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| 2. |
- Benmahi, B., et al.
(författare)
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Monitoring of the evolution of H2O vapor in the stratosphere of Jupiter over an 18-yr period with the Odin space telescope
- 2020
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 641
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Tidskriftsartikel (refereegranskat)abstract
- Context. The comet Shoemaker-Levy 9 impacted Jupiter in July 1994, leaving its stratosphere with several new species, with water vapor (H2O) among them. Aims. With the aid of a photochemical model, H2O can be used as a dynamical tracer in the Jovian stratosphere. In this paper, we aim to constrain the vertical eddy diffusion (Kzz) at levels where H2O is present. Methods. We monitored the H2O disk-averaged emission at 556.936 GHz with the space telescope between 2002 and 2019, covering nearly two decades. We analyzed the data with a combination of 1D photochemical and radiative transfer models to constrain the vertical eddy diffusion in the stratosphere of Jupiter. Results. Odin observations show us that the emission of H2O has an almost linear decrease of about 40% between 2002 and 2019. We can only reproduce our time series if we increase the magnitude of Kzz in the pressure range where H2O diffuses downward from 2002 to 2019, that is, from ~0.2 mbar to ~5 mbar. However, this modified Kzz is incompatible with hydrocarbon observations. We find that even if an allowance is made for the initially large abundances of H2O and CO at the impact latitudes, the photochemical conversion of H2O to CO2 is not sufficient to explain the progressive decline of the H2O line emission, which is suggestive of additional loss mechanisms. Conclusions. The Kzz we derived from the Odin observations of H2O can only be viewed as an upper limit in the ~0.2 mbar to ~5 mbar pressure range. The incompatibility between the interpretations made from H2O and hydrocarbon observations probably results from 1D modeling limitations. Meridional variability of H2O, most probably at auroral latitudes, would need to be assessed and compared with that of hydrocarbons to quantify the role of auroral chemistry in the temporal evolution of the H2O abundance since the SL9 impacts. Modeling the temporal evolution of SL9 species with a 2D model would naturally be the next step in this area of study.
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| 3. |
- Biver, N., et al.
(författare)
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Coma composition of comet 67P/Churyumov-Gerasimenko from radio-wave spectroscopy
- 2023
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 672
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Tidskriftsartikel (refereegranskat)abstract
- We present the results of a molecular survey of comet 67P/Churyumov-Gerasimenko undertaken with the Institut de RadioAstronomie Millimétrique (IRAM) 30-m radio telescope in November–December 2021, when it had its most favourable apparition in decades. Observations at IRAM 30-m during the 12–16 November period covered 8 GHz bandwidth at 3 mm, 16 GHz at 2 mm, and 60 GHz in the 1 mm window domain. These were completed by snapshots at 1 mm on 12–13 December and a short observation of the H2O line at 557 GHz with the Odin sub-millimetre observatory on 17.0 November 2021, and with 18-cm observations of OH with the Nançay radio telescope. Less sensitive observations obtained at a previous perihelion passage on 18–22 September 2015 with IRAM and 9–12 November 2015 with Odin are also presented. The gas outflow velocity, outgassing pattern, and temperature have been accurately constrained by the observations. They are perfectly consistent with those measured in situ with the Rosetta/MIRO sub-millimetre instrument in 2015. In particular, the asymmetry of the line is well represented by a jet concentrating three-quarters of the outgassing in about π steradians. We derived abundances relative to water for seven molecules and significant upper limits for approximately five others. The retrieved abundances were compared to those measured in situ at the previous perihelion with Rosetta. While those of HCN, CH3OH, and HNCO are comparable, 67P is found to be depleted in H2S and relatively normal in CS (H2S/CS ≈ 3) in strong contradiction with the Rosetta/ROSINA mass spectrometer measurement of the H2S/CS2 (≈100) abundance ratio. While the formaldehyde total abundance found with IRAM 30-m when assuming it to be mostly produced by a distributed source (Haser parent scale length ≈8000 km) is similar to the one derived by Rosetta/ROSINA, we find that the formaldehyde coming from the nucleus is one order of magnitude less abundant than measured in situ by Rosetta/ROSINA.
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| 4. |
- Mattsson, M., et al.
