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- Bolmsvik, Åsa, 1975-, et al.
(författare)
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Vibration Distribution Due to Continous, Intermittent or Half Embedded Elastomer Connections in Wooden Constructions
- 2016
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Ingår i: Proceeding of the 2016 World Conference on Timber Engineering (WCTE), August 22-25, 2016 Vienna. - Vienna : TU-MV Media Verlag. - 9783903039001 - 9783903024359 ; , s. 2912-2920
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Konferensbidrag (refereegranskat)abstract
- Elastomers are commonly used to decrease the sound transmission between apartments in timber framed houses. In previous studies, different types of elastomers have been evaluated experimentally. The wooden assemblies, in which elastomers were used in the connections, showed that elastomers cause the vibrations to increase in the direction perpendicular to the applied load within the low frequency span.In this study, the effects on acceleration, depending on how the elastomers are placed are studied. The cases having the elastomer continuous, placed as intermittent pieces or positioned half embedded in the junctions are evaluated.The frequency dependent properties of the elastomers are needed in order to model the dynamic behaviour and thereby be able to predict sound- and vibration transmission in wooden houses. Here, the properties of a wooden construction having different elastomers connections are studied to enable simulations of the behaviour of the elastomers in a FE model in the future.
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| 2. |
- Picha Edwardsson, Malin, 1970-
(författare)
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Towards a sustainable media system : Explorative studies of emerging media consumption trends and media processes for content production
- 2015
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Understanding the process of transformational change currently taking place in the media industry is an urgent challenge for people working in the industry as well as for media consumers and other stakeholders. There is a great need to deepen our general knowledge when it comes to what the future media landscape will look like. Which of the major consumption trends that exist today will continue and possibly lead to disruptive change? Which of today’s existing trends could give us a hint of tomorrow’s media landscape? Furthermore, we need to explore the environmental impact of the future media landscape. What parameters are important when it comes to environmental aspects of media consumption, as well as in the production and distribution of media content? These are examples of the questions explored in this thesis.I have used a number of methods, such as qualitative interviews, workshops, scenarios, case studies, process studies and life cycle assessment, in order to explore the research questions. The characteristics of the media consumption trends are presented in four scenarios. I have assumed that the strength of influence from the government in combination with the strength of commercial powers will strongly affect the future of media. The development of media is framed by the economy, the political system, and by culture. The future of media is closely connected with its relationship to the power structures in society.I have also defined eleven parameters, as central when discussing the environmental aspects of media consumption. These parameters are related to electronic devices, travel, transportation, energy use and waste. In the future, we may see the realisation of some of all four scenarios described in this thesis. The environmental aspects of these different future directions depend on each person’s life situation and a number of choices that each consumer makes concerning environmental issues, in combination with the overall societal structure.In relation to the global challenge of climate change/global warming, I conclude that traditional media, public service media in particular, together with social media channels play an important role in the process of increasing knowledge and awareness among consumers, politicians and other stakeholders in society. However, in current media development, media companies are rapidly becoming more commercialized and more focused on entertainment instead of on producing serious journalism concerned with social, political and cultural matters.To conclude, I believe that it is possible to create a sustainable media system, but it will require some conscious effort of people working in the media industry, of consumers, and ultimately at the level of regulatory authorities.
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| 3. |
- Zare, Aman, 1987-
(författare)
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Regulation of gene expression in fruit flies : how does it start, and will it be remembered?
- 2018
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- One of the most distinctive features of eukaryotic chromosomes is the bundling of DNA together with functionally associated RNA and proteins in chromatin. This allows huge amounts of DNA to be packed inside the very tiny space of the nucleus, and alterations in the structure of chromatin enable access to the DNA for transcription (“reading” genes by production of RNA copies). Much of the current knowledge of chromatin structure and regulation comes from studies of Drosophila melanogaster. When the chromatin structure is open the transcription of a gene can start after recruitment of the necessary factors. The main enzyme for gene transcription is Polymerase II (Pol II). For successful gene transcription, Pol II must not only be recruited to the gene’s promoter, but also escape from a pausing state which occurs soon after transcription initiation. CBP/P300 is one of the co-activators involved in transcriptional activation. In the studies this thesis is based upon, my colleagues and I (hereafter we) discovered a new function for CBP in transcription activation. Using high throughput sequencing techniques, we found that CBP directly stimulates recruitment of Pol II to promoters, and facilitates its release from the paused state, enabling progression to the elongation stage of transcription.For cells to remember their identity following division during development, the transcriptional state of genes must be transmitted. Intensively studied players involved in this memory are the Polycomb group (PcG) proteins, responsible for maintaining the repressed state of important developmental genes. The core members are Polycomb repressive complex 1 and 2 (PRC1 and PRC2), which are recruited in flies through poorly known mechanisms to target genes by so-called Polycomb response elements (PREs). Using Drosophila mutant cell lines, we showed that (in contrast to previous models) some PREs can recruit PRC1 even when PRC2 is absent. We also observed that at many PREs, PRC1 is needed for recruitment of PRC2 and concluded that targeting PRC complexes to PREs is a much more flexible and variable process than previously thought.Some phenotypic effects of environmental changes can be transferred to subsequent generations. Previous efforts to identify the mechanisms involved have focused on material (mainly, but not only, DNA) transferred through germ cells. However, organisms’ microbiomes are also transferred to the next generation. Thus, to investigate possible contributions of microbiomes to such transfer, we used fruit flies as the microbiomes they inherit can be easily controlled. We altered some parents’ environmental conditions by lowering the temperature, then grew offspring that received microbiomes from cold-treated and control parents in control conditions and compared their transcriptional patterns. Our results suggest that most of the crosstalk between the microbiome and the fly happens in the gut, and that further investigation of this previously unsuspected mode of inheritance is warranted.
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