| 1. |
- Chen, J., et al.
(författare)
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Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells
- 1994
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Ingår i: Immunity. - : Cell Press. - 1074-7613 .- 1097-4180. ; 1:1, s. 65-72
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Tidskriftsartikel (refereegranskat)abstract
- To determine the potential roles of c-jun in lymphocyte development, we generated somatic chimeric mice by injecting homozygous c-jun mutant embryonic stem (ES) cells into blastocysts from recombination activating gene-2 (RAG-2)-deficient mice. Chimeric mice had poor restoration of thymocytes, but contained substantial numbers of mature T and B lymphocytes in the periphery. Stimulation of c-jun-/- B cells resulted in normal levels of proliferation and immunoglobulin secretion. Likewise, stimulation of c-jun-/- T cells resulted in essentially normal levels of IL-2R alpha expression, IL-2 secretion, and proliferation. We further showed that the relatively normal activation responses of the c-jun-/- T cells probably results from the fact that other members of the Jun family contribute to the bulk of the activator protein-1 (AP-1) complexes in normal T cells and, as a result, AP-1 complexes are found at relatively normal levels in c-jun-/- T cells.
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| 2. |
- Da Via, C, et al.
(författare)
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Lightwave Analogue Links For LHC Detector Front-ends
- 1994
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Ingår i: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - : Elsevier BV. - 0167-5087 .- 0168-9002. ; 344:1, s. 199-211
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Tidskriftsartikel (refereegranskat)abstract
- The requirements on optical links for transferring analog and digital signals from the detector front-ends to the readout electronics at future high-luminosity colliders are reviewed. The advantages of external modulation techniques are discussed. An outline is given of the the R&D programme recently started at CERN by a collaboration involving high-energy physics institutes, optoelectronics research laboratories and industry, in order to develop electro-optic intensity modulator arrays, particularly for analogue applications, and to investigate the feasibility of volume production. The design of multichannel demonstrators in lithium niobate and III-V semiconductor technology is described. Preliminary results of the performance measurements are presented.
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| 3. |
- Hunter, William W, et al.
(författare)
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Comparative performance study of longitudinal roadside barriers and end treatments
- 1994
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Ingår i: Proceedings of Strategic Highway Research Program (SHRP) and traffic safety on two continents. Conference in Hague, Netherlands, September 22-24, 1993. - Linköping : Statens väg- och transportforskningsinstitut. ; , s. 119-142
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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