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- Bousquet, J, et al.
(författare)
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Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper
- 2012
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Ingår i: International archives of allergy and immunology. - : S. Karger AG. - 1423-0097 .- 1018-2438. ; 158:3, s. 216-231
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Tidskriftsartikel (refereegranskat)abstract
- Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies.
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- Danielsson, Ulf H., et al.
(författare)
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De Sitter hunting in a classical landscape
- 2011
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Ingår i: Fortschritte der Physik. - : Wiley. - 0015-8208 .- 1521-3978. ; 59:9
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Tidskriftsartikel (refereegranskat)abstract
- We elaborate on the construction of de Sitter solutions from IIA orientifolds of SU(3)-structure manifolds that solve the 10-dimensional equations of motion at tree-level in the approximation of smeared sources. First we classify geometries that are orbifolds of a group manifold covering space which, upon the proper inclusion of O6 planes, can be described within the framework of N=1 supergravity in 4D. Then we scan systematically for de Sitter solutions, obtained as critical points of an effective 4D potential. Apart from finding many new solutions we emphasize the challenges in constructing explicit classical de Sitter vacua, which have sofar not been met. These challenges are interesting avenues for further research and include finding solutions that are perturbatively stable, satisfy charge and flux quantization, and have genuine localized (versus smeared) orientifold sources. This paper intends to be self-contained and pedagogical, and thus can serve as a guide to the necessary technical tools required for this line of research. In an appendix we explain how to study flux and charge quantization in the presence of a non-trivial H-field using twisted homology.
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- Mortazavi, MM, et al.
(författare)
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The ventricular system of the brain : a comprehensive review of its history, anatomy, histology, embryology, and surgical considerations
- 2014
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Ingår i: Child's nervous system (Print). - : Springer Science and Business Media LLC. - 0256-7040 .- 1433-0350. ; 30:1, s. 19-35
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Forskningsöversikt (refereegranskat)abstract
- The cerebral ventricles have been recognized since ancient medical history. Their true function started to be realized more than a thousand years later. Their anatomy and function are extremely important in the neurosurgical panorama. The literature was searched for articles and textbooks of different topics related to the history, anatomy, physiology, histology, embryology and surgical considerations of the brain ventricles. Herein, we summarize the literature about the cerebral ventricular system.
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- Nilsson, Anna-Lena, 1959-, et al.
(författare)
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A Prescription for Change : Report on EU Healthcare Provision for Deaf Sign Language Users.
- 2013
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- During 2010-2012, a Leonardo da Vinci-funded EU project focused on enhancing the language skills of Deaf people, interpreters and Health Care Professionals. Project partners from Cyprus, Ireland, Poland, Scotland and Sweden reviewed current knowledge of policy and practice, and embedded the resulting analysis into a programme of materials to support reflection, knowledge and skills development internationally. This report presents the project's initial 'state-of-the-art' review, with particular reference to the partner countries.
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