| 1. |
- Aad, G., et al.
(författare)
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- 2012
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Aad, G., et al.
(författare)
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- 2012
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swepub:Mat__t (refereegranskat)
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| 3. |
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| 4. |
- Aad, G., et al.
(författare)
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- 2012
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Tidskriftsartikel (refereegranskat)
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| 5. |
- Öztaş, Ahmet M., et al.
(författare)
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Re-evaluation of Ωk of the normalised Friedmann-Lemaître-Robertson-Walker model : Implications for Hubble constant determinations
- 2021
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Ingår i: New Astronomy. - : Elsevier. - 1384-1076 .- 1384-1092. ; 88
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Tidskriftsartikel (refereegranskat)abstract
- The description of spacetime is an fundamental problem of cosmology. We explain why the current assignments of spacetime geometries for Ωk of the Friedmann-Lemaître-Robertson-Walker (FLRW) model are probably incorrect and suggest more useful descriptions. We show that Ωk represents not only curvature but the influence of matter density on the extent of spacetime between massive objects. Recent analyses of supernovae type Ia (SNe Ia) and HII/GEHR data with the FLRW model present the best fits with a small value for Ωm and a large Ωk. These results are consistent with our Universe exhibiting sparse matter density and quasi-Euclidean geometry and the small Ωm value agrees with Big Bang nucleosynthesis calculations. We suggest the geometry of our current Universe is better described by a value for Ωk≈1 rather than 0. As an example we extend the FLRW model towards the Big Bang and discover a simple explanation of how matter creation developed into the currently geometrically flat Universe with sparse, homogeneous, isotropic matter and energy distributions. Assigning Ωk≈1 to describe quasi-Euclidean spacetime geometry is also useful for estimating H0 and should help resolve the “tension” surrounding current estimates by different investigators.
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| 6. |
- Özkaya Sahin, Gülsen, et al.
(författare)
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Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.
- 2010
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Ingår i: PLoS Pathogens. - : Public Library of Science (PLoS). - 1553-7366 .- 1553-7374. ; 6:9
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Tidskriftsartikel (refereegranskat)abstract
- Neutralizing antibodies (NAb) able to react to heterologous viruses are generated during natural HIV-1 infection in some individuals. Further knowledge is required in order to understand the factors contributing to induction of cross-reactive NAb responses. Here a well-established model of experimental pathogenic infection in cynomolgus macaques, which reproduces long-lasting HIV-1 infection, was used to study the NAb response as well as the viral evolution of the highly neutralization-resistant SIVmac239. Twelve animals were infected intravenously with SIVmac239. Antiretroviral therapy (ART) was initiated ten days post-inoculation and administered daily for four months. Viral load, CD4(+) T-cell counts, total IgG levels, and breadth as well as strength of NAb in plasma were compared simultaneously over 14 months. In addition, envs from plasma samples were sequenced at three time points in all animals in order to assess viral evolution. We report here that seven of the 12 animals controlled viremia to below 10(4) copies/ml of plasma after discontinuation of ART and that this control was associated with a low level of evolutionary divergence. Macaques that controlled viral load developed broader NAb responses early on. Furthermore, escape mutations, such as V67M and R751G, were identified in virus sequenced from all animals with uncontrolled viremia. Bayesian estimation of ancestral population genetic diversity (PGD) showed an increase in this value in non-controlling or transient-controlling animals during the first 5.5 months of infection, in contrast to virus-controlling animals. Similarly, non- or transient controllers displayed more positively-selected amino-acid substitutions. An early increase in PGD, resulting in the generation of positively-selected amino-acid substitutions, greater divergence and relative high viral load after ART withdrawal, may have contributed to the generation of potent NAb in several animals after SIVmac239 infection. However, early broad NAb responses correlated with relatively preserved CD4(+) T-cell numbers, low viral load and limited viral divergence.
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| 7. |
- Berndtsson, Inger, 1957, et al.
(författare)
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- 2007
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Ingår i: Nya Synvärlden. - 1401-4742. ; :1, s. 17-19
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Denna artikel handlar om hur vi som professionella inom rehabilitering/habilitering för personer med synnedsättning/blindhet kan arbeta för att tillsammans dela och utveckla ny kunskap inom våra respektive områden.
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| 8. |
- Anderson, Helén, 1954-, et al.
(författare)
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- 2009
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Konferensbidrag (refereegranskat)
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| 9. |
- Aad, G., et al.
(författare)
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- 2011
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Tidskriftsartikel (refereegranskat)
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| 10. |
- Aad, G., et al.
(författare)
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- 2012
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Tidskriftsartikel (refereegranskat)
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