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Sökning: WFRF:(Wetzel K.) > (2020-2023) > Do Weightbearing Re...

Do Weightbearing Restrictions Cause Excess Weight Gain in Children With LEGG-Calve-Perthes Disease?

Novotny, Susan A. (författare)
Gillette Childrens Specialty Healthcare, St Paul, MN USA.;Univ Minnesota, Dept Rehabil Med, Minneapolis, MN USA
Hailer, Yasmin, 1972- (författare)
Uppsala universitet,Ortopedi
Laine, Jennifer C. (författare)
Gillette Childrens Specialty Healthcare, St Paul, MN USA.;Univ Minnesota, Dept Orthopaed Surg, Minneapolis, MN USA
visa fler...
Wetzel, Martha (författare)
Emory Univ, Rollins Sch Publ Hlth, Dept Hlth Policy & Management, Atlanta, GA USA
Gillespie, Scott E. (författare)
Emory Sch Med, Dept Pediat, Pediat Biostat Core, Atlanta, GA USA
Gilbert, Shawn R. (författare)
Univ Alabama Birmingham, Dept Orthopaed Surg, Birmingham, AL USA
Goldstein, Rachel Y. (författare)
Childrens Hosp Angeles, Childrens Orthoped Ctr, Los Angeles, CA USA
Kim, Harry K. W. (författare)
Scottish Rite Children, Ctr Excellence Hip, Dallas, TX USA.;Univ Texas Southwestern Med Ctr Dallas, Dept Orthopaed Surg, Dallas, TX USA
Schrader, Tim (författare)
Childrens Healthcare Atlanta, Atlanta, GA USA
visa färre...
Gillette Childrens Specialty Healthcare, St Paul, MN USA;Univ Minnesota, Dept Rehabil Med, Minneapolis, MN USA Ortopedi (creator_code:org_t)
Lippincott Williams & Wilkins, 2023
2023
Engelska.
Ingår i: Journal of Pediatric Orthopaedics. - : Lippincott Williams & Wilkins. - 0271-6798 .- 1539-2570. ; 43:1, s. 31-36
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background: Restricted weight bearing is commonly prescribed in Legg-Calve-Perthes Disease (LCPD), raising concerns of causing overweight or obesity. This study utilizes prospectively collected data to address the following questions: (1) does body mass index (BMI) Z-score increase over the course of LCPD follow-up; (2) is having a BMI category of normal, overweight, or obese at baseline associated with BMI Z-score changes over the course of follow-up; and (3) is the duration of weight bearing restrictions (no restrictions, <3, 3 to <6, 6 to 9, or >9 mo) associated with BMI Z-score changes.Methods: Data of 130 children aged 5 to 12 years with unilateral early-stage LCPD were extracted from an international database. Nation-specific BMI Z-scores and percentile-based weight categories were determined, and the duration of follow-up and weight bearing restrictions were calculated. Longitudinal changes in BMI Z-scores were evaluated for the 3 study questions using mixed effects linear regression models with surgery as a covariate. Sensitivity analyses were used to determine the influence of socio-cultural background (USA vs. India) for each study question.Results: During the 35.5 +/- 15.9 months of follow-up, no statistically significant increase in BMI Z-scores was observed across the entire cohort, or following stratification by baseline weight categories or the duration of the weight bearing restriction. Sensitivity analyses indicated that patients in the USA had no change in their BMI Z-score. When stratified by weight categories, the normal weight of US children had a small increase in their BMI Z-score (0.005 per mo, 95% confidence interval: 0.0002, 0.009), but this was not seen in other BMI categories. The cohort of Indian children had a small but significant decrease in their BMI Z-score (-0.005/mo, 95% CI: -0.009, -0.0002). After stratification by weight categories, a small decrease of the BMI Z-score was observed only in the Indian overweight children (-0.016 per mo, 95% CI: -0.027, -0.005) and no other BMI category.Conclusions: Weightbearing restrictions over the course of follow-up for our cohort of children with early-stage LCPD were not associated with clinically meaningful increases of BMI Z-scores. Weight gain is multi-factorial and probably not caused by weight bearing restrictions alone.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Ortopedi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Orthopaedics (hsv//eng)

Nyckelord

LEGG-Calve-Perthes Disease (LCPD)
BMI
longitudinal
weight bearing restrictions
Pediatrik
Pediatrics

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ref (ämneskategori)
art (ämneskategori)

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