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Träfflista för sökning "WFRF:(Wolf A.) srt2:(1995-1999)"

Sökning: WFRF:(Wolf A.) > (1995-1999)

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  • Hoffknecht, A, et al. (författare)
  • Recombination of F6+ with free electrons at very low energies
  • 1999
  • Ingår i: Physica Scripta. Topical Issues. ; T80B, s. 298-300
  • Tidskriftsartikel (refereegranskat)abstract
    • Radiative and dielectronic recombination of F6+ have been studied at the heavy ion storage ring TSR in Heidelberg. For a detailed investigation of rate enhancement effects at very low electron-ion center-of-mass energies experimental parameters such as the magnetic guiding field, the electron density and the adiabatic expansion factor of the electron beam have been varied systematically. Whereas measurements at different electron densities show no influence on the enhancement and while a variation of the expansion factor evokes the predicted behaviour, we see an increase of the enhancement with increasing axial magnetic field between 20 mT and 70 mT.
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  • Smith, C.A., et al. (författare)
  • A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid
  • 1997
  • Ingår i: Journal of Medical Genetics. - : BMJ. - 0022-2593 .- 1468-6244. ; 34:9, s. 758-60
  • Tidskriftsartikel (refereegranskat)abstract
    • Human arylamine N-acetyltransferase (NAT) activity is determined by two distinct genes, NAT1 and NAT2, and the classical acetylation polymorphism in NAT2 has been associated with a variety of disorders, including lupus erythematosus and arylamine induced cancers. Over 50% of the white population exhibit a slow acetylator phenotype. The genetic basis of the defect has been identified and several DNA based assays are available for genotyping studies. We present here a simplified, rapid PCR based assay for the identification of the major slow acetylator genotypes and validate it using isoniazid as probe drug. This assay was 100% predictive of phenotype. The three genotypes (homozygous mutated, heterozygous, and homozygous rapid) corresponded to a trimodal distribution of Ac-INH/INH metabolic ratios (slow, intermediate, and rapid) without overlapping.
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  • Resultat 1-10 av 13

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