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- Amaral, L., et al.
(författare)
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Disentangling hand and tool processing: Distal effects of neuromodulation
- 2022
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Ingår i: Cortex. - : Elsevier BV. - 0010-9452. ; 157, s. 142-154
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Tidskriftsartikel (refereegranskat)abstract
- Neural processing within a local brain region that responds to more than one object category (e.g., hands and tools) nonetheless have different functional connectivity patterns with other distal brain areas, which suggests that local processing can affect and/or be affected by processing in distal areas, in a category-specific way. Here we wanted to test whether administering either a hand-or tool-related training task in tandem with trans -cranial direct current stimulation (tDCS) to a region that responds both to hands and tools (posterior middle temporal gyrus; pMTG), modulated local and distal neural processing more for the trained than the untrained category in a subsequent fMRI task. After each combined tDCS/training session, participants viewed images of tools, hands, and animals, in an fMRI scanner. Using multivoxel pattern analysis, we found that tDCS stimulation to pMTG indeed improved the classification accuracy between tools vs. animals, but only when combined with a tool and not a hand training task. Surprisingly, tDCS stimulation to pMTG also improved classification accuracy between hands vs. animals when combined with a tool but not a hand training task. Our findings suggest that overlapping but functionally-specific networks may be engaged separately by using a category-specific training task together with tDCS -a strategy that can be applied more broadly to other cognitive domains using tDCS. By hypothesis, these effects on local processing are a direct result of within-domain connectivity constraints from domain-specific networks that are at play in the processing and organization of object representations.(c) 2022 Elsevier Ltd. All rights reserved.
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| 2. |
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| 3. |
- Simeth, M., et al.
(författare)
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Losing talent by partnering up? : The impact of R&D collaboration on employee mobility
- 2022
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Ingår i: Research Policy. - : Elsevier BV. - 0048-7333 .- 1873-7625. ; 51:7
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Tidskriftsartikel (refereegranskat)abstract
- Firms frequently enter collaborations with other organizations for the purpose of innovating. In this paper, we argue that engaging in R&D collaboration can have the unintended consequence of increasing the mobility of highly skilled personnel. We investigate our research question using a representative dataset that combines information from the Swedish Community Innovation Survey (CIS) with employer–employee registry data. Our econometric analysis shows that R&D collaborations by firms are associated with higher levels of outgoing mobility among skilled employees, particularly among those with technical (“STEM”) education and master's or doctoral degrees. We also find support for the interpretation that R&D collaboration augments employees’ general human capital, subsequently increasing their outside employment options. We discuss important implications for firm collaboration strategies.
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| 4. |
- Sott, Richard, 1974, et al.
(författare)
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Mixed complexes formed by lithioacetonitrile and chiral lithium amides: observation of (6)li,(15)N and (6)Li,(13)C couplings due to both C-Li and N-Li contacts.
- 2004
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Ingår i: Journal of the American Chemical Society. - : American Chemical Society (ACS). - 0002-7863 .- 1520-5126. ; 126:21, s. 6798-805
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Tidskriftsartikel (refereegranskat)abstract
- NMR spectroscopic studies have been performed on the mixed complexes formed by the lithium salt of acetonitrile (LiCH(2)CN) and the chiral lithium amides Li-(S)-N-(2-methoxybenzyl)-1-amino-1-phenyl-2-ethoxyethane (Li-1) and Li-(S)-N-isopropyl-2-amino-1-phenyl-3-methoxypropane (Li-2) in diethyl ether and tetrahydrofuran solvent. In diethyl ether Li-1 and LiCH(2)CN form a mixed dimeric (1:1) complex, while Li-2 and LiCH(2)CN form a mixed trimeric (2:1) complex. The dimer undergoes fast exchange between ketenimine and bridged structures. Both (1)J((15)N,(6)Li) and (1)J((13)C,(6)Li) couplings were observed for the respectively isotopically labeled compounds. In the trimeric complex the CH(2)CN anion also undergoes fast degenerate exchange between ketenimine and bridged structures, and the complex appears C(2)-symmetric on the NMR spectroscopy time scale. Both the dimer and trimer complexes have the bridged acetonitrile anion in common, as indicated by the highly shielded alpha-carbon (13)C NMR shifts (delta -6.1 and -7.4, respectively). In tetrahydrofuran only N-metalated mixed LiCH(2)CN dimers were observed for both Li-1 and Li-2 with the less shielded (13)C NMR shifts of delta -2.5 and -2.2 for the alpha-carbon of LiCH(2)CN of the complexes.
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