| 1. |
- Wennberg, Anna Lena, 1968, et al.
(författare)
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Attitudes towards new assisted reproductive technologies in Sweden: a survey in women 30-39 years of age.
- 2016
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Ingår i: Acta obstetricia et gynecologica Scandinavica. - : Wiley. - 1600-0412 .- 0001-6349. ; 95:1, s. 38-44
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Tidskriftsartikel (refereegranskat)abstract
- Novel pathways to parenthood (oocyte cryopreservation, allowance of surrogacy, uterus transplantation and assisted reproductive treatments (ART) for single women) are currently being discussed. This study investigates women's attitudes towards oocyte cryopreservation and ART- procedures which are not allowed or are still investigational in Sweden and whether the attitudes differ between urban women and women from a national cohort.
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| 2. |
- Wennberg, Anna Lena, 1968, et al.
(författare)
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Effect of maternal age on maternal and neonatal outcomes after assisted reproductive technology
- 2016
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Ingår i: Fertility and Sterility. - : Elsevier BV. - 0015-0282. ; 106:5, s. 1142-1149
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To compare the effect of maternal age on assisted reproductive technology (ART) and spontaneous conception (SC) pregnancies regarding maternal and neonatal complications. Design: Nordic retrospective population-based cohort study. Data from national ART registries were cross-linked with national medical birth registries. Patient(s): A total of 300,085 singleton deliveries: 39,919 after ART and 260,166 after SC. Main Outcome Measure(s): Hypertensive disorders in pregnancy (HDP), placenta previa, cesarean delivery, preterm birth (PTB; <37 weeks), low birth weight (LBW; <2,500 g), small for gestational age (SGA), and perinatal mortality (>= 28 weeks). Adjusted odds ratios (AORs) were calculated. Associations between maternal age and outcomes were analyzed. Result(s): The risk of placenta previa (AOR 4.11-6.05), cesarean delivery (AOR 1.18-1.50), PTB (AOR 1.23-2.19), and LBW (AOR 1.44-2.35) was significantly higher in ART than in SC pregnancies for most maternal ages. In both ART and SC pregnancies, the risk of HDP, placenta previa, cesarean delivery, PTB, LBW, and SGA changed significantly with age. The AORs for adverse neonatal outcomes at advanced maternal age (>35 years) showed a greater increase in SC than in ART. The change in risk with age did not differ between ART and SC for maternal outcomes at advanced maternal age. Conclusion(s): Having singleton conceptions after ART results in higher maternal and neonatal outcome risks overall, but the impact of age seems to be more pronounced in couples conceiving spontaneously. (C) 2016 by American Society for Reproductive Medicine.
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| 3. |
- Wennberg, Anna Lena, 1968, et al.
(författare)
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Elective oocyte freezing for nonmedical reasons: a 6-year report on utilization and in vitro fertilization results from a Swedish center
- 2019
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Ingår i: Acta Obstetricia Et Gynecologica Scandinavica. - : Wiley. - 0001-6349 .- 1600-0412. ; 98:11, s. 1429-1434
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: Elective oocyte freezing started in Sweden in 2011, a few years after oocyte vitrification was introduced internationally as an effective method for cryopreservation of oocytes. The objective of this study is to describe the age of the women who choose to undergo this procedure, the subsequent utilization of cryopreserved oocytes and the results of autologous in vitro fertilization (IVF). Material and methods: We conducted a descriptive follow-up study of a subset of women at a private IVF center. All women (n=254) who electively vitrified oocytes at Nordic IVF Göteborg between 1 August 2011 and 31 August 2017 were included. Ages at oocyte vitrification and warming, number of vitrified oocytes and results of IVF are presented. Results: A total of 254 women underwent elective oocyte freezing and 38 (15%) of these returned to use their cryopreserved oocytes for autologous IVF before November 2018. In the total cohort, the mean number of vitrified oocytes per woman, undergoing one or more oocyte retrievals, was 7.6 (range 1-37). Their mean age at first vitrification was 36.9years (range 23-43years). The mean ages for the subset of women that subsequently used their oocytes for IVF were 38.7 and 42.7years at vitrification and oocyte warming, respectively. Forty-nine oocyte warming cycles resulting in 42 fresh and 16 frozen embryo transfers, have been performed. Cumulative live birth rate/ongoing pregnancy rates are 63%, 26% and 0% in women of ages 36-37, 38-39 and ≥40years of age at vitrification, respectively. Five babies have been born and there are 5 ongoing pregnancies. Conclusions: Elective oocyte freezing has been offered in Sweden for >7years. The utilization rate has so far been low. Pregnancy results after oocyte warming and IVF are encouraging when oocytes are cryopreserved at an age below 40years. © 2019 Nordic Federation of Societies of Obstetrics and Gynecology
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