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Sökning: WFRF:(Tham J.) > (2010-2014)

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  • Strömdahl, H, et al. (författare)
  • Prevalence of faecal ESBL carriage in the community and in a hospital setting in a county of Southern Sweden.
  • 2011
  • Ingår i: European Journal of Clinical Microbiology and Infectious Diseases. - : Springer Science and Business Media LLC. - 1435-4373 .- 0934-9723. ; 30, s. 1159-1162
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to investigate the prevalence of extended-spectrum beta-lactamase (ESBL)-producing bacteria in patients at various hospital wards and in a group of relatively healthy volunteers, in order to obtain greater knowledge on how common these bacterial strains are in hospital settings and in the general community. Participants (n = 427) were enrolled at a University Hospital and at Primary Health Care Units (PHCUs) in Sweden in 2008 and 2010. The participants provided rectal swabs, which were tested for the occurrence of ESBL-producing bacteria. Positive samples were analysed with polymerase chain reaction (PCR) methods for bacterial strain typing and ESBL phylogroups. In 2008, the prevalence was 2.1% (2/96) in PHCU subjects and 1.8% (2/113) in hospital patients. In 2010, the prevalence was 3.0% (3/100) in PHCU subjects and 6.8% (8/118) in hospital patients. The dominating phylogroups were CTX-M-1 and CTX-M-9. All ESBL-positive isolates were Escherichia coli. We found a higher prevalence of ESBL faecal carriage than expected, both in the hospital setting and in the PHCU group.
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  • Tham, J. C., et al. (författare)
  • The role of bariatric surgery in the treatment of diabetes
  • 2014
  • Ingår i: Therapeutic Advances in Chronic Disease. - : SAGE Publications Ltd. - 2040-6223 .- 2040-6231. ; 5:3, s. 149-157
  • Tidskriftsartikel (refereegranskat)abstract
    • The obesity epidemic contributes to approximately 44% of the world's type 2 diabetes burden. Bariatric surgery is an effective treatment for type 2 diabetes mellitus in patients with morbid obesity as it improves glycaemia, blood pressure, lipids and inflammation. This review describes the evidence supporting the addition of bariatric surgery to the treatment algorithms used by diabetologists. We emphasize the need to view bariatric surgery as an adjuvant therapy which should not be used instead of but rather together with best medical therapy. © The Author(s), 2014.
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