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Träfflista för sökning "WFRF:(Sheng Xin) srt2:(2010-2014)"

Sökning: WFRF:(Sheng Xin) > (2010-2014)

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1.
  • Haiman, Christopher A., et al. (författare)
  • A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer
  • 2011
  • Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 43:12, s. 61-1210
  • Tidskriftsartikel (refereegranskat)abstract
    • Estrogen receptor (ER)-negative breast cancer shows a higher incidence in women of African ancestry compared to women of European ancestry. In search of common risk alleles for ER-negative breast cancer, we combined genome-wide association study (GWAS) data from women of African ancestry (1,004 ER-negative cases and 2,745 controls) and European ancestry (1,718 ER-negative cases and 3,670 controls), with replication testing conducted in an additional 2,292 ER-negative cases and 16,901 controls of European ancestry. We identified a common risk variant for ER-negative breast cancer at the TERT-CLPTM1L locus on chromosome 5p15 (rs10069690: per-allele odds ratio (OR) = 1.18 per allele, P = 1.0 x 10(-10)). The variant was also significantly associated with triple-negative (ER-negative, progesterone receptor (PR)-negative and human epidermal growth factor-2 (HER2)-negative) breast cancer (OR = 1.25, P = 1.1 x 10(-9)), particularly in younger women (<50 years of age) (OR = 1.48, P = 1.9 x 10(-9)). Our results identify a genetic locus associated with estrogen receptor negative breast cancer subtypes in multiple populations.
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2.
  • Shaoyang, Zhang, et al. (författare)
  • Image enhancement on fractional differential for road traffic and aerial images under bad weather and complicated situations
  • 2014
  • Ingår i: Transportation letters. - 1942-7867 .- 1942-7875. ; 6:4, s. 197-205
  • Tidskriftsartikel (refereegranskat)abstract
    • To enhance road traffic images and aerial images in bad weather, a new fractional differential operator is studied, and it is different from the traditional Tiansi operator. In the operator, for any sized kernel, the coefficient at the center position is not a constant, and it is the function of the fractional order and the kernel size; for the other pixels in the kernel, there is no zero coefficient value, and the values of the coefficients are calculated according to the distances from the center position on the basis of fractional differential. In experiments, a number of images are tested, and the results show that the studied operator is suitable for the vague images of the low contrast and rich textures, with less color changes. When compared with other newly proposed algorithms (e.g. Dark channel prior and Multiple scale Retinex, etc.) it performs better in some cases.
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