| 1. |
- Ling, Charlotte, et al.
(författare)
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Identification of Functional Prolactin (PRL) Receptor Gene Expression: PRL Inhibits Lipoprotein Lipase Activity in Human White Adipose Tissue
- 2003
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Ingår i: The Journal of Clinical Endocrinology & Metabolism. - : The Endocrine Society. - 0013-7227 .- 1945-7197 .- 0021-972X. ; 88:4, s. 1804-1808
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Tidskriftsartikel (refereegranskat)abstract
- During lactation serum levels of prolactin (PRL) are elevated, and the activity of lipoprotein lipase (LPL) is decreased in the adipose tissue and increased in the mammary gland. However, PRL has been suggested to affect the adipose tissue in an indirect fashion during lactation. In the present study, we demonstrated expression of four PRL receptor (PRLR)mRNA isoforms (L, I, S1a, and S1b) in human sc abdominal adipose tissue and breast adipose tissue using RT-PCR/Southern blot analysis. In addition, L-PRLR [relative molecular mass (Mr) 90,000] and I-PRLR (Mr 50,000) protein expression was detected in human sc abdominal adipose tissue and breast adipose tissue using immunoblot analysis. Two additional protein bands with the molecular weight Mr 40–35,000 were also detected. The direct effect of PRL on the regulation of LPL activity in human abdominal adipose tissue cultured in vitro was investigated. PRL (500 ng/ml) reduced the LPL activity in human adipose tissue to 31 +/- 7.7%, compared with control.GH (100 ng/ml) also reduced the LPL activity, to 45 +/- 8.6%, compared with control. In agreement with previous studies, cortisol increased the LPL activity and GH inhibited cortisolinduced LPL activity. Furthermore, we found that PRL also inhibited the cortisol-induced LPL activity. Taken together, these results demonstrate a direct effect of PRL, via functional PRLRs, in reducing the LPL activity in human adipose tissue, and these results suggest that LPL might also be regulated in this fashion during lactation.
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| 2. |
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| 3. |
- Andersson, Maria
(författare)
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Arbetslöshet och arbetsfrihet : Moral, makt och motstånd
- 2003
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Unemployment is constructed as a problem by institutions and individuals, at a structural as well as individual level. In the "black discourse" of unemployment, power is produced by talking and naming, by symbolic images, by dichotomisation and hierarchisation of categories based on the fundamental dichotomy of nature/reason, but also by feelings, actions and bodies. The well-being of the unemployed is constantly threatened by this discourse, yet they nevertheless reproduce it when necessary. But there is resistance to all this. First, there is a resistance against politicians and former employees in particular and elites in general. Then there is a reflexive resistance, characterised by a critique and de-legitimation of the myths of unemployment and thereby the modern work ethic. This depreciation of values and a relativistic standpoint is seen here as a sign of a representational crisis. In the practising of a life free from work, I also see a kind of resistance. The women seem to need what I call an "existential space", sometimes fulfilled in unemployment. The men living happily without work seem to need an ideological legitimation of this, rejecting the materialistic lifestyle in the contemporary western world. Finally, I see a kind of "practised resistance" (often unintended) in alternative outcome, such as the mutual help in a "moral economy", small-scale cultivating, fishing and hunting and economic strategies. Since the discourse of unemployment is motivated by the relation between the modern institutions of wage labour and capitalism, the activities based on other relations, such as reciprocity and non-consumption in this case, can be defined as a kind of resistance. It is a resistance readable in the effect, not the intention, of it.
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| 4. |
- Beckman, Viveca, et al.
(författare)
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Att socialiseras in i vuxenlivet
- 2004
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Ingår i: Holmqvist, Mona (red.). En främmande värld. - Lund : Studentlitteratur. ; , s. 170-188
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Eneroth, Åsa, et al.
(författare)
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Contamination of pasteurised milk by Bacillus cereus in the filling machine
- 2001
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Ingår i: Journal of Dairy Research. - 0022-0299. ; 68:2, s. 189-196
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Tidskriftsartikel (refereegranskat)abstract
- The contamination of pasteurized milk by Bacillus cereus during the ®lling process was studied in two dairy plants. Samples of pasteurized milk were taken at four different sites along the production line. The samples were stored at 7 °C for 7 d, or at 10 °C for 5 d, before plate counting and random selection of B. cereus isolates. Isolates of B. cereus were typed by the polymerase chain reaction (PCR)-based method randomly ampli®ed polymorphic DNA (RAPD). Samples taken at three different sites between the pasteurizer and the ®lling machine were all holding similar low concentrations of B. cereus, while an increase of the B. cereus count was seen in the consumer packages. More B. cereus of different RAPD types was growing in the consumer packages than in samples taken just before the ®lling machine. Several RAPD types found in the consumer packages were not detected in the samples taken just before the ®lling machine.
