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- Karlsson, Anette, et al.
(författare)
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Automatic and Quantitative Assessment of Total and Regional Muscle Tissue Volume using Multi-Atlas Segmentation
- 2014
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Accurate and precise assessment of human muscle tissue is important for further understanding of different muscle diseases and syndromes. We present a rapid whole body MR method for automatic quantification of total and regional muscle volume. The method is based on multi-atlas segmentation of intensity corrected water-fat separated images. The method was validated with a leave-one-out approach, using manually segmented atlases from 10 subjects as ground truth. The result gave a coefficient of variation on total muscle volume equal to 1.25±1.35 % (mean ± standard deviation). The method enables cost-efficient large-scale studies, investigating conditions such as sarcopenia and muscular dystrophies.
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