| 1. |
- Ahlberg, Simon, et al.
(författare)
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The IFD03 information fusion demonstrator
- 2004
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Ingår i: Proceedings of the Seventh International Conference on Information Fusion, FUSION 2004. - 917056115X ; , s. 936-943
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Konferensbidrag (refereegranskat)abstract
- The paper discusses a recently developed demonstrator system where new ideas in tactical information fusion may be tested and demonstrated. The main services of the demonstrator are discussed, and essential experience from the use and development of the system is shared.
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| 2. |
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| 3. |
- Berglund, Johan, et al.
(författare)
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5-y follow-up study of patients with neuroborreliosis
- 2002
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Ingår i: Scandinavian Journal of Infectious Diseases. - : Taylor & Francis. - 0036-5548 .- 1651-1980. ; 34:6, s. 421-425
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this follow-up study was to determine the long-term outcome of strictly classified cases of neuroborreliosis treated with antibiotics. A one-year prospective population-based survey of Lyme borreliosis was conducted in southern Sweden, between 1992 and 1993. A total of 349 identified cases with suspected neuroborreliosis were followed up 5 years later. Medical records were reviewed and all participants filled in a questionnaire. Of those classified with definite neuroborreliosis 114/130 completed the follow-up, of whom 111 had completed the initial antibiotic treatment. Of the 114 patients followed up, 86 (75%) had recovered completely and 70 (61%) had recovered within 6 months. Residual neurological symptoms such as facial palsy, concentration disorder, paresthesia and/or neuropathy were reported by 28/114. No significant differences between different antibiotic treatments were observed in terms of occurrence of sequelae. To conclude, we found that 25% (95% confidence interval 17-33%) of the patients suffered from residual neurological symptoms 5 years post-treatment. However, the clinical outcome of treated neuroborreliosis is favourable as only 14/114 (12%) of the patients had sequelae that influenced their daily activity post-treatment. Early diagnosis and treatment would seem to be of great importance in order to avoid such sequelae.
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| 4. |
- Berglund, Johan, et al.
(författare)
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A 5-years follow-up of patients with neuroborreliosis.
- 2002
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Konferensbidrag (refereegranskat)abstract
- The objective of this follow-up study was to determine the long-term outcome in patients treated with antibiotics for strictly classified cases of neuroborreliosis. A one-year prospective population-based survey of Lyme borreliosis was conducted in southern Sweden, 1992-1993. Totally 349 identified cases with suspected neuroborreliosis were registered. Of those, 130 were classified as definitively neuroborreliosis and followed up five years later. Medical records were reviewed and all participants filled in a questionnaire. Totally, 114/130 (88%) completed the follow-up of whom 111/114 (97%) had fulfilled the initial antibiotic treatment. Of these, 86/114 (75%) had recovered completely and 70 (61%) recovered within six months. However 28/114 (25%) suffered from remaining neurological symptoms such as facial palsy, concentration disorder, paresthesia and/or neuropathy. The longer the duration from the neurological symptoms onset to antibiotic treatment the higher was the rate of sequelae. Of those who were treated within 30 days 5/32 (16%) and of those who were treated after 30 days 16/41 (39%) respectively, reported sequelae. Women suffered significantly more from sequelae compared to men, this difference was not seen among the children. No significant differences between the different antibiotic treatments given and experience of sequelae were seen. To conclude, we found that 25% (95% CI 17% to 33%) of the patients suffered from remaining neurological symptoms five years post treatment. However, the clinical outcome of treated neuroborreliosis is favourable as only 14/114 (12%) of the patients had sequelae that influenced their daily activity post treatment and early diagnosis and treatment seems to be of great importance to possibly avoid also these cases.
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| 5. |
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Control of Complex Systems
- 2001
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- The world of artificial systems is reaching hitherto undreamed-of levels of complexity. Surface traffic, electricity distribution, mobile communications, etc., demonstrate that problems are arising that are beyond classical scientific or engineering knowledge. In order that our ability to control such systems should not be hindered by lack of comprehension, there is an on-going effort to understand them. This book is an example of the types of approach that European researchers are using to tackle problems derived from systems' complexity. It has grown out of activities in the Control of Complex Systems (COSY) research program the goals of which are to promote multi-disciplinary activity leading to a deeper understanding and further development of control technologies for complex systems and if possible, to develop the theory underlying such systems. The material in this book represents a selection of the results of the COSY program and is organised as a collection of essays of varying nature: surveys of essential areas, discussion of specific problems, case studies, and benchmark problems. Topics covered include: Modelling complex physical systems; Passivity-based control of non-linear systems; Aspects of fault identification and fault tolerance; Control design; Learning control; Satellite attitude control. Complex systems appear in many different fields and for this reason this book should be of interest to scientists, researchers and industrial engineers with a broad spectrum of experience.
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| 6. |
- Meyer, Peter R, et al.
(författare)
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Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation
- 2003
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Ingår i: Journal of Virology. - 0022-538X .- 1098-5514. ; 77:6, s. 3871-3877
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Tidskriftsartikel (refereegranskat)abstract
- Finger insertion mutations of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) (T69S mutations followed by various dipeptide insertions) have a multinucleoside resistance phenotype that can be explained by decreased sensitivity to deoxynucleoside triphosphate (dNTP) inhibition of the nucleotide-dependent unblocking activity of RT. We show that RTs with SG or AG (but not SS) insertions have three- to fourfold-increased unblocking activity and that all three finger insertion mutations have threefold-decreased sensitivity to dNTP inhibition. The additional presence of M41L and T215Y mutations increased unblocking activity for all three insertions, greatly reduced the sensitivity to dNTP inhibition, and resulted in defects in in vitro DNA chain elongation. The DNA chain elongation defects were partially repaired by additional mutations at positions 210, 211, and 214. These results suggest that structural communication between the regions of RT defined by these mutations plays a role in the multinucleoside resistance phenotype.
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