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Träfflista för sökning "WFRF:(Stegmayr Bernd) ;srt2:(2005-2009)"

Search: WFRF:(Stegmayr Bernd) > (2005-2009)

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  • Stegmayr, Christoffer, et al. (author)
  • Hemodialysis dialyzers contribute to contamination of air microemboli that bypass the alarm system in the air trap.
  • 2008
  • In: International Journal of Artificial Organs. - 0391-3988 .- 1724-6040. ; 31:4, s. 317-22
  • Journal article (peer-reviewed)abstract
    • BACKGROUND: Previous studies have shown that micrometer-sized air bubbles are introduced into the patient during hemodialysis. The aim of this study was to investigate, in vitro, the influence of dialysis filters on the generation of air bubbles. METHODS: Three different kind of dialyzers were tested: one high-flux FX80 dry filter (Fresenius Medical Care AG&Co. KGaA, Bad Homburg, Germany), one low-flux F8HPS dry filter (Fresenius Medical Care AG&Co. KGaA, Bad Homburg, Germany) and a wet-stored APS-18u filter (Asahi Kasei Medical, Tokyo, Japan). The F8HPS was tested with pump flow ranging between 100 to 400 ml/min. The three filters were compared using a constant pump flow of 300 ml/min. Measurements were performed using an ultrasound Doppler instrument. RESULTS: In 90% of the series, bubbles were measured after the outlet line of the air trap without triggering an alarm. There were significantly more bubbles downstream than upstream of the filters F8HPS and FX80, while there was a significant reduction using the APS-18u. There was no reduction in the number of bubbles after passage through the air trap versus before the air trap (after the dialyzer). Increased priming volume reduced the extent of bubbles in the system. CONCLUSIONS: Data indicate that the air trap does not prevent air microemboli from entering the venous outlet part of the dialysis tubing (entry to the patient). More extended priming of the dialysis circuit may reduce the extent of microemboli that originate from dialysis filters. A wet filter may be favorable instead of dry-steam sterilized filters.
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  • Holmberg, Benny, et al. (author)
  • Cardiovascular conditions in hemodialysis patients may be worsened by extensive interdialytic weight gain
  • 2009
  • In: Hemodialysis International. - : Wiley. - 1492-7535 .- 1542-4758. ; 13:1, s. 27-31
  • Journal article (peer-reviewed)abstract
    • The risk of death is increased for hemodialysis (HD) patients compared with age-matched healthy subjects, the main reason for this being cardiovascular conditions. This prospective study investigated whether the burden of interdialytic weight gain (IDWG) was of importance for cardiovascular end points and survival. A total of 97 HD patients were studied. The end points included death (reasons given), acute myocardial infarction, or coronary vascular intervention. The extent of ultrafiltration was measured at predefined follow-up points. The IDWG was calculated as ultrafiltration/body weight given in weight%. The burden of IDWG was analyzed. End points occurred in 77 (79%) of the patients during the 5-year study period. The extent of IDWG was higher in those with end points due to cardiovascular reasons (3.77 weight% vs. 3.19 P<0.001), cardiac reasons (P<0.001), congestive heart failure (P<0.01), aortic aneurysm, and intracerebral bleeding (P<0.024). To reduce the risk for cardiovascular events, it is important to avoid too extensive IDWG in HD patients.
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  • Result 1-10 of 42

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