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Träfflista för sökning "WFRF:(Vogl C.) srt2:(2010-2014)"

Sökning: WFRF:(Vogl C.) > (2010-2014)

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1.
  • Sharma, Manish, et al. (författare)
  • Older Patients with Myeloma Derive Similar Benefit from Autologous Transplantation
  • 2014
  • Ingår i: Biology of blood and marrow transplantation. - : Elsevier BV. - 1083-8791 .- 1523-6536. ; 20:11, s. 1796-1803
  • Tidskriftsartikel (refereegranskat)abstract
    • Autologous hematopoietic cell transplantation (AHCT) for plasma cell myeloma is performed less often in people >70 years old than in people <= 70 years old. We analyzed 11,430 AHCT recipients for plasma cell myeloma prospectively reported to the Center for International Blood and Marrow Transplant Research between 2008 and 2011, representing the majority of US AHCT activity during this period. Survival (OS) was compared in 3 cohorts: ages 18 to 59 years (n = 5818), 60 to 69 years (n = 4666), and >70 years (n = 946). Median OS was not reached for any cohort. In multivariate analysis, increasing age was associated with mortality (P = .0006). Myeloma-specific mortality was similar among cohorts at 12%, indicating an age-related effect on nonmyeloma mortality. Analyses were performed in a representative subgroup comparing relapse rate, progression-free survival (PFS), and nonrelapse mortality (NRM). One-year NRM was 0% for age >70 years and 2% for other ages (P = not significant). The three-year relapse rate was 56% in age 18 to 59 years, 61% in age 60 to 69 years, and 63% age >70 (P = not significant). Three-year PFS was similar at 42% in age 18 to 59 years, 38% in age 60 to 69 years, and 33% in age >70 years (P = not significant). Postrelapse survival was significantly worse for the older cohort (P = .03). Older subjects selected for AHCT derived similar antimyeloma benefit without worse NRM, relapse rate, or PFS.
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3.
  • Milestad, Rebecka, et al. (författare)
  • Building farm resilience through farmers´ experimentation
  • 2010
  • Ingår i: Proceedings of the 9th European IFSA Symposium. ; , s. 770-778
  • Konferensbidrag (refereegranskat)abstract
    • This paper discusses how farmers’ experimentation can be a building block for resilience at theirfarms. A core challenge in natural resource management is to enhance resource users’ learning and capabilitiesso that they can make informed decisions and adaptively manage the land. In other words, resource users, suchas farmers, need to develop their capacity to manage for resilience of agro‐ecosystems so that the ecosystemservices from agriculture (like food, fibres, cultural values, etc) can be sustained and enhanced. One way todevelop this capacity may be through experimentation on the farm. Experimentation is one way for farmers tolearn about and manage their environment. Farmers’ experiments can be described as the activity ofintroducing something totally or partially new at the farm and to evaluate the feasibility of this introduction.We use literature about farmers’ experiments and resilience theory to build the arguments of this paper. Theoutcome of experiments can be management changes, new insights, or technology. These can be passed on toothers in the farmers’ social network and potentially be built into institutional memory at higher scales. Wecontend that farmers’ experiments have a strong relation to learning and resilience building in farming systems.
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