| 1. |
- Huttner, Hagen B, et al.
(författare)
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The age and genomic integrity of neurons after cortical stroke in humans
- 2014
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Ingår i: Nature Neuroscience. - : Springer Science and Business Media LLC. - 1097-6256 .- 1546-1726. ; 17:6, s. 801-803
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Tidskriftsartikel (refereegranskat)abstract
- It has been unclear whether ischemic stroke induces neurogenesis or neuronal DNA rearrangements in the human neocortex. Using immunohistochemistry; transcriptome, genome and ploidy analyses; and determination of nuclear bomb test-derived (14)C concentration in neuronal DNA, we found neither to be the case. A large proportion of cortical neurons displayed DNA fragmentation and DNA repair a short time after stroke, whereas neurons at chronic stages after stroke showed DNA integrity, demonstrating the relevance of an intact genome for survival.
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| 2. |
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| 3. |
- Popovski, Petar, et al.
(författare)
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EU FP7 INFSO-ICT-317669 METIS, D2.1, Requirement analysis and design approaches for 5G air interface
- 2013
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This document describes the problem space for the METIS research conducted in the radio link context. Firstly, a requirement analysis for the air interface design is conducted based on the test case descriptions presented in METIS deliverable D1.1. It follows an introduction of the research topics being pursued in the radio link research together with an illustration of how these topics are addressing the derived requirements. Moreover, it is shown which of thoserequirements address the needs of the METIS horizontal topics. To facilitate the achievement of these three objectives, a framework of General Requirements is introduced, which will be used throughout the project to assess and evaluate developed radio link solutions and to allow for measuring against the overall system performance goals.
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| 4. |
- Popovski, Petar, et al.
(författare)
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EU FP7 INFSO-ICT-317669 METIS, D2.2 Novel radio link concepts and state of the art analysis
- 2013
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This document provides a detailed overview of the Radio Link concepts being developed in METIS as well as a detailed analysis of the related state of the art. For each of the research topics identified for the radio link research covering flexible air interface, new waveforms,modulation and coding techniques as well as multiple access, medium access control and enablers for radio resource management, a detailed description of the aspects to be investigated will be given, going beyond the limits imposed by the systems operated today and their planned evolutions. The state of the art analysis, which is conducted for each of the research topics separately, covers current standards, their future evolutions as well as latest academic research. Elaborating on how the approaches followed in the radio link research may advance this state of the art carves a promising track towards innovative solutions addressing the challenges of future wireless communication.
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| 5. |
- Popovski, Petar, et al.
(författare)
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EU FP7 INFSO-ICT-317669 METIS, D2.3 Components of a new air interface - building blocks and performance
- 2014
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This document provides intermediate results of the concepts being developed in the radio link research of METIS. For each of the technology components (TeC) within the technology component clusters (TeCC), covering flexible air interface, new waveforms, modulation and coding techniques as well as multiple access, medium access control and enablers for radio resource management, key findings and conclusions collected so far are summarized in section 2. Continuative descriptions and research outcomes are given in the annex and referred publications.The results presented here will be extended in the further progress of the project, and they will be used in the next phase of the project to develop and refine the overall METIS system concept instantiated by the horizontal topics. The suitability of the single technology components for the overall system design being able to meet the wide range of requirements for 5G will then be evaluated.
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| 6. |
- Ström, Mikael, 1959, et al.
(författare)
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Transformation to Lean Product Development – Approaches at Two Automotive Suppliers
- 2012
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Ingår i: 12th International Design Conference, DESIGN 2012; Dubrovnik; Croatia; 21 May 2012 through 24 May 2012. - 1847-9162. ; DS 70, s. 113-122, s. 113-122
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Konferensbidrag (refereegranskat)abstract
- The transformation to a lean product development system was studied at two automotive suppliers. The study covers the transformation approach, the problems along the way, some early results of the transformation and a comparison between the two firms in this respect. Both strive to change their operations to add more value in their delivery to the OEM (Original Equipment Manufacturer). The results show that the transformations are experienced as positive in both firms. It is demonstrated that this success is due to methods and principles included in the lean product development framework.
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