| 1. |
- Grönlund, Marita Andersson, 1959, et al.
(författare)
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Relationships between ophthalmological and neuropaediatric findings in children adopted from Eastern Europe.
- 2010
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Ingår i: Acta ophthalmologica. - : Wiley. - 1755-3768 .- 1755-375X .- 1395-3907 .- 1600-0420. ; 88:2, s. 227-34
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: This study aimed to evaluate and relate visual function, ocular dimensions and neuropaediatric findings in adoptees from Eastern Europe. METHODS: We studied 72 of 99 children, born during 1990-95 and adopted from Eastern Europe to western Sweden during 1993-97. The children (mean age 7.5 years, range 4.8-10.5 years; 41 boys, 31 girls) were examined after a mean period of 5 years post-adoption by a multidisciplinary team. Correlations between ophthalmological findings and neuropaediatric data were analysed. RESULTS: Bivariate and regression analyses indicate a significant positive correlation between visual acuity (VA) and perceptual organization (p < 0.001), as well as between strabismus and verbal comprehension (p < 0.02). Fetal alcohol syndrome (FAS) was correlated with low VA (p < 0.02), subnormal stereovision (p < 0.009) and small optic discs (p < 0.02). Small head circumference was related to low VA (p < 0.015) and small optic discs (p < 0.03). Furthermore, small optic discs were related to low birthweight (p < 0.005) and preterm birth (p < 0.01). Large optic cups were correlated with poorer perceptual organization (p < 0.02). CONCLUSIONS: In this group of adoptees from Eastern Europe, ophthalmological findings were correlated to neuropaediatric findings, especially those arising from prenatal adverse events resulting in growth deficiency and central nervous system damage. Therefore, it is important and valuable with an ophthalmological examination in children adopted from Eastern Europe.
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| 2. |
- Landgren, Magnus, 1955, et al.
(författare)
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Prenatal alcohol exposure and neurodevelopmental disorders in children adopted from eastern Europe.
- 2010
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Ingår i: Pediatrics. - : American Academy of Pediatrics (AAP). - 1098-4275 .- 0031-4005. ; 125:5
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: The purposes of this investigation were to determine the frequencies of and associations between different neurodevelopmental disorders and to study the potential lasting effects of alcohol on children adopted from eastern Europe. METHODS: In a population-based, prospective, observational, multidisciplinary, cross-sectional, cohort study of 71 children adopted from eastern Europe, children were assessed 5 years after adoption, from pediatric, neuropsychological, and ophthalmologic perspectives. RESULTS: Fetal alcohol spectrum disorders, that is, fetal alcohol syndrome (FAS), partial FAS, and alcohol-related neurodevelopmental disorders, were identified for 52% of children; FAS was found for 30%, partial FAS for 14%, and alcohol-related neurodevelopmental disorders for 9%. Alcohol-related birth defects were found for 11% of children, all of whom also were diagnosed as having FAS. Mental retardation or significant cognitive impairment was found for 23% of children, autism for 9%, attention-deficit/hyperactivity disorder for 51%, and developmental coordination disorder for 34%. CONCLUSIONS: Fetal alcohol spectrum disorders and neurodevelopmental disorders were common in this long-term follow-up study of children adopted from orphanages in eastern Europe. Maternal alcohol consumption during pregnancy has long-lasting adverse effects, causing structural, behavioral, and cognitive damage despite a radically improved environment.
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| 3. |
- Rangmar, Jenny, et al.
(författare)
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A retrospective register study on psychosocial functioning in adults with fetal alcohol syndrome.
- 2010
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Ingår i: First European Conference on Fetal Alcohol Syndrome, Kerkrade, the Netherlands.
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Konferensbidrag (refereegranskat)abstract
- Few studies focus on psychosocial functioning in adults with fetal alcohol syndrome (FAS). A previous follow-up study of Swedish children with FAS showed that they had severe problems with social relationships and education, problems that remained throughout childhood. The aim of this register study is to further investigate the past and present social and psychosocial demographics of these children who now are adults (n = 79, mean age 29 [18-49 years], 37 % women and 63 % men). A swedish longitudinal integrated database for health insurance and labour market studies (LISA by Swedish acronym) is used for this purpose. Examples of data that will be utilized from the database LISA are employment, income (e.g. parental leave, unemployment, labour market activity, rehabilitation, early retirement, social assistance), place of residence (county, municipality, parish and property) and highest level of education. Obtained data will be compared to a gender and age matched comparison group, also retreived from the database LISA. Preliminary results show that almost 30 % of the adults with FAS had been subjected to the Swedish enforcement authority and the Social services. Moreover, about 70 % of the individuals had been regularly in contact with the Swedish public employment services. The results indicate that FAS have a major impact on the adult daily life, especially on social and psychosocial demographics.
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