypass the soot-NOx tradeoff and lowering tailpipe CO2 emissions. It was complimented by additional results presented in the kappa itself. Ethanol sprays were studied in a high pressure/temperature spray chamber at typical engine condition with gas densities of about 27 kg/m^3 at around 550 C and around 60 bar. Spray parameters, such as the liquid cone angle, liquid penetration length and vapor penetration at injection pressures up to 2200 bar, were investigated. The characterization of those sprays was followed by an investigation focusing on the combustion of alcohol fuels in a single cylinder engine. Methanol, ethanol and E85 were chosen, but because of their poor auto-ignition properties, a pilot Diesel injection was used to initiate the combustion process. One of the alcohol fuels and Diesel were injected directly but separately, necessitating the use of two separate common rail systems together with a newly designed cylinder head and adapted injection nozzles. The dual fuel system's combustion properties were compared to those of pure Diesel with the same dual injection strategy. The injection pressure on the alcohol side were varied up to 2000 bar and investigations were carried out at low, medium and high speed-load points, with and without EGR. The investigated low carbon fuels outperformed Diesel under all tested conditions in terms of thermal efficiency and indicated specific NOx, soot and CO2 emissions. Thermal efficiency was increased by up to 3.5 %-points and simultaneously soot emissions were lowered by a factor of 40 or more and NOx by 20 %. ISCO2 emissions were down by up to 25 %. The fuel substitution ratio was over 95 % and the combustion stability was not compromised.
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| 10. |
- Saccullo, Michael, 1984, et al.
(författare)
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Alcohol flexible HD single cylinder diesel engine tests with separate dual high pressure direct fuel injection
- 2021
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Ingår i: Fuel. - : Elsevier BV. - 0016-2361. ; 294
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Tidskriftsartikel (refereegranskat)abstract
- Both greenhouse gas (GHG) emissions and local emissions from heavy duty (HD) Diesel engines must be greatly reduced to make transportation sustainable and comply with increasingly stringent emissions regulations. The fuel flexible engine concept for HD Diesel engines uses a dual fuel direct injection system in which ignition of the main alcohol fuel, either methanol or ethanol, is induced by a small Diesel pilot injection delivered via a separate direct injector. The objective of this investigation was to find ways to combine the advantages of conventional Diesel engines with the advantages of low carbon fuels and to thereby bypass the soot-NOx-trade-off. Experiments were conducted using a modified single-cylinder HD engine and three fuels (methanol, ethanol, and a reference Diesel fuel) to determine how the choice of fuel affected the engine's combustion behaviour, emissions and fuel efficiency. Injection pressures on the alcohol side were varied up to 1500 bar and the investigation was carried out at low, medium and high speed-load points. The alcohol fuels significantly outperformed Diesel fuel under all tested conditions (with and without exhaust gas recirculation (EGR)). Indicated thermal efficiency was increased by up to 3.5%-points and simultaneously soot emissions were lowered by a factor of 40 or more and NOx by 20%. Combustion stability and emissions were in the same range as for Diesel but replacing more than 95 % of the fossil Diesel with an alcohol fuel.
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