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- Boström, Lena, 1960-, et al.
(författare)
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Student conceptions of motivation to study revealed through phenomenography: Differences and similarities among primary school students
- 2023
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Ingår i: Social Sciences & Humanities Open. - 2590-2911. ; 8:1, s. 100505-100505
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Tidskriftsartikel (refereegranskat)abstract
- This study examined a group of primary Swedish students' conceptions of their own motivation for learning. Altogether, 68 students in Grades 3, 6, and 8 participated in the study, in which similarities and differences among students in the three grades were considered. Theoretical and methodological aspects were guided by the phenomenographical approach. For most students, positive and negative influences on motivation emerged in seven distinct categories: feelings, teachers, teaching, subjects, learning environment, classmates, and well-being. The apparent importance of good teachers, structured and varied lessons, practical aesthetic subjects and more group-rooms was similar across the three different grades. Differences that emerged were students' reduced joy in learning, decreased interest in mathematics, higher levels of stress and pressure, more worry and anxiety, higher degree of preparation for the future, and a greater need for individualisation for the older students. The study's results confirm previous research but also provide new knowledge about variations across the grades and more specific factors that promote or inhibit students' motivation to study.
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- Hazer Rosberg, Derya Burcu, et al.
(författare)
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Gold and Cobalt Oxide Nanoparticles Modified Poly-Propylene Poly-Ethylene Glycol Membranes in Poly (epsilon-Caprolactone) Conduits Enhance Nerve Regeneration in the Sciatic Nerve of Healthy Rats
- 2021
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Ingår i: International Journal of Molecular Sciences. - : MDPI. - 1661-6596 .- 1422-0067. ; 22:13
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Tidskriftsartikel (refereegranskat)abstract
- Reconstruction of nerve defects is a clinical challenge. Autologous nerve grafts as the gold standard treatment may result in an incomplete restoration of extremity function. Biosynthetic nerve conduits are studied widely, but still have limitations. Here, we reconstructed a 10 mm sciatic nerve defect in healthy rats and analyzed nerve regeneration in poly (epsilon-caprolactone) (PCL) conduits longitudinally divided by gold (Au) and gold-cobalt oxide (AuCoO) nanoparticles embedded in poly-propylene poly-ethylene glycol (PPEG) membranes (AuPPEG or AuCoOPPEG) and compared it with unmodified PPEG-membrane and hollow PCL conduits. After 21 days, we detected significantly better axonal outgrowth, together with higher numbers of activated Schwann cells (ATF3-labelled) and higher HSP27 expression, in reconstructed sciatic nerve and in corresponding dorsal root ganglia (DRG) in the AuPPEG and AuCoOPPEG groups; whereas the number of apoptotic Schwann cells (cleaved caspase 3-labelled) was significantly lower. Furthermore, numbers of activated and apoptotic Schwann cells in the regenerative matrix correlated with axonal outgrowth, whereas HSP27 expression in the regenerative matrix and in DRGs did not show any correlation with axonal outgrowth. We conclude that gold and cobalt-oxide nanoparticle modified membranes in conduits improve axonal outgrowth and increase the regenerative performance of conduits after nerve reconstruction.
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- Hazer Rosberg, Derya Burcu, et al.
(författare)
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Gold and cobalt oxide nanoparticles modified poly‐propylene poly‐ethylene glycol membranes in poly (E‐caprolactone) conduits enhance nerve regeneration in the sciatic nerve of healthy rats
- 2021
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Ingår i: International Journal of Molecular Sciences. - : MDPI AG. - 1661-6596 .- 1422-0067. ; 22:13
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Tidskriftsartikel (refereegranskat)abstract
- Reconstruction of nerve defects is a clinical challenge. Autologous nerve grafts as the gold standard treatment may result in an incomplete restoration of extremity function. Biosynthetic nerve conduits are studied widely, but still have limitations. Here, we reconstructed a 10 mm sciatic nerve defect in healthy rats and analyzed nerve regeneration in poly (ɛ‐caprolactone) (PCL) conduits longitudinally divided by gold (Au) and gold‐cobalt oxide (AuCoO) nanoparticles embedded in poly‐propylene poly‐ethylene glycol (PPEG) membranes (AuPPEG or AuCoOPPEG) and compared it with unmodified PPEG‐membrane and hollow PCL conduits. After 21 days, we detected significantly better axonal outgrowth, together with higher numbers of activated Schwann cells (ATF3‐labelled) and higher HSP27 expression, in reconstructed sciatic nerve and in corresponding dorsal root ganglia (DRG) in the AuPPEG and AuCoOPPEG groups; whereas the number of apoptotic Schwann cells (cleaved caspase 3‐labelled) was significantly lower. Furthermore, numbers of activated and apoptotic Schwann cells in the regenerative matrix correlated with axonal outgrowth, whereas HSP27 expression in the regenerative matrix and in DRGs did not show any correlation with axonal outgrowth. We conclude that gold and cobalt‐oxide nanoparticle modified membranes in conduits improve axonal outgrowth and increase the regenerative performance of conduits after nerve reconstruction.
