| 1. |
- Billig, Håkan, 1955, et al.
(författare)
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Follicular development and apoptosis.
- 2002
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Ingår i: Ernst Schering Research Foundation workshop. - 0947-6075. ; :41, s. 23-41
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Holdfeldt, Peter, 1976, et al.
(författare)
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EnViDiA: an educational environment for visualization of distributed algorithms in virtual environments
- 2002
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Ingår i: ITiCSE '02 Proceedings of the 7th annual conference on Innovation and technology in computer science education. - New York, NY, USA : ACM. - 1581134991 ; , s. 226-
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- EnViDiA is an extensible environment that visualizes the execution of distributed algorithms by using the visualization enhancements offered by Virtual Reality technology. It addresses to represent the complex flow of information tied with the execution of a distributed algorithm in a way that also novices can easily develop a first understanding of the algorithm behavior. In difference to already existing tools it represents the communication structure in a 3D-model in which users are immersed. This way a natural interaction based on real world behavior is possible.The algorithm must work correctly using any arbitrary inter¿connection of processes represented by a communication graph. In contrast to ordinary 2D-worlds, complex non-planar graph models can be nicely represented in 3D with the perspective adapting to the movements of the user. Further, the orientation in the 3D-world is facilitated providing spatial sound. It assists the user becoming aware of the important system events.Students working within such an environment are more active since they walk or fly through the distributed system world in a game like scenario. Unlike the textbook approach students perceive a whole system execution instead of a series of snapshots for which students may experience difficulties in connecting them. The given experience is intended to help the students to follow better the formal descriptions and analysis of such algorithms.Undergraduate students have developed EnViDiA as part of the LYDIAN [2] project. The animation framework was designed for the Chalmers VR-Cube [1], an immersive VR environment and it is based on the problems the students experienced themselves when studying distributed algorithms for the first time.Although EnViDiA is intended to be used in an immersive VR environment, it is also possible to use EnViDiA in a simpler version on ordinary desktop computers supporting 3D-graphics (c.f. Figure 1). At its current state EnViDiA supports three distributed algorithms namely simple broadcast, broadcast with acknowledgement and resource allocation based on the algorithm by Ricart and Agrawala. The algorithms are taught in a basic distributed system course at Chalmers University of Technology.The development is about to be continued as part of the LYDIAN [2] project. Besides adding more algorithms and evaluating the tool at its current state, the main focus is on providing features to support multiple user collaboration, which are tested at the distributed concept of self-stabilization.
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| 3. |
- Lundberg, Magnus, et al.
(författare)
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Context aware power optimizations of wireless embedded Internet systems
- 2004
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Ingår i: From the electrometer to the networked instruments. - Piscataway, NJ : IEEE Communications Society. - 078038248X ; , s. 91-95
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Konferensbidrag (refereegranskat)abstract
- A key issue in research around embedded Internet systems (EIS) is to reduce power consumption. We envision EIS devices with lifetimes in the range of months or even years. This calls for developing aggressive power management techniques with a high degree of context awareness. As a first step towards this goal we introduce a design methodology for making context aware power optimizations of EIS. The presented design methodology which is verified by experimental results is a promising first step in prolonging operating time of battery powered wireless EIS.
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| 4. |
- Markström, Emilia, et al.
(författare)
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Survival factors regulating ovarian apoptosis -- dependence on follicle differentiation.
- 2002
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Ingår i: Reproduction (Cambridge, England). - 1470-1626. ; 123:1, s. 23-30
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Tidskriftsartikel (refereegranskat)abstract
- Only a minute fraction of the ovarian follicles present in a fetal ovary will complete the path to ovulation. Most of the follicles will undergo atresia, a hormonally controlled apoptotic process. Apoptosis occurs at each stage of follicular development and there is a marked reduction in the number of follicles present at birth. Stage-dependent mechanisms of follicle survival can be postulated to achieve co-ordinated development, leading to ovulation of a small fraction of follicles. Indeed, hormone and growth factor regulation of follicular atresia is stage-specific. This short review considers the factors that promote survival of ovarian follicles throughout development, including endocrine, locally produced and intracellular mediators, as exemplified mainly by follicular development in rodents. In primordial follicles, oocyte apoptosis is considered to be the cause of subsequent follicle degeneration. In slow-growing preantral follicles, FSH is not a survival factor, but some locally produced growth factors are. Progression to the antral follicle stage is probably the most critical stage of follicle development in vivo, and FSH is a major survival factor at this stage. In addition, insulin-like growth factor I and interleukin 1beta are potent survival factors for cultured rat follicles at the antral stage. Preovulatory follicles express receptors for LH, and both of the gonadotrophins are survival factors at this stage. Relatively little is known about the period between the LH surge and ovulation; however, it has been suggested that at this stage progesterone acts as a survival factor.
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| 5. |
- Persson, Helena, et al.
