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| 2. |
- Matheu, Victor, et al.
(författare)
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Lupine-induced anaphylaxis
- 1999
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Ingår i: Annals of Allergy, Asthma & Immunology. - 1081-1206. ; 83:5, s. 406-408
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Legumes are one of the most common foods causing allergic reactions in children and adults. Cross-reacting antibodies are frequently demonstrated in this family but the real clinical cross-reactivity is uncommon. OBJECTIVE: To report a case of lupine-induced anaphylaxis and to elucidate in vivo and in vitro cross-reactivity with some legumes. METHODS: Skin prick test (SPT) with some legumes were performed. Cap-IgE, ELISA-IgE, and immunoblotting were carried out. Open oral challenges with some legumes were performed. Cross-reactivity was studied by ELISA and immunoblotting inhibition. RESULTS: The results demonstrated type-I hypersensitivity reactions with lupine and some other legumes. Cap-IgE with peanut was positive but the SPT and ELISA-IgE were negative and the patient tolerated a peanut challenge. ELISA inhibition revealed a partial inhibition (62%) using lupine as the solid phase. Partial inhibition was demonstrated by immunoblotting inhibition. Open oral challenge with peanut and green bean were negative but positive with pea. CONCLUSION: We present a lupine sensitized patient with positive SPT and in vitro cross-reactivity with other legumes. Clinical cross-reactivity progressively developed over a 5-year period. Discrepancies were found between the clinical aspect and in vitro study of peanut allergy. Factors determining the wide variability in cross-reactivity among individuals are still obscure.
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| 3. |
- De Barrio, M, et al.
(författare)
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Fixed drug eruption induced by indapamide. Cross-reactivity with sulfonamides
- 1998
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Ingår i: Journal of Investigational Allergology & Clinical Immunology. - 1698-0808. ; 8:4, s. 253-255
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Tidskriftsartikel (refereegranskat)abstract
- Indapamide is a nontiazidic sulfonamide diuretic which has not been previously reported as a cause of fixed drug eruption. We describe a patient who experienced several episodes of fixed drug eruption during treatment with indapamide. The diagnosis was confirmed by positive controlled oral challenge test. The possible existence of cross-reactivity with other sulfonamide derivatives was investigated by controlled oral challenge test with sulfamethoxazole, sulfadiazine and furosemide, with the tests with sulfamethoxazole and sulfadiazine resulting positive.
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| 4. |
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| 5. |
- Sierra, ML, et al.
(författare)
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Mixed micelles containing alkylglycosides: Effect of the chain length and the polar head group
- 1999
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Ingår i: Langmuir. - 0743-7463 .- 1520-5827. ; 15, s. 2301-2306
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Tidskriftsartikel (refereegranskat)abstract
- The mixing behavior of binary mixtures of the pure alkylglycosides: -decylglucoside (-C10G), -dodecylglucoside (-C12G), -decylmaltoside (-C10M), and dodecylmaltoside (C12M) in combination with different common surfactants has been studied. First, the effect of the nonionic polar headgroup and chain length of the glycosidic surfactants in the mixed micellization with sodium dodecyl sulfate (SDS) was investigated. Further on, to analyze the effect of the ionic headgroup on the micellization of the glycosidic surfactant, -C10G was mixed with different surfactants: dodecyltrimethylammonium bromide (DTAB), dodecylheptaethylene glycol ether (C12E7), and -C10M. All the mixed systems under study adapt reasonably well to the model developed by Rubingh, with negative values for the interaction parameter, m, indicating a favorable interaction between the mixed surfactants. In the mixtures with SDS and the glycosides, the interactions become stronger when the hydrocarbon chain length of the surfactant is shorter and the hydrophilic headgroup is larger, i.e., when the surfactants become more hydrophilic. The -C10G mixes favorably with the other surfactants, the interaction becoming stronger in the order C12E7, -C10M, SDS, DTAB. The strong interaction in micellization with DTAB is explained by assuming an anionic character in the -C10G molecule, as shown by electroosmosis measurements. Finally, the favorable interaction with -C10M is explained by considering the packing between the headgroups of both nonionic surfactants.
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