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| 6. |
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| 7. |
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| 8. |
- Lagerkvist, Birgitta Json, et al.
(författare)
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Pulmonary epithelial integrity in children: relationship to ambient ozone exposure and swimming pool attendance.
- 2004
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Ingår i: Environmental health perspectives. - 0091-6765. ; 112:17, s. 1768-71
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Tidskriftsartikel (refereegranskat)abstract
- Airway irritants such as ozone are known to impair lung function and induce airway inflammation. Clara cell protein (CC16) is a small anti-inflammatory protein secreted by the nonciliated bronchiolar Clara cells. CC16 in serum has been proposed as a noninvasive and sensitive marker of lung epithelial injury. In this study, we used lung function and serum CC16 concentration to examine the pulmonary responses to ambient O3 exposure and swimming pool attendance. The measurements were made on 57 children 10-11 years of age before and after outdoor exercise for 2 hr. Individual O3 exposure was estimated as the total exposure dose between 0700 hr until the second blood sample was obtained (mean O3 concentration/m3 times symbol hours). The maximal 1-hr value was 118 microg/m3 (59 ppb), and the individual exposure dose ranged between 352 and 914 microg/m3hr. These O3 levels did not cause any significant changes in mean serum CC16 concentrations before or after outdoor exercise, nor was any decrease in lung function detected. However, children who regularly visited chlorinated indoor swimming pools had significantly lower CC16 levels in serum than did nonswimming children both before and after exercise (respectively, 57 +/- 2.4 and 53 +/- 1.7 microg/L vs. 8.2 +/- 2.8 and 8.0 +/- 2.6 microg/L; p < 0.002). These results indicate that repeated exposure to chlorination by-products in the air of indoor swimming pools has adverse effects on the Clara cell function in children. A possible relation between such damage to Clara cells and pulmonary morbidity (e.g., asthma) should be further investigated.
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| 9. |
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| 10. |
- Silvén, Eva, 1949-
(författare)
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Bekänna färg : Modernitet, maskulinitet, professionalitet
- 2004
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Paint and painting are obvious components of everyday life for those of us who live in contemporary Sweden. In terms of both matter and shade, paint has come to symbolise taste and status as well as having created distinction, defined sex/gender and social position – with the past as a constant sounding board. Paint and painting also have professional and occupational aspects. There are people – usually males – who train to become and earn their living as painters. At the same time, there are many others who are active in the professional production of paint and painting. Furthermore, there is a large amateur sector where “everyone” can paint. Taken together, these form a kind of social field characterised by both conflict and consensus: a field where competence and legitimacy, aesthetics and quality and the right to instruct and assess are questioned. These are the conditions that form the subject of this dissertation. In a wider sense the aim is to illustrate colour, paint and painting as constantly interpreted and reinterpreted material, cultural and social phenomena, with the power to shape and alter people’s circumstances and relationships. For this purpose I have come to use a variety of sources from the 20th century, such as narratives, photographs, advertisements, historical accounts and artefacts. In a more restricted sense, and against this background, the aim is to analyse the house painters’ work on a large-scale renovation project, through comprehensive fieldwork. Being modern is not so much about managing the age in which we live and the future, as managing the past. Although the social field of painting generates a series of contradictory norms and ideals, the historical heritage represents a mutual frame of reference, irrespective of whether the tendency is to integrate, separate or reconstruct the past – different systems or knowledge with normative claims, discourses. In these processes the paint, in terms of both matter and shade, is regarded as a floating signifier, something that people struggle to define, over a period of time. In order to study how this process works, I have made use of three analytical concepts: modernity, masculinity and professionalism. These concepts both act through and are created by what I have chosen to call material, bodily and aesthetic practices. With the help of a relational power-perspective, I have built the main chapters, focused on the renovation project, around a number of such phenomena: rhythm and movement, the material, the performative and the aesthetic, the body, sex/gender, class and pro-fessionalism, as well as the social implications of space and place. It is here that the actors in the field come into contact with each other: modern house painters, decorative painters, antiquarians, architects, paint producers, and others. It is here that insistence on the preferential right of interpretation is at risk and where an image of “the other” is conjured up.The dissertation is concluded by the heading, In the Draught of Discourse, where the painting trade and the work itself is described as transparent and available to “everybody”. Through discourse analysis and fieldwork, it has been possible to illustrate how conditions and possibilities are not only created in the painting field itself, but also in many other sectors of society. To show your colours is to reveal sex/gender, class and nationality, to define continuity and change, the traditional and the modern, to separate amateurs and professionals, the preparative groundwork and the final result. And it is here, at the ambiguous interface that the finished surface represents, that the dissertation is concluded.
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