| 1. |
- Amnå, Erik, et al.
(författare)
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En halv miljard av statens pengar riskerar att slösas bort
- 2007
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Ingår i: Göteborgs-Posten. ; 2007-09-13, s. 47-47
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Minskade anslag gör att den årliga undersökningen om våra levnadsförhållanden hotas att halveras. Det kan drabba redan svaga grupper som äldre, invandrare och ensamstående föräldrar.
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| 2. |
- Bergquist, Jonas, et al.
(författare)
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Mass spectrometry of proteins - Uppsala perspectives on past and present : Paper in honor of Prof. Peter Roepstorff's 65th birthday
- 2007
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Ingår i: International Journal of Mass Spectrometry. - : Elsevier BV. - 1387-3806 .- 1873-2798. ; 268:2-3, s. 73-82
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Tidskriftsartikel (refereegranskat)abstract
- The development of biological mass spectrometry has been rapid in the past three to four decades. In particular, the possibility to detect and identify peptides and proteins from biologically and medically relevant samples has revolutionized life sciences. The development has gone from a stage where the detection of insulin in a mass spectrum was a major event to one in which the recording of mass spectra with more than 104 resolved and calibrating peaks in each spectrum is a routine task.In this paper, the evolution of protein mass spectrometry will be discussed from the Uppsala horizon with special emphasis on the unique coupling between ion induced desorption of biomolecules and ion track physics.
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| 3. |
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| 4. |
- Brandén, Henrik, et al.
(författare)
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Preconditioners Based on Fundamental Solutions
- 2005
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- We consider a new preconditioning technique for the iterative solution of linear systems of equations that arise when discretizing partial differential equations. The method is applied to finite difference discretizations, but the ideas apply to other discretizations too.If E is a fundamental solution of a differential operator P, we have E*(Pu)=u. Inspired by this, we choose the preconditioner to be a discretization of an approximative inverse K, given by (Ku)(x)=intOmegaE(x-y)u(y)dy, x∈Omegasubsetmathds{R}d, where Omega is the domain of interest. We present analysis showing that if P is a first order differential operator, KP is bounded, and numerical results show grid independent convergence for first order partial differential equations, using fixed point iterations.For the second order convection-diffusion equation convergence is no longer grid independent when using fixed point iterations, a result that is consistent with our theory. However, if the grid is chosen to give a fixed number of grid points within boundary layers, the number of iterations is independent of the physical viscosity parameter. Also, if GMRES is used together with the proposed preconditioner, the numbers of iterations decrease as the grid is refined, also for fixed viscosity.
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| 5. |
- Cato, Ingemar, et al.
(författare)
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DIOXINS AND OTHER POPS IN THE BALTIC SEA – TRENDS AND CURRENT
- 2009
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Ingår i: 29th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2009) in Bejing, China, August 25-30, 2009.
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Konferensbidrag (refereegranskat)abstract
- This paper summarizes a project that was initiated by the Swedish Environmental Protection Agency (EPA) in 2006. It involved several field studies and fate model calculations with the aim to better understand the present contamination situation of dioxins and other persistent organic pollutants (POPs) in the Baltic Sea region. Atmospheric inputs were found to be the dominant external source for all of the selected POPs (dioxins, PCBs and HCB). The model also predicted a significant decline of POP-levels in Baltic surface water if atmospheric concentrations are reduced. This issue is highly prioritized by the Swedish EPA since TEQ-levels of fatty fish exceed maximum residue limits set by the EU. Dioxin source regions were identified by air measurements and analysis of air mass origin. It was found that air that had passed over the European continent contained the highest concentrations, and the congener composition indicated that several major sources types may exist. This research has high relevance for the Swedish EPA, and continued efforts for resolving the dioxin issue of the Baltic Sea will follow.
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| 6. |
- Cornelissen, Gerard, et al.
(författare)
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Freely Dissolved Concentrations and Sediment-Water Activity Ratios of PCDD/Fs and PCBs in the Open Baltic Sea
- 2008
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Ingår i: Environmental Science and Technology. - : American Chemical Society (ACS). - 0013-936X .- 1520-5851. ; 42:23, s. 8733-8739
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Tidskriftsartikel (refereegranskat)abstract
- Aqueous concentrations of polychlorinated dibenzo-p-dioxins and -furans (PCDD/Fs) as well as polychlorinated biphenyls (PCBs) in the open sea have heretofore been measured by filtering. and extracting large amounts of water. Measurement of freely dissolved concentrations with this technique is difficult because of corrections for sorption to dissolved organic matter. In this study we use a novel, more economic technique using equilibrium passive samplers consisting of 17-mu m thin polyoxymethylene (POM-17), capable of measuring freely dissolved aqueous concentrations (C-W) in pristine (i.e., background) locations. POM-17 was employed in an extensive field campaign at five stations in the open Baltic sea to obtain C-W at two depths (1 m above the seafloor and 25 m below the surface). Median C-W in the overlying water was 2.3 pg toxic equivalents (TEQ)/m(3) PCDD/Fs and 15 pg/L sum 7-PCB, with generally less than a factor two variation among sites and depths. Also freely dissolved concentrations of native compounds in the surface sediment porewater (C-PW) were determined in laboratory batch experiments. The data were used to derive sediment-water activity ratios, which indicate the diffusive flux direction. It was found that the PCDD/Fs and PCBs were in close equilibrium between the sediment porewater and the overlying water. Comparison of C-PW with total sediment concentrations indicated that more than 90% of the compounds were sorbed to sedimentary black carbon.
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| 7. |
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| 8. |
- Holmgren, Sverker, et al.
(författare)
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Can one hear the composition of a drum?
- 2006
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Ingår i: Mediterranean Journal of Mathematics. - : Springer Science and Business Media LLC. - 1660-5446 .- 1660-5454. ; 3, s. 227-249
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Tidskriftsartikel (refereegranskat)
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| 9. |
- Sandström, Per, 1965-, et al.
(författare)
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Serum amino acid profile in patients with acute pancreatitis
- 2008
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Ingår i: Amino Acids. - : Springer Science and Business Media LLC. - 0939-4451 .- 1438-2199. ; 35:1, s. 225-231
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Tidskriftsartikel (refereegranskat)abstract
- Patients in the early phase of acute pancreatitis (AP) have reduced serum levels of arginine and citrulline. This may be of patho-biological importance, since arginine is the substrate for nitric oxide, which in turn is involved in normal pancreatic physiology and in the inflammatory process. Serum amino acid spectrum was measured daily for five days and after recovery six weeks later in 19 patients admitted to the hospital for acute pancreatitis. These patients had abnormal levels of most amino acids including arginine, citrulline, glutamine and glutamate. Phenylalanine and glutamate were increased, while arginine, citrulline, ornithine and glutamine were decreased compared to levels after recovery. NO2/NO3 concentration in the urine, but not serum arginase activity, was significantly increased day 1 compared to day 5 after admission. Acute pancreatitis causes a disturbance of the serum amino acid spectrum, with possible implications for the inflammatory process and organ function both in the pancreas and the gut. Supplementation of selected amino acids could possibly be of value in this severe condition. © 2007 Springer-Verlag.
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