(författare)
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Validity and reliability of the Swedish version of the Self-Efficacy for Managing Chronic Disease scale for individuals with systemic sclerosis
- 2022
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Ingår i: Scandinavian Journal of Rheumatology. - : Informa UK Limited. - 0300-9742 .- 1502-7732. ; 51:2, s. 110-119
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveTo investigate aspects of validity and reliability of the Swedish version of the Self-Efficacy for Managing Chronic Disease (SEMCD-Swe) scale in systemic sclerosis (SSc).Method: A forward–backward translation procedure was used. Content validity was assessed through interviews with 11 people with SSc and 10 healthcare professionals. Construct validity, internal consistency, test–retest reliability, and floor and ceiling effects were evaluated in 104 SSc patients.Results: The content validity of the SEMCD-Swe was interpreted as satisfactory, but some adjustments were made to increase the understanding. Confirmatory factor analysis supported a single-factor structure. Moderate to strong correlations between the SEMCD-Swe and Scleroderma Health Assessment Questionnaire; Multidimensional Assessment of Fatigue; Patient Health Questionnaire-8 (rs = −0.4 to −0.7), and RAND-36 subscales (rs = 0.5 to 0.7) were found. Weak correlations were found between SEMCD-Swe and modified Rodnan skin score; and disease severity of peripheral vascular and lung (rs = −0.1 to −0.2) and kidney (rs = 0.1) systems (Medsger severity scale). Cronbach’s alpha was sufficient (0.85) and corrected item-to-total correlations were good (≥ 0.50). The intraclass correlation coefficient for the total score was sufficient (0.82). No floor or ceiling effects were found.Conclusion: Support for construct validity was indicated, as the SEMCD-Swe in SSc show a single-factor structure and is more strongly associated with pain, fatigue, depressive symptoms, interferences with daily activities, disability, and quality of life than with disease severity. Our results also indicate support for content validity and reliability. However, the responsiveness of the SEMCD-Swe needs to be tested.
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| 5. |
- Stromstad, Kine, et al.
(författare)
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Exploring return to work barriers through the lens of model of human occupation. The NOW WHAT project
- 2024
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Ingår i: Scandinavian Journal of Occupational Therapy. - : TAYLOR & FRANCIS LTD. - 1103-8128 .- 1651-2014. ; 31:1
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundThe challenges of returning to work after sickness absence demands a wide conceptual understanding of what hinders the employee's work participation. Thus, there is a need to know more about self-perceived barriers for Return to Work (RTW).AimThis study aimed to investigate RTW barriers experienced by employees on long-term sick leave, through the lens of the Model of Human Occupation (MOHO).Material and methodsThe study was a large-scale qualitative interview study (n = 85) using semi-structured telephone interviews. Eligible participants had received sick leave benefits for between 6 months and 1.5 years. The data were analysed with quantitative and qualitative content analysis. A deductive approach using the MOHO concepts guided the analysis process.ResultsThe study generated 941 coded meaning units describing barriers for RTW, of which we were able to code 895 within the framework of MOHO. In the person-specific concepts, performance capacity barriers were most often described (n = 303), followed by volitional barriers (n = 165) and barriers related to habituation (n = 66). Barriers related to the environmental components amounted to 361. Barriers in the occupational environment was dominant (n = 214).ConclusionExperienced barriers related to both environmental components and person-specific concepts.SignificanceThe habituational and volitional perspective on barriers can contribute to the identification and communication of performance capacity-related barriers not previously identified.
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| 6. |
- Xia, Zhi Jie, et al.
(författare)
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The Swedish COG6-CDG experience and a comprehensive literature review
- 2023
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Ingår i: JIMD Reports. - : Wiley. - 2192-8304 .- 2192-8312. ; , s. 79-89
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Here, we present the first two Swedish cases of Conserved Oligomeric Golgi complex subunit 6-congenital disorders of glycosylation (COG6-CDG). Their clinical symptoms include intellectual disability, Attention Deficit/Hyperactivity Disorder (ADHD), delayed brain myelinization, progressive microcephaly, joint laxity, hyperkeratosis, frequent infections, and enamel hypoplasia. In one family, compound heterozygous variants in COG6 were identified, where one (c.785A>G; p.Tyr262Cys) has previously been described in patients of Moroccan descent, whereas the other (c.238G>A; p.Glu80Lys) is undescribed. On the other hand, a previously undescribed homozygous duplication (c.1793_1795dup) was deemed the cause of the disease. To confirm the pathogenicity of the variants, we treated patient and control fibroblasts with the ER-Golgi transport inhibitor Brefeldin-A and show that patient cells manifest a significantly slower anterograde and retrograde ER-Golgi transport.
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