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Sökning: WFRF:(San Miguel J) > (2020-2024)

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  • De Larrea, CF, et al. (författare)
  • Primary plasma cell leukemia: consensus definition by the International Myeloma Working Group according to peripheral blood plasma cell percentage
  • 2021
  • Ingår i: Blood cancer journal. - : Springer Science and Business Media LLC. - 2044-5385. ; 11:12, s. 192-
  • Tidskriftsartikel (refereegranskat)abstract
    • Primary plasma cell leukemia (PCL) has a consistently ominous prognosis, even after progress in the last decades. PCL deserves a prompt identification to start the most effective treatment for this ultra-high-risk disease. The aim of this position paper is to revisit the diagnosis of PCL according to the presence of circulating plasma cells in patients otherwise meeting diagnostic criteria of multiple myeloma. We could identify two retrospective series where the question about what number of circulating plasma cells in peripheral blood should be used for defining PCL. The presence of ≥5% circulating plasma cells in patients with MM had a similar adverse prognostic impact as the previously defined PCL. Therefore, PCL should be defined by the presence of 5% or more circulating plasma cells in peripheral blood smears in patients otherwise diagnosed with symptomatic multiple myeloma.
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  • Barba-Lobo, Alejandro, 1992, et al. (författare)
  • Behavior of 222Rn, 220Rn and their progenies along a daily cycle for different meteorological situations: Implications on atmospheric aerosol residence times and Rn daughters' equilibrium factors
  • 2024
  • Ingår i: JOURNAL OF HAZARDOUS MATERIALS. - 0304-3894 .- 1873-3336. ; 464
  • Tidskriftsartikel (refereegranskat)abstract
    • The correct assessment of the radiological hazard from radon and daughters, external and internal doses, resi-dence times and equilibrium factors, implies the need to properly determine 222Rn (radon), 220Rn (thoron) and their respective short-lived progenies (214Pb and 214Bi, and 212Pb and 212Bi, respectively), where the precise measurements of both progenies are quite complex due to their very short half-lives. In addition, it is important to study the temporal behavior of all these radionuclides along daily cycles. Therefore, the aim of this study was to analyze the temporal evolution of radon, thoron and their progenies, and of their activity ratios along daily cycles for two different meteorological situations (synoptic and mesoscale processes). Radon and thoron were measured using a radon monitoring system, while their respective progenies were collected onto atmospheric filters using an ASS-500 sampler, and then measured by gamma-ray spectrometry. Furthermore, the different relationships between the concentrations of radionuclides and the different meteorological variables of interest (temperature, ABL height, and speed and direction of the wind) were found. Finally, the atmospheric aerosol residence times and Rn daughters' equilibrium factors were estimated for each sampling carried out along the two daily cycles, finding results consistent with previous studies.
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  • Resultat 1-10 av 23

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