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Träfflista för sökning "WFRF:(Vázquez García Ignacio) srt2:(2015-2019)"

Search: WFRF:(Vázquez García Ignacio) > (2015-2019)

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1.
  • Hudson, Lawrence N, et al. (author)
  • The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
  • 2017
  • In: Ecology and Evolution. - : John Wiley & Sons. - 2045-7758. ; 7:1, s. 145-188
  • Journal article (peer-reviewed)abstract
    • The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity.
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2.
  • Li, Jing, et al. (author)
  • Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales
  • 2019
  • In: Molecular Biology and Evolution. - : Oxford University Press (OUP). - 1537-1719 .- 0737-4038. ; 36:4, s. 691-708
  • Journal article (peer-reviewed)abstract
    • Pre-existing and de novo genetic variants can both drive adaptation to environmental changes, but their relative contributions and interplay remain poorly understood. Here we investigated the evolutionary dynamics in drug-treated yeast populations with different levels of pre-existing variation by experimental evolution coupled with time-resolved sequencing and phenotyping. We found a doubling of pre-existing variation alone boosts the adaptation by 64.1% and 51.5% in hydroxyurea and rapamycin, respectively. The causative pre-existing and de novo variants were selected on shared targets: RNR4 in hydroxyurea and TOR1, TOR2 in rapamycin. Interestingly, the pre-existing and de novo TOR variants map to different functional domains and act via distinct mechanisms. The pre-existing TOR variants from two domesticated strains exhibited opposite rapamycin resistance effects, reflecting lineage-specific functional divergence. This study provides a dynamic view on how pre-existing and de novo variants interactively drive adaptation and deepens our understanding of clonally evolving populations.
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journal article (2)
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peer-reviewed (2)
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Hylander, Kristoffer (1)
Granjon, Laurent (1)
Abrahamczyk, Stefan (1)
Jonsell, Mats (1)
Brunet, Jörg (1)
Kolb, Annette (1)
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Sáfián, Szabolcs (1)
Li, Jing (1)
Persson, Anna S. (1)
Franzén, Markus (1)
Jung, Martin (1)
Nilsson, Sven G (1)
Warringer, Jonas, 19 ... (1)
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Entling, Martin H. (1)
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Herzog, Felix (1)
Knop, Eva (1)
Tscharntke, Teja (1)
Aizen, Marcelo A. (1)
Petanidou, Theodora (1)
Stout, Jane C. (1)
Woodcock, Ben A. (1)
Poveda, Katja (1)
Mustonen, Ville (1)
Alignier, Audrey (1)
Batáry, Péter (1)
Krauss, Jochen (1)
Steffan-Dewenter, In ... (1)
Westphal, Catrin (1)
Wolters, Volkmar (1)
Edenius, Lars (1)
Rader, Romina (1)
Medina, Nagore G. (1)
Baeten, Lander (1)
Dynesius, Mats (1)
de Sassi, Claudio (1)
Luskin, Matthew S. (1)
Slade, Eleanor M. (1)
Mikusinski, Grzegorz (1)
Gilbert, Benjamin (1)
Felton, Annika (1)
Samnegård, Ulrika (1)
Barlow, Jos (1)
Ficetola, Gentile F. (1)
Yu, Douglas W. (1)
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