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- Etter, Sarah B., et al.
(författare)
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Spontaneous surface flux pattern in chiral p-wave superconductors
- 2018
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Ingår i: Physical Review B. - : AMER PHYSICAL SOC. - 2469-9950 .- 2469-9969. ; 97:6
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Tidskriftsartikel (refereegranskat)abstract
- In chiral p-wave superconductors, magnetic flux patterns may appear spontaneously when translational symmetry is broken such as at surfaces, domain walls, or impurities. However, in the candidate material Sr2RuO4 no direct signs of such magnetic fields have been detected experimentally. In this paper, the flux pattern at the edge of a disk-shaped sample is examined using the phenomenological Ginzburg-Landau approach. The detailed shape of the flux pattern, including self-screening, is computed numerically for different surface types by systematically scanning a range of boundary conditions. Moreover, specific features of the electronic structure are included qualitatively through the coefficients in the Ginzburg-Landau functional. Both the shape and the magnitude of the flux pattern are found to be highly sensitive to all considered parameters. In conclusion, such spontaneous magnetic flux patterns are not a universal feature of chiral p-wave superconductors.
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| 2. |
- Kaegi-Braun, Nina, et al.
(författare)
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Validation of modified GLIM criteria to predict adverse clinical outcome and response to nutritional treatment : A secondary analysis of a randomized clinical trial
- 2022
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Ingår i: Clinical Nutrition. - : Elsevier. - 0261-5614 .- 1532-1983. ; 41:4, s. 795-804
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Tidskriftsartikel (refereegranskat)abstract
- Background & aims: The Global Leadership Initiative on Malnutrition (GLIM) recently suggested specific criteria to standardize the diagnosis of malnutrition. There is need for validation of these criteria regarding response to nutrition treatment. Our aim was to validate modified GLIM (mGLIM) criteria among medical inpatients at risk of disease related malnutrition for prediction of outcome and response to nutritional therapy.Methods: This is a secondary analysis of the Effect of Early Nutritional Support on Frailty, Functional Outcomes, and Recovery of Malnourished Medical Inpatients Trial (EFFORT), a multicenter randomized controlled trial conducted between April 2014 and February 2018. Adult medical inpatients at nutritional risk (Nutrition Risk Score 2002 > 3 points) were randomly assigned to receive nutritional therapy according to an algorithm based on individualized nutritional requirements (intervention group) or standard hospital food (control group). We included all participants with available information regarding mGLIM criteria. The primary outcome was adverse clinical outcome, which was a composite of 30-day all-cause mortality, ICU-admission, rehospitalization rate, major complications and decline in functional status.Results: Of 1917 eligible participants at nutritional risk, 1181 (61.6%) met the diagnosis of malnutrition based on mGLIM criteria. The incidence of adverse clinical outcome was significantly higher in mGLIMpositive participants compared with mGLIM-negative participants [330/1181 (27.9%) versus 140/736 (19.0%); multivariable adjusted odds ratio [OR] 1.53; 95% CI 1.22-1.93; p < 0.001]. Regarding the effect of nutritional therapy, the reduction in adverse clinical outcomes was higher in mGLIM-positive participants [180/581 (31.0%) vs. 150/600 (25.0%), OR 0.69; 95% CI 0.53-0.9, p = 0.007], compared with mGLIMnegative participants [75/379 (19.8%) versus 65/357 (18.2%), OR 0.95; 95% CI 0.65-1.40, p = 0.797], a finding that was, however, not significant in interaction analysis (p for interaction = 0.217).Conclusion: Data from this secondary analysis of a multicenter randomized trial involving medical inpatients at nutritional risk validate the strong prognostic value of mGLIM criteria regarding adverse clinical outcomes and other long-term outcomes. However, further research is needed to improve the ability of GLIM criteria to predict therapeutic response to nutritional interventions.Trial registration: ClinicalTrials.gov Identifier: NCT02517476.
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