Sökning: WFRF:(Sund Malin 1972 )
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Angiosarcoma in the...
Angiosarcoma in the breast: a population-based cohort from Sweden
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- Olander, Susanne (författare)
- Department of Surgery, Sunderby Hospital, Luleå, Sweden
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- Wennstig, Anna-Karin, 1973- (författare)
- Umeå universitet,Kirurgi,Department of Oncology, Sundsvall Hospital, Sundsvall, Sweden
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- Garmo, Hans (författare)
- Regional Cancer Center, Uppsala University, Uppsala, Sweden
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- Holmberg, Lars (författare)
- Regional Cancer Center, Uppsala University, Uppsala, Sweden; Translational Oncology & Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King’s College London, London, United Kingdom
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- Nilsson, Greger (författare)
- Department of Immunology, Genetics and Pathology, Section of Experimental and Clinical Oncology, Uppsala University, University Hospital, Uppsala, Sweden; Department of Oncology, Gävle Hospital, Gävle, Sweden; Department of Oncology, Visby Hospital, Visby, Sweden
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- Blomqvist, Carl (författare)
- Department of Oncology, Helsinki University Hospital, Helsinki, Finland; Department of Oncology, Örebro University Hospital, Örebro, Sweden
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- Karlsson, Fredrik (författare)
- Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden; Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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- Wickberg, Åsa, 1972- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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- Wärnberg, Fredrik (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
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- Sund, Malin (författare)
- Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Department of Surgery, University of Helsinki, Helsinki University Hospital, Helsinki, Finland
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- Wadsten, Charlotta (författare)
- Umeå universitet,Kirurgi,Department of Surgery, Sundsvall Hospital, Sundsvall, Sweden
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(creator_code:org_t)
- Oxford University Press, 2023
- 2023
- Engelska.
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Ingår i: British Journal of Surgery. - : Oxford University Press. - 0007-1323 .- 1365-2168. ; 110:12, s. 1850-1856
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
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- Background: Breast angiosarcoma is a rare disease mostly observed in breast cancer (BC) patients who have previously received radiotherapy (RT). Little is known about angiosarcoma aetiology, management, and outcome. The study aim was to estimate risk and to characterize breast angiosarcoma in a Swedish population-based cohort. Methods: The Swedish Cancer Registry was searched for breast angiosarcoma between 1992 and 2018 in three Swedish healthcare regions (population 5.5 million). Information on previous BC, RT, management, and outcome were retrieved from medical records. Results: Overall, 49 angiosarcomas located in the breast, chest wall, or axilla were identified, 8 primary and 41 secondary to BC treatment. Median age was 51 and 73 years, respectively. The minimum latency period of secondary angiosarcoma after a BC diagnosis was 4 years (range 4–21 years). The cumulative incidence of angiosarcoma after breast RT increased continuously, reaching 1.4‰ after 20 years. Among 44 women with angiosarcoma treated by surgery, 29 developed subsequent local recurrence. Median recurrence-free survival was 3.4 and 1.8 years for primary and secondary angiosarcoma, respectively. The 5-year overall survival probability for the whole cohort was 50 per cent (95 per cent c.i., 21 per cent–100 per cent) for primary breast angiosarcoma and 35 per cent (95 per cent c.i., 23 per cent–54 per cent) for secondary angiosarcoma. Conclusion: Breast angiosarcoma is a rare disease strongly associated with a history of previous BC RT. Overall survival is poor with high rates of local recurrences and distant metastasis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
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Olander, Susanne
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Wennstig, Anna-K ...
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Garmo, Hans
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Holmberg, Lars
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Nilsson, Greger
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Blomqvist, Carl
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Karlsson, Fredri ...
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Wickberg, Åsa, 1 ...
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Wärnberg, Fredri ...
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Sund, Malin
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Wadsten, Charlot ...
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- MEDICIN OCH HÄLSOVETENSKAP
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och Kirurgi
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MEDICIN OCH HÄLS ...
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- Av lärosätet
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Göteborgs universitet
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Örebro universitet
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Umeå universitet
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Karolinska Institutet