| 1. |
- Shao, D. W., et al.
(författare)
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Flow pattern, heat transfer and pressure drop in flow condensation part I : Pure and azeotropic refrigerants
- 2000
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Ingår i: HVAC & R RESEARCH. - : Informa UK Limited. - 1078-9669 .- 1938-5587. ; 6:2, s. 175-195
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Tidskriftsartikel (refereegranskat)abstract
- This study concerns the flow pattern, heat transfer, and pressure drop for flow condensation. The experimental results are recorded in tests with a smooth horizontal tube of 6 mm inner diameter and 2 to 10 m long. This manuscript, which is part I of a two part series, focuses on pure and azeotropic fluids. Part II describes results with non-azeotropic refrigerant mixtures. A flow pattern map by Tandon et al. (1982) roughly predicts flow patterns associated with pure and azeotropic fluids in this work. However, the Froude number is found to be a good additional indicator to identify transition between annular and wavy flows. The transition occurs mostly at Fr = 15 to 20 for both pure and azeotropic fluids. In the case of pure and azeotropic fluids, the hear transfer coefficient was found to be independent of the mass flux in wavy flow regions, but increased with an increasing mass flux in the annular flow regions. For pure and azeotropic fluids, a modified Tandon et al. correlation agreed best with experimental data from tests with R-12, R-22, R-134a, and R-502. For the local pressure drop it is correlated within +/-15% by using the Lockhart-Martinelli parameters. The experimental data for pure and azeotropic refrigerants can be predicted by using a correlation for overall pressure drop.
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| 2. |
- Shao, D. W., et al.
(författare)
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Flow pattern, heat transfer and pressure drop in flow condensation part II : Zeotropic refrigerants mixtures (NARMs)
- 2000
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Ingår i: HVAC & R RESEARCH. - : Informa UK Limited. - 1078-9669 .- 1938-5587. ; 6:2, s. 197-209
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Tidskriftsartikel (refereegranskat)abstract
- This paper, which is parr II of a study on flow condensation is focused on zeotropic (or non-azeotropic) refrigerant mixtures (NARMs) In the experiments, condensation in a horizontal tube of inner diameter 6 mm and 10 m length were studied with fluids R-404A, R-407C, and three mixtures of R-32 and R-134a. A flow pattern map by Tandon et al. (1982) roughly predicts flow patterns associated with NARMs studied in this work. Most tests recorded are in the annular or semi annular flow region. The Froude number is, however, found to be an additional indicator to identify transition between annular and wavy flows. The transition in the experiments occurs mostly at Fr = 15 to 20 for the fluids tested. For NARMs with a small temperature glide (e.g. R-404A), as observed in the case of pure and azeotropic fluids, the hear transfer coefficient is independent of the mass flux in wavy flow regions, and increases with an increasing mass flux in annular flow regions. For other NARMs tested, the hear transfer coefficient (starting from a lower level) always increases with an increasing mass flux within the tested ranges. The heat transfer data from the tests with R-404A, R-407C, and R-32/R-134a mixtures can be predicted reasonably well by a modified Tandon et al. (1985b, 1995) equation with a correction proposed by Granryd (1989)for NARMs. The classical correlations for the pressure drop do nor work well. Instead, the data for local pressure drop are correlated within +/-15% by means of the same correlation as for the pure and azeotropic fluids. A simple correlation for the overall pressure drop based on the experimental data for pure and azeotropic fluids is good also for R-404A (with a small glide), but overpredicts the pressure drop (by up to 50%)for NARMs with glide, such as R-407C.
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| 3. |
- Shao, X-W, et al.
(författare)
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Application of a colorimetric chain-termination assay for characterization of reverse transcriptase from 3-azido-2,3-deoxythymidine-resistant HIV isolates
- 2002
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Ingår i: Biotechnology and applied biochemistry. - 0885-4513 .- 1470-8744. ; 35, s. 155-164
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Tidskriftsartikel (refereegranskat)abstract
- wo different enzyme assays, both based on the interaction of native reverse transcriptase(IRT) and 3'-azido-2',3'-deoxythymidine triphosphate (AZT-TP), were used to characterize the enzymesfrom 18 HIV-I isolates with decreased sensitivity to AZT in cell culture. The first assay, which measures the balance between incorporation and excision of AZT monophosphate in the presence of dNTP substrate (in terms of IC50), gave an approx. 9-fold variation in sensitivity to AZT-TP. There was a correlation between the IC50 values and the sensitivity of the corresponding virus to AZT in cell culture (r = 0.60, P < 0.01). The second assay, which was designed specifically for measurement of chain termination in the absence of dNTP substrate (as the concentration of AZT-TP giving 50% residual primer function, or CT50), revealed a more than 600-fold difference between the different isolate RTs. For the majority ofenzymes there was a strict correlation between the results from the two assays; however, four isolatesexhibited significantly higher CT50/IC50 ratios than the other isolates. These differences were not related to sensitivity of the corresponding viruses to AZT but to the occurrence of certain mutations in their pol gene. The four deviating isolates contained either a minimum of four AZT-specific substitutions, including Thr-215 --> Tyr (isolates 134 and 143), or some of the known specific substitutions combined with Thr-39 --> Ala (isolates 80 and 157). The Thr-39 Ala substitution has previously been recorded in connection with AZT/Foscarnet combination therapy.
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| 4. |
- Zhang, X. L., et al.
(författare)
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Automatic real-time control for gain-flattened fiber Raman amplifiers
- 2004
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Ingår i: Optics Communications. - : Elsevier BV. - 0030-4018 .- 1873-0310. ; 239:01-3, s. 79-84
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Tidskriftsartikel (refereegranskat)abstract
- An automatic control algorithm for flattening the gain of a fiber Raman amplifier is derived from the Raman scattering equations. A pseudo-inverse gain matrix is introduced to adjust the powers of the pump lasers. The algorithm is simple, fast, effective, robust and insensitive to the length and type of the fiber. It is demonstrated experimentally that the gain flattening for Raman amplifiers comprising various types and lengths of fiber and with different target gains can be achieved automatically with this algorithm. The algorithm converges for both small and large input signal. Flattened Raman gain with a fluctuation less than 0.40 dB over a 50-nm bandwidth for a 50-km SMF or less than 0.20 dB over a 40-nm bandwidth for a 6.6-km dispersion compensated fiber is realized in the experiment.
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