| 1. |
- Andersson, Lena, et al.
(författare)
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Hydrolysis of galactolipids by human pancreatic lipolytic enzymes and duodenal contents
- 1995
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Ingår i: Journal of Lipid Research. - 1539-7262. ; 36:6, s. 1392-1400
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Tidskriftsartikel (refereegranskat)abstract
- Monogalactosyldiacylglycerols (MGDG), digalactosyldiacylglycerols (DGDG) and sulfoquinovosyldiacylglycerols (SQDG) are major lipids in vegetable food. Their digestion and absorption are unknown. This study examines the hydrolysis of galactolipids in vitro with human duodenal contents, pancreatic juice, and purified human pancreatic lipases. Galactolipids were incubated with human duodenal contents, pancreatic juice, pure pancreatic carboxyl ester lipase (CEL), and colipase-dependent lipase with colipase (Lip-Col). Hydrolysis was estimated as release of free fatty acids and by the use of [3H]galactose or [3H]fatty acid-labeled DGDG. Pancreatic juice and duodenal contents hydrolyzed DGDG to fatty acids, digalactosylmonoacylglycerol (DGMG) and water-soluble galactose-containing compounds. The hydrolysis of DGDG was bile salt-dependent and had a pH optimum at 6.5-7.5. Human pancreatic juice released fatty acids from MGDG, DGDG, and SQDG. Purified CEL hydrolyzed all three substrates; the hydrolysis rate was MGDG > SQDG > DGDG. Pure Lip-Col had activity toward MGDG but had little activity against DGDG. Separation of pancreatic juice by Sephadex G100 gel filtration chromatography revealed two peaks with galactolipase activity that coincided with CEL (molecular mass 100 kD) and lipase (molecular mass 50 kD) peaks. In contrast to pure Lip-Col enzymes of the latter peak were as active against DGDG as against MGDG. Thus, DGDG is hydrolyzed both by CEL and by a pancreatic enzyme(s) with a molecular mass of 40-50 kD to fatty acids and lyso DGDG. MGDG, DGDG, and SQDG are all hydrolyzed by human pancreatic juice. Pure CEL hydrolyzed all three substrates.
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| 2. |
- Forssell, Urban, et al.
(författare)
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Efficiency of Prediction Error and Instrumental Variable Methods for Closed-loop Identification
- 1998
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Ingår i: Proceedings of the 37th IEEE Conference on Decision and Control. - Linköping : Linköping University Electronic Press. - 0780343948 ; , s. 1287-1288 vol.2
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- We study the efficiency of a number of closed-loop identification methods. Results will be given for methods based on the prediction error approach as well as those based on the instrumental variable approach. Moreover, interesting insights in the properties of a recently suggested subspace method for closed-loop identification are obtained by exploring the links between this method and the instrumental variable method.
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| 3. |
- Gestblom, B, et al.
(författare)
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Dielectric characterization of substituted diols
- 1997
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Ingår i: LIQUID CRYSTALS. - : TAYLOR & FRANCIS LTD. - 0267-8292. ; 22:4, s. 459-462
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Dielectric properties of four diols having different chemical structures of the hydrophobic part were determined by the time domain spectroscopy method in the frequency range from c. 15 MHz to c. 7 GHz. The static permittivity clearly reflects the changes
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| 4. |
- Henriksen, Egil, et al.
(författare)
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An echocardiographic study comparing male Swedish elite orienteers with other elite endurance athletes
- 1997
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Ingår i: American Journal of Cardiology. - 0002-9149 .- 1879-1913. ; 79:4, s. 521-524
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Tidskriftsartikel (refereegranskat)abstract
- Between 1979 and 1992, there were 16 known cases of sudden unexpected cardiac death among young Swedish orienteers, whose autopsies showed myocarditis to be a common finding. Therefore, 96 elite orienteers and 47 controls underwent echocardiography, showing left ventricular wall motion abnormalities in 9% of the orienteers compared with 4% in the controls.
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| 5. |
- JONGMAN, JR, et al.
(författare)
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HIGH-SPIN STATES IN EU-148
- 1995
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Ingår i: NUCLEAR PHYSICS A. - : ELSEVIER SCIENCE BV. ; 581:1, s. 165-188
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- High-spin states in the odd-odd nucleus Eu-148, populated by a carbon-13 induced reaction on a lanthanum target, were investigated with several different tools of in-beam nuclear spectroscopy. The low-energy levels show collective excitations, interpreted
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| 6. |
- Rosdahl, Hans, et al.
(författare)
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Influence of adrenergic agonists on the release of amino acids from rat skeletal muscle studied by microdialysis.
- 1998
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Ingår i: Acta Physiologica Scandinavica. - 0001-6772 .- 1365-201X. ; 163:4, s. 349-60
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Tidskriftsartikel (refereegranskat)abstract
- The microdialysis technique was used to study the effects of adrenergic agonists on the release of amino acids from rat skeletal muscle. The release was monitored indirectly by measurements of interstitial concentrations. To distinguish metabolic from vasoactive effects, the adrenaline and isoprenaline results were compared with those of vasopressin, alpha-agonists and adenosine. As determined by the microdialysis ethanol technique, adrenaline, alpha-agonists and vasopressin induced vasoconstriction, whereas isoprenaline and adenosine induced vasodilatation. The lactate-to-pyruvate ratio increased fourfold with adrenaline (P < 0.001) and by 54% with isoprenaline (P < 0.05), whereas no change was observed with alpha-agonists and adenosine. Vasopressin induced a fivefold increase in the lactate-to-pyruvate ratio (P < 0.001), but with an unchanged pyruvate concentration, indicating that the effect may have been secondary to ischaemia. Adrenaline induced a twofold and vasopressin a 34% increase in the concentration of alanine (P < 0.001), whereas isoprenaline, adenosine and alpha-agonists had no significant effect. Adrenaline-perfusion induced an initial anabolic effect as evidenced by a reduced concentration of tyrosine. A significant decrease in the glutamate-to-glutamine ratio was observed with adrenaline and isoprenaline (22 and 27%, P < 0.01) whereas alpha-agonists, vasopressin and adenosine were without effect. In conclusion, the present study showed that adrenaline, via a beta-adrenergically mediated activation of glycogenolysis, possibly further stimulated by ischaemia, induced an increased release of alanine from skeletal muscle. The study indicates a beta-adrenergic stimulation on the glutamine synthetase step and a short lasting anabolic effect of adrenaline. Differences in the magnitude of the effects of adrenaline and isoprenaline could be related to their different vasoactive properties.
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| 7. |
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