(författare)
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Allozyme diversity and genetic structure of marginal and central populations of Corylus avellana L. (Betulaceae) in Europe
- 2004
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Ingår i: Plant Systematics and Evolution. - : Springer Science and Business Media LLC. - 1615-6110 .- 0378-2697. ; 244:3-4, s. 157-179
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Tidskriftsartikel (refereegranskat)abstract
- Corylus avellana L. (hazel, Betulaceae) is a long-lived, widespread shrub in Europe, having its northern range margin in Fennoscandia and a postglacial history involving range-expansion from refugial areas in southern Europe. In this study, we tested for a relationship between marginality and low within-population genetic diversity by assessing patterns of variation at 14 putatively neutral allozyme loci (comprising 43 putative alleles) within and between 40 natural populations of C. avellana along a north-south transect in Europe. Geographically marginal populations (central Sweden) showed lower levels of within-population diversity than populations in more central regions, as indicated by significant negative correlations between latitude and the percentage of polymorphic loci (r(S)=-0.47, P < 0.001), the average number of alleles per locus (r(S)=-0.65, P < 0.001), the expected heterozygosity (r(S)=-0.19, P < 0.05), and the proportion of distinguishable genotypes (r(S)=-0.56, P < 0.001). These patterns, combined with the unusually high between-population component of gene diversity (G(ST)=19.7%) and allelic richness (A(ST)=24%) in the marginal region, can be attributed to historical bottlenecks during the species' postglacial range-expansion, but may also reflect a history of genetic drift in the small, isolated populations occupying the marginal region. Information on the spatial distribution of genotypes provide further support for a role of vegetative reproduction (layering) in the structuring of genetic variation within populations.
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| 6. |
- Svensson, Eva Ch, et al.
(författare)
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Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells.
- 2001
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Ingår i: Fertility and sterility. - 0015-0282. ; 76:6, s. 1225-31
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To investigate if progesterone receptor (PR)-mediated effects are involved in regulating the susceptibility to apoptosis in LH receptor-stimulated human luteinizing granulosa cells. DESIGN: Laboratory study. SETTING: Göteborg University and an in vitro fertilization laboratory of a university hospital. PATIENT(S): Women undergoing oocyte retrieval for in vitro fertilization after ovulation induction with gonadotropins. INTERVENTION(S): Luteinizing granulosa cells were isolated from follicular aspirates after oocyte removal. The cells were treated with or without RU 486 (1 microM-100 microM), Org 31710 (1 microM-100 microM), progesterone (1 nM-10 microM), dexamethasone (0.5 microM-100 microM), dihydrotestosterone (1 nM-25 microM), RU 486 (10 microM-100 microM) + dexamethasone (50 microM), and picrotoxin (1 microM-100 microM) and were cultured under serum-free conditions. MAIN OUTCOME MEASURE(S): Measurement of caspase-3 activity; detection of internucleosomal DNA fragmentation using gel electrophoresis and fluorospectrophotometry; progesterone analysis of spent medium. RESULT(S): Addition of the PR antagonists RU 486 or Org 31710 in vitro to human luteinizing granulosa cells caused an increase in caspase-3 activity and a dose-dependent increase in internucleosomal DNA fragmentation. No effect on DNA fragmentation was seen after addition of dexamethasone, dihydrotestosterone, or picrotoxin. CONCLUSION(S): Nuclear PR-mediated effects are involved in regulating the susceptibility to apoptosis in LH receptor-stimulated human luteinizing granulosa cells.
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| 7. |
- Svensson, Linus
(författare)
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Low-power embedded Internet system design
- 2004
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Small mobile wireless sensors are used in many different areas, and they are expected to become even more common in the future as the miniaturisation of electronics continues. The current trend of connecting sensors into networks, or wireless sensor networks, is expected to continue and it has the potential to revolutionise our capability to monitor the physical world. To ensure communication compatibility and interoperability between sensors from different manufacturers within one sensor network, it is necessary to use standardised communication protocols. The most widespread network-independent protocol is IP, and we feel confident that IP will fill an important role in future sensor networks. For a number of reasons, including short development times and low development costs, a significant number of these systems are built using commercial-of-the-shelf (COTS) components. As development times and costs certainly will continue to be an issue which cannot be ignored, we believe that COTS components will be used in many future systems. Another issue is the power consumption: depending on the application area, the requirements on a system’s operational lifetime varies, but with few exceptions, low power consumption is a desired property. This thesis addresses the problem of designing low-power embedded internet systems (EIS) used in COTS-based sensor networks. A design methodology based on reactivity and analysability is presented. It is shown that a methodical choice of hardware components is not enough: thorough considerations regarding the software are also required. The purely reactive high-level language Timber is suggested as a suitable software model for implementing reactive and analysable systems. Timber’s strong type system, non-blocking execution model and implicit mutual exclusion, together with its capability to execute without an underlying operating system, endorse implementation of correct and robust systems. The deadline-based notion of Timber provides natural means to describe a system’s real-time behaviour. A method for automatic, accurate and safe static worst-case execution time (WCET) analysis of Timber is also presented. This is an important step towards schedulability analysis and low-power scheduling. Ultimately, reactive hardware together with a Timber-based software design methodology will relieve the system designer from the task of manual low-power optimisation.
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| 8. |
- Östmark, Åke, et al.
(författare)
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Mobile medical applications made feasible through use of EIS platforms
- 2003
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Ingår i: Proceedings of the 20th IEEE Instrumentation and Measurement Technology Conference. - : IEEE Communications Society. - 0780377052 ; , s. 292-295
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Konferensbidrag (refereegranskat)abstract
- Monitoring of medical parameters often limits the mobility of the patient, eg., to the hospital. We present the first steps toward a solution where the patient is offered safety, while allowed the mobility to carry on with daily activities. A pulse oximeter is interfaced to a wireless sensor platform. The sensor system acts as a Bluetooth device providing a TCP/IP interface for configuration and maintenance. This allows user interaction through standardized WWW-browser technology. The sensor provides platform independent client software for data presentation. Sensor data can be transferred over IP/UDP and displayed in real time on the client device.
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