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- Davidsson, Johan, 1967, et al.
(författare)
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BioRID - A New Biofidelic Rear Impact Dummy
- 1998
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Ingår i: Proceeding of the 1998 International IRCOBI Conference on the Biomechanics of Impact. ; , s. 377-390
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Konferensbidrag (refereegranskat)
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| 4. |
- Davidsson, Johan, 1967, et al.
(författare)
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BioRID P3 – Design and Performance Compared to Hybrid III and Volunteers in Rear Impacts at ΔV=7 km/h
- 1999
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Ingår i: Proceeding of the 43rd STAPP Car Crash Conference, San Diego, USA. ; :SAE paper no. 99SC16, s. 253-265
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Konferensbidrag (refereegranskat)abstract
- Several investigators have noted limitations of the most commonly used dummy in rear impact testing, the Hybrid III. A dummy for rear impact testing, the BioRID I, has previously been presented. It was a step towards an effective tool for seat performance testing, but it was concluded that its neck extension and T1 upward motion were too small and that its user-friendliness could be improved.A new BioRID prototype has been developed. It has new neck muscle substitutes with damping and elastic elements that are independent of each other and fitted inside the torso. The new neck muscle substitutes extend to T3 and thus also load the upper thoracic spine. The new dummy has a softer thoracic spine and a torso made of softer rubber than was used for the original dummy. The BioRID prototype's performance was compared to that of volunteers, the BioRID I and Hybrid III in rear impacts at V=7 km/h. The kinematics response of the new BioRID prototype appears to be more human-like than that of the BioRID I and Hybrid III. The dummy also provides repeatable test results and is more user-friendly than the BioRID I.
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- Davidsson, Johan, 1967, et al.
(författare)
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Human Volunteer Kinematics in Rear-End Sled Collisions
- 1998
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Ingår i: Proceeding of the 1998 International IRCOBI Conference on the Biomechanics of Impact. ; , s. 289-301
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Konferensbidrag (refereegranskat)abstract
- A number of current projects are developing new crash test dummies for rear-end impact testing. The validation of such a dummy design requires human response data from pertinent test situations. The objectives of this study are to quantify human head, neck, chest, pelvis and femur mechanical response in a well defined test seat. Another aim is to see how the response varies with seat design and sled speed change during low-speed rear-end collisions. This data is intended to be used in the validation of the crash test dummy (BioRID I) in rear-end impact situations, with a focus on low delta V (velocity change) collisions. Thirteen human subjects were exposed to 28 rear-end collision sled impacts with velocity changes close to 5 and 7 krn/h respectively. The results showed vertical motion of the subjects' H-point caused by ramping up along the seat, a forward rotat ion of the subjects' femur and maybe a contraction of the subjects' gluteus muscles. A vertical motion of the subjects' torso and head was also observed. This motion was caused by a combination of ramping up along the seat back and the straightening of the thoracic kyphosis. In the first 100 ms after impact, several subjects flexed their head relative T1. These new data have proven to be useful as validation data for new rear-end impact dummies.
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- Herlitz, Johan, et al.
(författare)
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Similar risk reduction of death of extended-release metoprolol once daily and immediate release metoprolol twice daily during 5 years after myocardial infarction
- 1999
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Ingår i: Cardiovascular Drugs and Therapy. - : Springer New York LLC. - 0920-3206 .- 1573-7241. ; 13:2, s. 127-135
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Tidskriftsartikel (refereegranskat)abstract
- The pooled results from five placebo-controlled postinfarction studies with metoprolol have shown a significant reduction in total mortality. All five studies used immediate-release metoprolol twice daily. An extended-release formulation of metoprolol for once-daily use has since been developed. The aim of the present study was to compare the two different forms of metoprolol with regard to the risk reduction of death for 5 years postinfarction and to analyze whether treatment with the beta-blocker metoprolol is associated with a reduced mortality after the introduction of modern therapies such as thrombolysis, aspirin, and ACE inhibitors. All patients discharged after an acute myocardial infarction (AMI) from Sahlgrenska University Hospital (SU) during 1986-1987 (n = 740, Period I) and during 1990-1991 (n = 1446, Period II) from both SU and Ostra Hospital, Göteborg, Sweden, were included in the study. During Period I, 56% were prescribed immediate-release metoprolol compared with 61% prescribed extended-release metoprolol during Period II. Immediate-release metoprolol was not available for outpatient use during Period II. In a multivariate analysis, all variables significantly associated with either increased or decreased postinfarction mortality during Periods I and II (univariate analysis of patient characteristics, medical history, complications during the AMI medication at discharge) studied were with Cox's proportional hazards model. Treatment with immediate-release metoprolol was significantly associated with reduced mortality over 5 years during Period I (relative risk reduction for total mortality, -34%, P = 0.003; 95% CI for RR, 0.51-0.87), and treatment with extended-release metoprolol was significantly associated with reduced mortality during Period II (-34%, P < 0.0001; 95% CI for RR, 0.53-0.82). Thrombolysis and the use of aspirin and ACE inhibitors were more frequently used during Period II. The results showed that postinfarction treatment with extended-release metoprolol given once daily was associated with a similar risk reduction of death over 5 years as immediate-release metoprolol given twice daily. The data, furthermore, indicate that the beta-blocker metoprolol is associated with a reduced risk of death after the introduction of modern therapy such as thrombolysis, aspirin, and ACE inhibitors.
