| 1. |
- Calén, H., et al.
(författare)
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Detector setup for a storage ring with an internal target
- 1996
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 379:1, s. 57-75
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Tidskriftsartikel (refereegranskat)abstract
- A detector setup for the cooler storage ring CELSIUS is described. The setup detects particles produced in interactions between the internal beam and a cluster-jet target. Particles emitted in the forward direction are measured by means of arrays of plastic scintillators and proportional counters. Particles, particularly photons, emitted more isotropically are measured by means of two calorimeters containing CsI(Na) crystals. The performance of the setup is given for neutral meson production in proton-proton and proton-deuteron interactions in the energy range 290-1360 MeV.
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| 2. |
- Carlsson, Maria L., 1959, et al.
(författare)
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The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice
- 1999
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Ingår i: J Neural Transm. - 0300-9564. ; 106:2, s. 123-9
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of the present study was to compare the effectiveness of the selective 5-HT2A antagonist M100907 in different psychosis models. The classical neuroleptic haloperidol was used as reference compound. Two hyperdopaminergia and two hypoglutamatergia mouse models were used. Hyperdopaminergia was produced by the DA releaser d-amphetamine or the DA uptake inhibitor GBR 12909. Hypoglutamatergia was produced by the un-competitive NMDA receptor antagonist MK-801 or the competitive NMDA receptor antagonist D-CPPene. M100907 was found to counteract the locomotor stimulant effects of the NMDA receptor antagonists MK-801 and D-CPPene, but spontaneous locomotion, d-amphetamine- and GBR-12909-induced hyperactivity were not significantly affected. Haloperidol, on the other hand, antagonized both NMDA antagonist- and DA agonist-induced hyperactivity, as well as spontaneous locomotion in the highest dose used. Based on the present and previous results we draw the conclusion that 5-HT2A receptor antagonists are particularly effective against behavioural anomalies resulting from hypoglutamatergia of various origins. The clinical implications of our results and conclusions would be that a 5-HT2A receptor antagonist, due to i a the low side effect liability, could be the preferable treatment strategy in various disorders associated with hypoglutamatergia; such conditions might include schizophrenia, childhood autism and dementia disorders.
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| 3. |
- Bondar, A., et al.
(författare)
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The pp → ppπ0 reaction near the kinematical threshold
- 1995
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Ingår i: Physics Letters B. - : Elsevier. - 0370-2693 .- 1873-2445. ; 356:1, s. 8-12
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Tidskriftsartikel (refereegranskat)abstract
- The reaction pp → ppπ0 has been measured using electron-cooled protons incident on an internal gas-jet target at seven different incident beam energies, from 280.7 MeV (1 MeV above the reaction threshold) up to 310.2 MeV. The pions were measured by their decay photons. In the overlapping energy region, the measured total cross sections agree with those measured in a recent Indiana experiment. The angular distributions are consistent with a 3P0 → 1S0S0 transition in the full energy range studied. The kinematical distributions are well described when taking into account the final state and the Coulomb interactions.
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| 4. |
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| 5. |
- Calén, H., et al.
(författare)
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The pp → ppη reaction near the kinematical threshold
- 1996
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Ingår i: Physics Letters B. - : Elsevier. - 0370-2693 .- 1873-2445. ; 366:1-4, s. 39-43
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Tidskriftsartikel (refereegranskat)abstract
- The pp → ppη reaction has been measured at six energies close to threshold, from 1258 MeV to 1352 MeV, using an internal cluster gas jet target in the CELSIUS storage ring. The η is detected through its decay photons, in an array of CsI detectors, and the forward-going protons are detected in a plastic scintillator spectrometer. A complete event reconstruction is obtained at the higher energies in the measured interval. The new data, together with earlier data, give an accurate determination of the energy dependence close to threshold. The influence of the η-proton FSI is seen in the total cross section data as well as in a Dalitz plot of the η-p invariant mass distributions.
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