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Signal regulatory p...
Signal regulatory protein alpha is present in several neutrophil granule populations and is rapidly mobilized to the cell surface to negatively fine-tune neutrophil accumulation in inflammation
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- Stenberg, Åsa (author)
- Umeå universitet,Histologi med cellbiologi
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- Karlsson, Anna, 1967 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research
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- Feuk-Lagerstedt, Elisabeth, 1949 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research
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- Christenson, Karin (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research
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- Bylund, Johan, 1975 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research
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- Oldenborg, Anna (author)
- Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Mo. , USA
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- Vesterlund, Liselotte (author)
- Karolinska Institutet,Umeå universitet,Histologi med cellbiologi,Department of Biosciences and Nutrition at Novum, Karolinska Institute, Stockholm , Sweden
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- Matozaki, Takashi (author)
- Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe , Japan
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- Sehlin, Janove (author)
- Umeå universitet,Histologi med cellbiologi
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- Oldenborg, Per-Arne (author)
- Umeå universitet,Histologi med cellbiologi
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(creator_code:org_t)
- 2014-02-07
- 2014
- English.
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In: Journal of Innate Immunity. - : S. Karger AG. - 1662-811X .- 1662-8128. ; 6:4, s. 553-560
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Abstract
Subject headings
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- Signal regulatory protein alpha (SIRPα) is a cell surface glycoprotein with inhibitory functions, which may regulate neutrophil transmigration. SIRPα is mobilized to the neutrophil surface from specific granules, gelatinase granules, and secretory vesicles following inflammatory activation in vitro and in vivo. The lack of SIRPα signaling and the ability to upregulate SIRPα to the cell surface promote neutrophil accumulation during inflammation in vivo.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Andra medicinska och farmaceutiska grundvetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Other Basic Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Keyword
- Neutrophils
- Inflammation
- Signal regulatory protein alpha
- Chemotactic factor
- Skin window
- Exudate
- Neutrophils; Inflammation; Signal regulatory protein alpha; Chemotactic factor; Skin window; Exudate
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Stenberg, Åsa
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Karlsson, Anna, ...
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Feuk-Lagerstedt, ...
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Christenson, Kar ...
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Bylund, Johan, 1 ...
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Oldenborg, Anna
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Vesterlund, Lise ...
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Matozaki, Takash ...
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Sehlin, Janove
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Oldenborg, Per-A ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Other Basic Medi ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Immunology in th ...
- Articles in the publication
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Journal of Innat ...
- By the university
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Umeå University
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University of Gothenburg
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Karolinska Institutet