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Träfflista för sökning "WFRF:(Wang Shun Chung) "

Search: WFRF:(Wang Shun Chung)

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1.
  • 2019
  • Journal article (peer-reviewed)
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2.
  • Lee, Bumhyun, et al. (author)
  • The Impact of the Group Environment on the Molecular Gas and Star Formation Activity
  • 2021
  • In: Proceedings of the International Astronomical Union. - 1743-9213 .- 1743-9221. ; , s. 136-139
  • Book chapter (other academic/artistic)abstract
    • At least half of the local galaxies reside in galaxy groups, which indicates that the group is the common environment where galaxies evolve. Therefore, it is important to probe how significantly galaxies are affected by group environmental processes, in order to obtain a better understanding of galaxy evolution. We carried out a new CO imaging survey for 31 galaxies in the IC 1459 and NGC 4636 groups, using the Atacama Compact Array, to study the effect of the group environment on the molecular gas properties and the star formation activity. With our resolved CO data, combined with high-resolution H i images, we find asymmetric CO and H i distributions in the group galaxies. Compared to isolated galaxies, group members have relatively low molecular gas fraction and low star formation rate. These results suggest that the group environment can change the properties of cold gas components and star formation in group galaxies.
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3.
  • Hoch, Nicolas C, et al. (author)
  • Molecular basis of the essential s phase function of the rad53 checkpoint kinase
  • 2013
  • In: Molecular and Cellular Biology. - 0270-7306 .- 1098-5549. ; 33:16, s. 3202-3213
  • Journal article (peer-reviewed)abstract
    • The essential yeast kinases Mec1 and Rad53, or human ATR and Chk1, are crucial for checkpoint responses to exogenous genotoxic agents, but why they are also required for DNA replication in unperturbed cells remains poorly understood. Here we report that even in the absence of DNA-damaging agents, the rad53-4AQ mutant, lacking the N-terminal Mec1 phosphorylation site cluster, is synthetic lethal with a deletion of the RAD9 DNA damage checkpoint adaptor. This phenotype is caused by an inability of rad53-4AQ to activate the downstream kinase Dun1, which then leads to reduced basal deoxynucleoside triphosphate (dNTP) levels, spontaneous replication fork stalling, and constitutive activation of and dependence on S phase DNA damage checkpoints. Surprisingly, the kinase-deficient rad53-K227A mutant does not share these phenotypes but is rendered inviable by additional phosphosite mutations that prevent its binding to Dun1. The results demonstrate that ultralow Rad53 catalytic activity is sufficient for normal replication of undamaged chromosomes as long as it is targeted toward activation of the effector kinase Dun1. Our findings indicate that the essential S phase function of Rad53 is comprised by the combination of its role in regulating basal dNTP levels and its compensatory kinase function if dNTP levels are perturbed.
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  • Result 1-3 of 3
Type of publication
journal article (2)
book chapter (1)
Type of content
peer-reviewed (2)
other academic/artistic (1)
Author/Editor
Kelly, Daniel (1)
Bengtsson-Palme, Joh ... (1)
Nilsson, Henrik (1)
Kelly, Ryan (1)
Li, Ying (1)
Moore, Matthew D. (1)
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Liu, Fang (1)
Zhang, Yao (1)
Jin, Yi (1)
Raza, Ali (1)
Rafiq, Muhammad (1)
Zhang, Kai (1)
Khatlani, T (1)
Kahan, Thomas (1)
Sörelius, Karl, 1981 ... (1)
Batra, Jyotsna (1)
Roobol, Monique J (1)
Backman, Lars (1)
Yan, Hong (1)
Schmidt, Axel (1)
Lorkowski, Stefan (1)
Thrift, Amanda G. (1)
Zhang, Wei (1)
Hammerschmidt, Sven (1)
Patil, Chandrashekha ... (1)
Wang, Jun (1)
Pollesello, Piero (1)
Conesa, Ana (1)
El-Esawi, Mohamed A. (1)
Zhang, Weijia (1)
Li, Jian (1)
Marinello, Francesco (1)
Frilander, Mikko J. (1)
Wei, Pan (1)
Badie, Christophe (1)
Zhao, Jing (1)
Li, You (1)
Ho, Luis C. (1)
Bansal, Abhisheka (1)
Rahman, Proton (1)
Parchi, Piero (1)
Verdes-Montenegro, L ... (1)
Polz, Martin (1)
Ijzerman, Adriaan P. (1)
Subhash, Santhilal, ... (1)
Quinn, Terence J. (1)
Uversky, Vladimir N. (1)
Gemmill, Alison (1)
Zhang, Yi (1)
Meule, Adrian (1)
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University
Chalmers University of Technology (2)
University of Gothenburg (1)
Umeå University (1)
Uppsala University (1)
Halmstad University (1)
Stockholm University (1)
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Lund University (1)
Karolinska Institutet (1)
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Language
English (3)
Research subject (UKÄ/SCB)
Natural sciences (2)
Medical and Health Sciences (2)

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