| 1. |
- Lloyd-Spets, Anita, et al.
(författare)
-
SiC based field effect gas sensors for industrial applications
- 2001
-
Ingår i: Physica status solidi. A, Applied research. - 0031-8965 .- 1521-396X. ; 185:1, s. 15-25
-
Tidskriftsartikel (refereegranskat)abstract
- The development and field-testing of high-temperature sensors based on silicon carbide devices have shown promising results in several application areas. Silicon carbide based field-effect sensors can be operated over a large temperature range, 100-600 degreesC, and since silicon carbide is a chemically very inert material these sensors can be used in environments like exhaust gases and flue gases from boilers. The sensors respond to reducing gases like hydrogen, hydrocarbons and carbon monoxide. The use of different temperatures, different catalytic metals and different structures of the gate metal gives selectivity to different gases and arrays of sensors can be used to identify and monitor several components in gas mixtures. MOSFET sensors based on SIC combine the advantage of simple circuitry with a thicker insulator, which increases the long term stability of the devices. In this paper we describe silicon carbide MOSFET sensors and their performance and give: examples of industrial applications such as monitoring of car exhausts and flue gases. Chemometric methods have been used for the evaluation of the data.
|
|
| 2. |
|
|
| 3. |
- Sjöblom, Tobias, et al.
(författare)
-
Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis.
- 2001
-
Ingår i: Cancer Res. - 0008-5472. ; 61:15, s. 5778-83
-
Tidskriftsartikel (refereegranskat)abstract
- Dermatofibrosarcoma protuberans (DFSP) and giant cell fibroblastoma (GCF) are recurrent, infiltrative skin tumors that presently are treated with surgery. DFSP and GCF tumors are genetically characterized by chromosomal rearrangements fusing the collagen type Ialpha1 (COLIA1) gene to the platelet-derived growth factor B-chain (PDGFB) gene. It has been shown that the resulting COL1A1/PDGF-B fusion protein is processed to mature PDGF-BB. Autocrine PDGF receptor stimulation has therefore been predicted to contribute to DFSP and GCF tumor development and growth. Here we demonstrate presence of activated PDGF receptors in primary cultures derived from six different DFSP and GCF tumors. Three of the primary cultures were further characterized; their in vitro growth displayed an increased sensitivity to treatment with the PDGF receptor tyrosine kinase inhibitor STI571, as compared with normal fibroblasts. Transplantable tumors, displaying a DFSP-like histology, were established from one of the DFSP primary cultures. Treatment of tumor-bearing severe combined immunodeficient mice with STI571 reduced tumor growth. The growth-inhibitory effects in vitro and in vivo occurred predominantly through induction of tumor cell apoptosis. Our study demonstrates growth-inhibitory effects of PDGF receptor antagonists on human DFSP- and GCF-derived tumor cells and demonstrates that autocrine PDGF receptor stimulation provides antiapoptotic signals contributing to the growth of these cells. These findings suggest targeting of PDGF receptors as a novel treatment strategy for DFSP and GCF.
|
|
| 4. |
- Svenningstorp, H., et al.
(författare)
-
Detection of HC in exhaust gases by an array of MISiC sensors
- 2001
-
Ingår i: Sensors and actuators. B, Chemical. - 0925-4005 .- 1873-3077. ; 77:1-2, s. 177-185
-
Tidskriftsartikel (refereegranskat)abstract
- Future legislations for car emissions make direct measurements in exhaust gases of hydrocarbon (HC) as well as CO and NOx interesting. Robust sensors that can stand the high temperature and rough environment in the exhaust gases are needed. Silicon carbide has the advantage of being a chemically very inert material, which, due to its high band gap, is a semiconductor even at temperatures around 800°C. Catalytic metal insulator silicon carbide Schottky diode sensors respond to gases like H2, HC, NOx in exhaust gases. The choice of catalytic metal, structure of the metal, and the operation temperature determines the response pattern to different gases. Here we will demonstrate that an array of different MISiC sensors to some extent predicts the HC concentration in gasoline exhaust gases. Chemometric methods are used for the evaluation of the signals. © 2001 Elsevier Science B.V.
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
- Lloyd-Spets, Anita, et al.
(författare)
-
High temperature catalytic metal field effect transistor for industrial applications
- 2000
-
Ingår i: Sensors and actuators. B, Chemical. - 0925-4005 .- 1873-3077. ; 70:1-3, s. 67-76
-
Tidskriftsartikel (refereegranskat)abstract
- Field effect chemical sensors, utilising silicon carbide as semiconductor, can be operated at high temperature and in rough environments. Gas sensitive field effect transistors, MISiCFET, are now developed (ACREO, Kista in Sweden). This will increase the number of possible applications for field effect gas sensors. The first batch of MISiCFET devices is possible to operate in intermittent pulses of hydrogen/oxygen up to 775°C. At temperature above 600°C, the gas response of the MISiC devices has very short time constants for a change between oxidising and reducing atmosphere and cylinder specific monitoring of a combustion engine has been demonstrated. Other industrial applications, like exhaust diagnosis and flue gas monitoring, have been demonstrated by the use of MISiC Schottky diodes at lower temperatures, 200°C-500°C.
|
|
| 10. |
|
|
