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Sökning: WFRF:(Warusavitarne J) > (2020) > Temporary faecal di...

Temporary faecal diversion in ileocolic resection for Crohns disease: is there an impact on long-term surgical recurrence?

Bolckmans, R. (författare)
Oxford Univ Hosp NHS Fdn Trust, England
Singh, S. (författare)
Oxford Univ Hosp NHS Fdn Trust, England
Ratnatunga, K. (författare)
Oxford Univ Hosp NHS Fdn Trust, England
visa fler...
Wickramasinghe, D. (författare)
St Marks Hosp, England
Sahnan, K. (författare)
St Marks Hosp, England
Adegbola, S. (författare)
St Marks Hosp, England
Kalman, Thordis Disa, 1959- (författare)
Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US
Jones, H. (författare)
Oxford Univ Hosp NHS Fdn Trust, England
Travis, S. (författare)
Oxford Univ Hosp NHS Fdn Trust, England
Warusavitarne, J. (författare)
St Marks Hosp, England
Myrelid, Pär, 1970- (författare)
Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US
George, B. (författare)
Oxford Univ Hosp NHS Fdn Trust, England
visa färre...
 (creator_code:org_t)
2019-12-10
2020
Engelska.
Ingår i: Colorectal Disease. - : WILEY. - 1462-8910 .- 1463-1318. ; 22:4, s. 430-438
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Aim Temporary faecal diversion after ileocolic resection (ICR) for Crohns disease reduces postoperative anastomotic complications in high-risk patients. The aim of this study was to assess if this approach also reduces long-term surgical recurrence. Method This was a multicentre retrospective review of prospectively maintained databases. Patient demographics, medical and surgical details were collected by three specialist centres. All patients had undergone an ICR between 2000 and 2012. The primary end-point was surgical recurrence. Results Three hundred and twelve patients (80%) underwent an ICR without covering ileostomy (one stage). Seventy-seven (20%) had undergone an ICR with end ileostomy/double-barrel ileostomy/enterocolostomy followed by closure (two stage). The median follow-up was 105 months [interquartile range (IQR) 76-136 months]. The median time to ileostomy closure was 9 months (IQR 5-12 months). There was no significant difference in surgical recurrence between the one- and two-stage groups (18% vs 16%, P = 0.94). We noted that smokers (20% vs 34%, P = 0.01) and patients with penetrating disease (28% vs 52%, P amp;lt; 0.01) were more likely to be defunctioned. A reduced recurrence rate was observed in the small high-risk group of patients who were smokers with penetrating disease behaviour treated with a two-stage strategy (0/10 vs 4/7, P = 0.12). Conclusion Despite having higher baseline risk factors, the results in terms of rate of surgical recurrence over 9 years are similar for patients having a two-stage compared with a one-stage procedure.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

Nyckelord

Ileocolic resection; Crohns disease; recurrence; ileostomy

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

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