SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Turner Stephen) "

Sökning: WFRF:(Turner Stephen)

  • Resultat 1-10 av 124
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Ademuyiwa, Adesoji O., et al. (författare)
  • Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
  • 2016
  • Ingår i: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
  •  
2.
  •  
3.
  •  
4.
  •  
5.
  • Bombarda, F., et al. (författare)
  • Runaway electron beam control
  • 2019
  • Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 1361-6587 .- 0741-3335. ; 61:1
  • Tidskriftsartikel (refereegranskat)
  •  
6.
  •  
7.
  •  
8.
  •  
9.
  •  
10.
  • Feitosa, Mary F., et al. (författare)
  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
  • 2018
  • Ingår i: PLOS ONE. - : Public library science. - 1932-6203. ; 13:6
  • Tidskriftsartikel (refereegranskat)abstract
    • Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcohol consumption interaction for BP might identify additional BP loci and contribute to the understanding of alcohol-related BP regulation. We conducted a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions. In Stage 1, genome-wide discovery meta-analyses in approximate to 131 K individuals across several ancestry groups yielded 3,514 SNVs (245 loci) with suggestive evidence of association (P <1.0 x 10(-5)). In Stage 2, these SNVs were tested for independent external replication in individuals across multiple ancestries. We identified and replicated (at Bonferroni correction threshold) five novel BP loci (380 SNVs in 21 genes) and 49 previously reported BP loci (2,159 SNVs in 109 genes) in European ancestry, and in multi-ancestry meta-analyses (P < 5.0 x 10(-8)). For African ancestry samples, we detected 18 potentially novel BP loci (P< 5.0 x 10(-8)) in Stage 1 that warrant further replication. Additionally, correlated meta-analysis identified eight novel BP loci (11 genes). Several genes in these loci (e.g., PINX1, GATA4, BLK, FTO and GABBR2 have been previously reported to be associated with alcohol consumption. These findings provide insights into the role of alcohol consumption in the genetic architecture of hypertension.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 124
Typ av publikation
tidskriftsartikel (98)
forskningsöversikt (9)
bokkapitel (7)
konferensbidrag (3)
samlingsverk (redaktörskap) (2)
bok (2)
visa fler...
rapport (1)
doktorsavhandling (1)
visa färre...
Typ av innehåll
refereegranskat (115)
övrigt vetenskapligt/konstnärligt (6)
populärvet., debatt m.m. (2)
Författare/redaktör
Goloborod'ko, V (33)
Jones, G. (32)
Bowden, M. (32)
Duran, I (32)
Ambrosino, G (32)
Ariola, M (32)
visa fler...
Ash, A (32)
Avotina, L (32)
Baciero, A (32)
Balboa, I (32)
Balshaw, N (32)
Barnsley, R (32)
Batistoni, P (32)
Boboc, A (32)
Bolzonella, T (32)
Braic, V (32)
Brett, A (32)
Brezinsek, S (32)
Buratti, P (32)
Carman, P (32)
Carvalho, I (32)
Carvalho, P (32)
Chernyshova, M (32)
Ciric, D (32)
Coelho, R (32)
Coffey, I (32)
Collins, S (32)
Coombs, D (32)
Craciunescu, T (32)
Cramp, S (32)
Croci, G (32)
Crombe, K (32)
Cruz, N (32)
Cseh, G (32)
Curuia, M (32)
Delabie, E (32)
Dittmar, T (32)
Fasoli, A (32)
Fischer, U (32)
Flanagan, J (32)
Formisano, A (32)
Frigione, D (32)
Gelfusa, M (32)
Gherendi, M (32)
Giacomelli, L (32)
Giovannozzi, E (32)
Gohil, P (32)
Goodyear, A (32)
Graham, B (32)
Groth, M (32)
visa färre...
Lärosäte
Uppsala universitet (74)
Kungliga Tekniska Högskolan (42)
Chalmers tekniska högskola (32)
Karolinska Institutet (30)
Lunds universitet (22)
Umeå universitet (15)
visa fler...
Stockholms universitet (9)
Göteborgs universitet (6)
Linköpings universitet (6)
Sveriges Lantbruksuniversitet (4)
Örebro universitet (2)
Linnéuniversitetet (1)
Karlstads universitet (1)
Högskolan Dalarna (1)
Naturhistoriska riksmuseet (1)
visa färre...
Språk
Engelska (123)
Italienska (1)
Forskningsämne (UKÄ/SCB)
Naturvetenskap (59)
Medicin och hälsovetenskap (40)
Teknik (17)
Samhällsvetenskap (5)
Humaniora (3)
Lantbruksvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy