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- Koene, B, et al.
(författare)
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Institutional entrepreneurship: comparing Dutch and Swedish temporary work agencies
- 2007
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Ingår i: the EHBA conference in Geneva, 13-15 September 2007.
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Konferensbidrag (refereegranskat)abstract
- Most studies of institutional entrepreneurship emphasize the influence of institutional entrepreneurs on processes of institutional change. Relatively little attention is paid to the interaction between the institutional entrepreneur and the institutional environment. Our aim is to fill this void by a comparative study of the institutional development of the Dutch and Swedish temporary work agency industries from the 1960s until the present, emphasizing the periods after their formal legalization in 1965 and 1991 respectively. The comparison shows the important influence of the different national contexts on the dynamics of institutionalization, the evolving industry identity and accountability. Our paper thus shows how the process of synchronizing of (international) industry experience with the (national) societal experience with the industry’s product is not a simple process of knowledge transfer and reflects the important interaction between institutional entrepreneurs and their environment.
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- Luijsterburg, MS, et al.
(författare)
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Heterochromatin protein 1 is recruited to various types of DNA damage
- 2009
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Ingår i: The Journal of cell biology. - : Rockefeller University Press. - 1540-8140 .- 0021-9525. ; 185:4, s. 577-586
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Tidskriftsartikel (refereegranskat)abstract
- Heterochromatin protein 1 (HP1) family members are chromatin-associated proteins involved in transcription, replication, and chromatin organization. We show that HP1 isoforms HP1-α, HP1-β, and HP1-γ are recruited to ultraviolet (UV)-induced DNA damage and double-strand breaks (DSBs) in human cells. This response to DNA damage requires the chromo shadow domain of HP1 and is independent of H3K9 trimethylation and proteins that detect UV damage and DSBs. Loss of HP1 results in high sensitivity to UV light and ionizing radiation in the nematode Caenorhabditis elegans, indicating that HP1 proteins are essential components of DNA damage response (DDR) systems. Analysis of single and double HP1 mutants in nematodes suggests that HP1 homologues have both unique and overlapping functions in the DDR. Our results show that HP1 proteins are important for DNA repair and may function to reorganize chromatin in response to damage.
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- Nilsson, Pernilla, 1969-, et al.
(författare)
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How will we understand what we teach? : Primary student teachers´ perceptions of how to develop subject matter knowledge and a positive attitude towards physics
- 2009
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Konferensbidrag (refereegranskat)abstract
- It is well known that many primary teachers have a negative attitude towards science as well as limited science subject matter knowledge. During a course, 40 primary science student teachers were video recorded to follow their activities during practical experiments in physics. After every workshop, they watched the video in order to reflect on their activities and communication in the group. After the course a questionnaire including a storyline was used to elicit the student teachers´ perceptions of their development of subject matter knowledge during the course. Finally, five participants were interviewed. The results give an insight into factors that primary student teachers described as important to develop subject matter knowledge and a more positive attitude towards physics.
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