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Sökning: WFRF:(Solá Miguel) > (2020-2023)

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  • Pinto, Ana Margarida, et al. (författare)
  • Emotion regulation and the salience network : a hypothetical integrative model of fibromyalgia
  • 2023
  • Ingår i: Nature Reviews Rheumatology. - : Springer Nature. - 1759-4790 .- 1759-4804. ; 19:1, s. 44-60
  • Tidskriftsartikel (refereegranskat)abstract
    • Fibromyalgia is characterized by widespread pain, fatigue, sleep disturbances and other symptoms, and has a substantial socioeconomic impact. Current biomedical and psychosocial treatments are unsatisfactory for many patients, and treatment progress has been hindered by the lack of a clear understanding of the pathogenesis of fibromyalgia. We present here a model of fibromyalgia that integrates current psychosocial and neurophysiological observations. We propose that an imbalance in emotion regulation, reflected by an overactive 'threat' system and underactive 'soothing' system, might keep the 'salience network' (also known as the midcingulo-insular network) in continuous alert mode, and this hyperactivation, in conjunction with other mechanisms, contributes to fibromyalgia. This proposed integrative model, which we term the Fibromyalgia: Imbalance of Threat and Soothing Systems (FITSS) model, should be viewed as a working hypothesis with limited supporting evidence available. We hope, however, that this model will shed new light on existing psychosocial and biological observations, and inspire future research to address the many gaps in our knowledge about fibromyalgia, ultimately stimulating the development of novel therapeutic interventions.
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  • Sytcevich, Ivan, et al. (författare)
  • Characterizing ultrashort laser pulses with second harmonic dispersion scans
  • 2021
  • Ingår i: Journal of the Optical Society of America B: Optical Physics. - 0740-3224. ; 38:5, s. 1546-1555
  • Forskningsöversikt (refereegranskat)abstract
    • The dispersion scan (d-scan) technique has emerged as a simple-to-implement characterization method for ultrashort laser pulses. D-scan traces are intuitive to interpret and retrieval algorithms that are both fast and robust have been developed to obtain the spectral phase and the temporal pulse profile. Here, we shortly review the second harmonic generation d-scan technique, focusing predominantly on results obtained at the Lund Laser Centre.We describe and compare recent implementations for the characterization of few- and multi-cycle pulses as well as two different approaches for recording d-scan traces in a single shot, thus showing the versatility of the technique.
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  • Resultat 1-4 av 4

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