| 1. |
- Gallo, Katia, et al.
(författare)
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Buried slab waveguides in LiNbO3 nonlinear photonic crystals
- 2005
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Ingår i: Proceedings of WFOPC 2005. - 0780389492 ; , s. 36-40
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Konferensbidrag (refereegranskat)abstract
- We present an efficient integrated device for SHG at telecom wavelengths in Hexagonally Poled LiNbO3, based on the reverse proton exchange waveguide technology. We discuss its nonlinear response in terms of power, wavelength and angle tunability and use the experimental SHG data to infer also information on the linear properties of the waveguide.
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| 2. |
- Gallo, Katia, et al.
(författare)
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Guided-wave second-harmonic generation in a LiNbO3 nonlinear photonic crystal
- 2006
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Ingår i: Optics Letters. - 0146-9592 .- 1539-4794. ; 31:9, s. 1232-1234
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Tidskriftsartikel (refereegranskat)abstract
- We demonstrate twin-beam second-harmonic generation from telecommunications wavelengths in an optimized buried reverse proton exchanged planar waveguide made in 2D hexagonally poled LiNbO3. Experiments carried out with a nanosecond narrow-bandwidth, high-power fiber source thoroughly explored the response of the nonlinear photonic crystal device in terms of its power, wavelength, and angle tunability.
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| 3. |
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| 4. |
- Gianoukakis, Andrew G., et al.
(författare)
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Hyaluronan accumulation in thyroid tissue : evidence for contributions from epithelial cells and fibroblasts
- 2007
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Ingår i: Endocrinology. - : The Endocrine Society. - 0013-7227 .- 1945-7170. ; 148:1, s. 54-62
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Tidskriftsartikel (refereegranskat)abstract
- Graves' disease (GD) and Hashimoto's thyroiditis (HT) are autoimmune processes often associated with hyperthyroidism and hypothyroidism, respectively. Despite their diverging clinical presentations, immune activation drives both diseases and results in connective tissue accumulation of the nonsulfated glycosaminoglycan, hyaluronan. The hydrophilic property of hyaluronan contributes to the pathogenesis of thyroid-associated ophthalmopathy, dermopathy and hypothyroid myxedema. Whether hyaluronan accumulates in the thyroid and plays a role in goiter formation in GD and HT remains unknown. We report here that levels of hyaluronan are increased in thyroid tissue from individuals with both diseases compared with glands uninvolved with autoimmune disorders. The transcript encoding hyaluronan synthase (HAS)-3, one of three mammalian HAS isoforms, was detected in thyroid tissue. Isolated thyrocytes in primary culture express all three HAS isoforms when treated with IL-1beta. Thyrocytes and thyroid fibroblasts produce hyaluronan under basal culture conditions and IL-1beta enhances levels of this molecule in both cell types. On a per-cell basis, fibroblasts produce more hyaluronan than do thyrocytes under basal conditions and after cytokine treatment. Synthesis in thyrocytes can also be altered by increasing serum concentration in the medium and by modifying culture density. Our findings suggest that hyaluronan accumulation in thyroid tissue might derive from thyrocytes and fibroblasts. Moreover, this glycosaminoglycan becomes more abundant as a consequence of autoimmune disease. It may therefore contribute to increased thyroid volume in GD and HT. Coupled with the newly identified influence exerted by hyaluronan on immunocompetent cells, our findings represent potentially important insights into the pathogenesis of autoimmune thyroid diseases.
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| 5. |
- Papageorgiov, Christos, 1975-, et al.
(författare)
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Experimental Testing and Modelling of a Passive Mechanical Steering Compensator for High-Performance Motorcycles
- 2007
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Ingår i: Proceedings of the '07 European Control Conference.
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Konferensbidrag (refereegranskat)abstract
- This paper presents experimental results and a modelling study of a prototype mechanical device that represents a novel steering compensator for high-performance motorcycles. The mechanical device is different from conventional damper devices since it has been designed to represent a series combination of a damper and an inerter. The ideal inerter is a one-port mechanical element which is the exact analogue of the capacitor under the force-current analogy between mechanical and electrical networks, so that the force (torque) through the device is proportional to the relative acceleration (angular acceleration) across its terminals. The steering compensator is tested on a hydraulic test rig and the experimental admittance of the device is calculated over a specified frequency range. A model of the device is developed, including parasitic effects and nonlinearities, which achieves a good fit between model and experimental data.
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