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| 8. |
- Kjellgren, Karin I, 1950, et al.
(författare)
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Antihypertensive medication in clinical encounters.
- 1998
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Ingår i: International journal of cardiology. - 0167-5273. ; 64:2, s. 161-9
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Tidskriftsartikel (refereegranskat)abstract
- In managing hypertension, patient participation and understanding of the nature and significance of treatment are decisive. We analysed the communication between patient and physician with respect to antihypertensive medication at a follow-up appointment, and assessed patients' knowledge of their medication. The empirical data consist of audio-recordings from 51 hypertensive patients' follow-up appointment with their physicians. Thirty-three of these patients were interviewed in depth immediately after the appointment. The study was performed in primary health care centres and at a specialist clinic for hypertension. When discussing medications, patients mainly talked about experiences of being on medication, whereas physicians generally focused on the pharmacological effect and dosage of the drug. Physicians routinely asked about compliance with drug regimen, but seldom in any depth. Little effort was invested into discussing the effect and goal of therapy. The main finding was that patients had a very fragmentary understanding of the functional nature of their antihypertensive medication. This is unsatisfactory both from the point of view of treatment efficacy and also when considering the legal requirements of involving the patient in the decision making. The follow-up appointments studied gave few possibilities for the patient to learn about their antihypertensive medication.
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| 9. |
- Kjellgren, Karin I, 1950, et al.
(författare)
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Hypertensive patients' knowledge of high blood pressure.
- 1997
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Ingår i: Scandinavian journal of primary health care. - 0281-3432. ; 15:4, s. 188-92
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To investigate hypertensive patients' understanding of the circulatory system, in particular high blood pressure. DESIGN: Semi-structured audio-taped interviews of patients immediately after a regular follow-up appointment with their physician. SETTING: A primary health care centre and a specialist clinic (hypertension unit) in southern Sweden. PATIENTS: 33 hypertensive patients, consecutively selected. MAIN OUTCOME MEASURE: Focus was set on the exploration of patients' understanding/knowledge. RESULTS: In spite of a long history of hypertensive care, on average ten years, patients had a less than satisfactory understanding of their condition. Most patients knew their blood pressure values, but very few were able to give an account of what high blood pressure implies in functional terms. Knowledge of high blood pressure seems mainly to be derived from sources other than the health care system, in particular from the mass media. Knowledge of the risks associated with hypertension was quite good, as was the insight into how these risks could be managed. CONCLUSION: An assessment of patient knowledge of high blood pressure ought to be a starting point for educational strategies that aim to deepen patients' understanding of their state of health.
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| 10. |
- Linder, Astrid, et al.
(författare)
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The New Neck Design for the Rear-End Impact Dummy, BioRID I
- 1998
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Ingår i: Annual Proceedings. - : Association for the Advancement of Automotive Medicine. ; , s. 172-192
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- A new mechanical neck was developed for a new dummy possessing a complete articulated spine, for low speed rear-end collisions. The new neck consists of seven cervical elements connected by hinge joints. The neck stiffness properties were created by rubber blocks between each pair of vertebrae in combination with simulated muscle elements between the head and T1. The neck was validated against volunteer tests (Δv of 7 km/h) results. Both displacement and acceleration of the head relative to the upper torso for both duration and peak values, were in agreement with the volunteer data.
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