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- Karlsson Potter, Hanna, et al.
(författare)
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Precision nitrogen application – potential to lower the climate impact of crop production
- 2022
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The agriculture sector is a significant contributor to global greenhouse gas emissions, especially methane (CH4) and nitrous oxides (N2O). Nitrous oxide emissions originate primarily from nitrogen fertiliser production and use. A nitrogen fertilisation rate close to crop demand is desirable for several reasons, e.g. it limits fertiliser use per unit of crop produced and reduces the risk of N2O emissions and nitrogen leaching.This study estimated the impact of two different measures for more accurate nitrogen fertilisation, field-specific nitrogen fertilisation (accounting for between-field variation) and variable-rate nitrogen application (accounting for within-field variation), compared with a uniform fertilisation application. Effects on nitrogen leaching, N2O emissions, grain yield and nitrogen balance were analysed. Calculations of leaching and N2O emissions were based on different examples of within- and between-field variation on two soil types, represented by two experimental fields in south-west Sweden from which measured data on grain yield and N2O emissions were obtained. Climate impact in a life cycle perspective, including fertiliser production and use, was calculated. The results for N2O emissions were compared with the results of simulations using the IPCC model for N2O emissions and a nitrogen balance-based model.According to the results, the climate impact from field N2O emissions was reduced by around 5% when using field-specific nitrogen fertilisation. An additional reduction of 1-10% (depending on in-field variations in nitrogen demand) was achieved when using variable-rate nitrogen application. The amount of fertiliser used was very important for the overall climate impact of crop production, indicating that measures which increase nitrogen use efficiency and keep nitrogen fertiliser doses below the optimum rate are preferable in a climate impact perspective. The commonly used IPCC model for predicting field N2O emissions failed to predict reductions in N2O from better nitrogen use efficiency. The nitrogen balance-based model performed better in predicting field N2O emissions in relation to what could be expected based on measured N2O emissions, but the estimated reduction was not as high as that predicted from field measurements.
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- Lindblom, Sebastian, et al.
(författare)
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A person-centred care transition support for people with stroke/TIA : A study protocol for effect and process evaluation using a non-randomised controlled design.
- 2024
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Ingår i: PLOS ONE. - 1932-6203. ; 19:3
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: Care transitions following a stroke call for integrated care approaches to reduce death and disability. The proposed research described in this study protocol aims to evaluate the effectiveness of a person-centred multicomponent care transition support and the process in terms of contextual moderators, implementation aspects and mechanisms of impact.METHODS: A non-randomized controlled trial design will be used. The intervention includes person-centred dialogue intended to permeate all patient-provider communication, various pedagogical modes of information, a person-centred care and rehabilitation plan, and a bridging e-meeting to prepare patients for homecoming. Patients with stroke or TIA who are to be discharged from the participating hospitals to home and referred to a neurorehabilitation team for continued rehabilitation will be included. Follow-ups will be conducted at one week, 3 months and 12 months. Data will be collected on the primary outcome of perceived quality of the care transition, and on the secondary outcomes of health literacy, medication adherence, and perceived person-centeredness. Data for process evaluation will be collected through semi-structured interviews, focus groups, participatory observations, and the Normalisation Measure Development Questionnaire.DISCUSSION: The study will provide insights on implementation, mechanisms of impact, contextual moderators, and effectiveness of a care transition support, targeting a poorly functioning part of the care trajectory for people with stroke and TIA.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT05646589.
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- Lindblom, Sebastian, et al.
(författare)
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The Use of Teach Back at Hospital Discharge to Support Self-Management of Prescribed Medication for Secondary Prevention after Stroke-Findings from A Feasibility Study
- 2023
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Ingår i: Healthcare. - : MDPI AG. - 2227-9032. ; 11:3
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Tidskriftsartikel (refereegranskat)abstract
- The study aimed to investigate whether a structured discharge letter and the use of the person-centred communication method Teach Back for sharing information at hospital discharge could support perceived understanding and knowledge of and adherence to prescribed medication for secondary prevention after stroke. Data from a feasibility study of a codesigned care transition support for people with stroke was used. Patients who at discharge received both a structured discharge letter and participated in the person-centred communication method Teach Back (n = 17) were compared with patients receiving standard discharge procedures (n = 21). Questionnaires were used to compare the groups regarding perceived understanding of information about medical treatment, knowledge of information about medical treatment and medication adherence at 1 week and 3 months. There was a statistically significant difference in perceived understanding of information about medical treatment (p > 0.01) between the groups in favour of those who participated in Teach Back at the discharge encounter. No differences between groups were found regarding understanding health information about medical treatment and medication adherence. The results indicate that the use of Teach Back at the discharge encounter positively impacts perceived understanding of information about medical treatment in people with stroke. However, considering the nonrandomised study design and the small sample size, a large-scale trial is needed.
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